Case 2 Flashcards
Which of the following hematologic diseases is Pica most likely seen?
a. G6PD deficiency
b. Thalassemia
c. Megaloblastic anemia
d. Iron deficiency anemia
D
All of the following statements about acute myelocytic leukemia are true EXCEPT.
a. It is more common in adults.
b. It has worse prognosis than chronic myeloid leukemia.
c. The bone marrow examination is essential.
d. The presence of Philadelphia positive chromosome
D
Target of immune mediated mechanism in dengue fatal disease involves which of the following.
a. Spleen
b. Liver
c. Kidney
d. Bone marrow
B
All of the following are common findings in acute lymphocytic leukemia EXCEPT.
a. Epistaxis
b. Fever
c. Gum hypertrophy
d. None of the options
D
Which of the following hemoglobin levels as criterion pregnant women indicating physiological
anemia based on WHO?
a. <130 g/L
b. <120 g/L
c. <110 g/L (1st trimester)
d. <100 g/L
C
Which of the following primary causes of anemia have occurrence of postural hypotension and
tachycardia usually seen?
a. Acute blood loss
b. Hemolysis
c. Iron deficiency
d. Vitamin B12 deficiency
C
Target cells are seen in which of the following.
a. Thalassemia
b. Iron deficiency anemia
c. Folate deficiency anemia
d. Vit. B12 deficiency anemia
A
All of the following are included in the differential diagnosis for microcytic, hypochromic anemia.
Which one is the exception?
a. Sideroblastic anemia
b. Anemia of chronic disease
c. Thalassemia
d. Pernicious anemia- macrocytic
D
The neoplastic proliferation of which of the following cells in Multiple myeloma is.
a. Lymphocytes
b. Granulocytes
c. Plasma cells
d. Monocytes
C
Which of these non- invasive procedures is most likely employed for determination of the body’s
iron storage?
a. Iron stain of bone marrow aspirate
b. Iron tolerance test
c. Red cell protoporphyrin levels
d. Serum ferritin determination
D
Neurological symptoms are seen often in which of the following.
a. Iron deficiency anemia
b. Vitamin B12 deficiency
c. Folate deficiency
d. Any of the options
D
Which of the following about folic acid deficiency anemia is correct?
a. The folate is synthesized in the human.
b. The ingestion of alcohol interferes with the absorption of folate.
c. The folic acid deficiency anemia results in neurologic manifestations.
d. The supplementation with 1ug daily will replenish folate stores.
B OR C
Which of the following is the type of anemia for Iron Deficiency?
a. Normocytic, normochromic
b. Microcytic, hypochromic
c. Macrocytic
d. Hemolytic
B
All of the following clinical findings may increase the risk of mortality EXCEPT.
a. History of previous dengue
b. Hypotension on admission
c. Narrow pulse pressure on admission
d. None of the options
D
Which of the following cells usually seen in patients with severe anemia in peripheral blood smear?
a. Target cells
b. Poikilocytes
c. Microcytic cells
d. All of the options
B
Which of the following complications is most likely to
occur during oral iron therapy?
a. Erythrocytosis
b. Neurologic symptoms
c. Gastrointestinal discomfort
d. Polycythemia vera
C
What type of ADR is managed with IV Epinephrine or Hydrocortisone during medical emergency?
a. Type I
b. Type II
c. Type III
d. Type IV
A
All of the following are associated with Sickle Cell Anemia. Which one is the EXCEPTION?
a. Bleeding disease
b. Vasoocclusive crisis
c. Aplastic crisis
d. Chest syndrome
A
Which of the following laboratory evaluation is considered the cornerstone for diagnosis of anemia?
a. Bone marrow aspiration with biopsy
b. Complete blood count
c. Hematocrit level determination
d. Red blood corpuscle indices
B
Which of the following laboratory tests is the most useful test to document iron deficiency?
a. Complete blood count
b. Serum ferritin
c. Serum transferrin
d. Serum iron
A
All of the following are pathogenesis of leukocytosis in peripheral blood leukocyte count. Which one is the exception?
a. The size of myeloid and lymphoid precursor and storage cell pools in the bone marrow, thymus circulation and peripheral tissues.
b. The size of myeloid and lymphoid precursor and storage cell pools in the bone marrow, thymus and circulation.
c. The rate of release of cells from the storage pools into the circulation.
d. The proportion of cells that are adherent to blood vessel walls at any time.
A
Which of the following statements about the serum iron level is correct?
a. The serum iron level is an indirect measure of circulating transferrin.
b. The serum iron level is a measure of transferrin saturation.
c. The serum iron level is a measure of free
d. The serum iron level is the amount of circulating iron bound to transferrin.
D
Which of the following is the rich source of cryoprecipitate?
a. Factor X
b. Factor VII
c. Factor VIII
d. Thromboplastin
C
Which part of the GI tract is the site of iron absorption?
a. Stomach
b. Duodenum
c. Jejunum
d. Ileum
B
Heinz bodies are seen often in which of the following hematologic diseases.
a. G6PD deficiency
b. Hereditary spherocytosis
c. Sickle cell anemia
d. Hereditary elliptocytosis
A
Which of the following is the most common form of leukemia in children?
a. Acute lymphoblastic leukemia
b. Chronic lymphocytic leukemia
c. Acute myeloid leukemia
d. Chronic myeloid leukemia
A
Which of the following statements about pernicious anemia is correct?
a. The corticosteroid therapy may reverse the pathologic findings in pernicious anemia.
b. The complete vitamin B12 deficiency develops abruptly after total achiorhydria and with loss of intrinsic factor
c. . The pathologic specimens from gastric mucosa shows infiltrating antibody- producing T-cells.
d. The initial event in the pathogenetic cascade leading to pernicious anemia Begins in the ileum where vitamin B12 is.
D
The primary site of folate absorption is mostly located in which of the following
a. Proximal jejunum
b. Duodenum
c. Ileum
d. Cecum
A
According to CPG on dengue in children, the presence of the following symptom/s should be admitted.
a. Abdominal pain
b. Vomiting
c. Saddleback pattern of fever
d. Any of the options
D
Which of the following types of anemia is most likely associated with leukemia?
a. Normocytic, normochromic
b. Microcytic, hypochromic
c. Normocytic, hypochromic
d. Microcytic, normochromic
A
Grey baby syndrome occurs in which of the following drugs?
a. Doxycycline
b. Penicillin
c. Clarithromycin
d. Chloramphenicol
D
Which of the following is/ are the usual CBC values for G6PD deficiency anemia EXCEPT?
a. Low MCV and MCHC > microcytic, hypochromic
b. High RDW
c. Normal WBC and platelet
d. None of the options
A
Which of these laboratory values is most likely diagnostic for iron deficiency anemia?
a. Abnormal peripheral blood smear
b. Low Mean corpuscle volume
c. Increased reticulocyte count
d. Low serum ferritin level
D
A 6-year old girl accidentally tripped and fell on the ground. This caused some minor cuts on her palms and arms. Which of the following is the primary hemostatic reaction of her body to the injury?
a. Clot formation
b. Complement activation of the alternative pathway
c. Platelet adhesion
d. Platelet plug
e. Vasoconstriction
E
Gum infiltration is usually seen in which of the following types of leukemia?
a. Acute erythroleukemia
b. Acute monocytic leukemia
c. Acute myelomonocytic leukemia
d. Acute promyelocytic leukemia
B
Which of the following drugs inhibits the topoisomerase II that leads to DNA breakage?
a. Daunorubicin
b. Cisplatin
c. Bleomycin
d. Cytarabine
A
All of the following are myeloproliferative neoplasms. Which one is the exception?
a. Acute myelogenous leukemia
b. Polycythemia vera
c. Primary myelofibrosis
d. Essential thrombocytopenia
D
Which of the following best describes the proposed mechanism of action of antimalarials?
a. It bind TNF-alpha
b. It inhibits B cell proliferation
c. It inhibits lymphotoxin-alpha
d. It suppresses T-lymphocyte response
D