Case 16-20 Flashcards
SAAG >1.1 indicated for portal hypertension seen in
Cardiac ascites, cirrhosis, Budd-Chiari syndrome
SAAG <1.1 g/dl (absence of portal hypertension) SEEN IN
TB, peritoneal carcinomatosis, pancreatic ascites, nephrotic syndrome
This patient v,ith chronic alcohol misuse and epigastric pain that vvorsens postprandially, suggestive of …..
chronic pancreatitis
Chronic pancreatitis most commonly occurs in patients with ……
chronic alcohol use disorders
Pancreatic ascites is a rare complication of …….
chronic pancreatitis
Pancreatic ascites is typically
serosanguinous or straw-colored with analysis showing
high amylase (often >1000 U/L), high total protein (> 2.5 g/dl ), and low serum-ascites albumin gradient (SAAG) (<1.1, indicating the absence of portal hypertension).
is straw yellow with normal amylase, low total protein, and high SAAG.
Ascites from cirrhosis
Budd-Chiari syndrome (ie, hepatic venous obstruction) can cause ascites but it is usually straw yellow with
normal amylase, high total protein, and high SAAG.
Patients typically have severe right upper quadrant pain with jaundice, hepatic encephalopathy, and possibly variceal bleeding.
present with malignant ascites, which is typically bloody (not serosanguinous) with normal amylase, high total protein, and low SAAG.
Hepatocellular carcinoma
Pancreatic ascites results from
damage to the pancreatic duct with leakage of pancreatic juice into the peritoneal space.
Paracentesis findings of pancreatic ascites include
serosanguinous or yellow fluid with high amylase, high total protein, and low serum-ascites albumin gradient
constant epigastric pain and weight loss require further evaluation with
CT scan of the abdomen
is used in the initial evaluation of patients with painless jaundice, anorexia, or weight loss.
Abdominal ultrasound
Approximately 25° /o of pancreatic cancer is heralded by a recent (<2 years) diagnosis of ……
diabetes mellitus
Risk factors of Acalculous cholecystitis
Severe trauma or recent surgery
• Prolonged fasting or TPN
• Critical illness (eg, sepsis, ICU)
Clinical presentation
Fever, leukocytosis, ⬆️LFTs, RUQ pain , Jaundice & RUQ mass less common
Diagnosis of a calculus cholecystitis
. Abdominal ultrasound (preferred)
•HIDA or CT scan if needed
is most often seen in hospitalized patients who are critically ill
Acalculous cholecystitis
Cause of males ant biliary obstruction
Cholangiocarcinoma
Pancreatidhepatocellular carcinoma
• Metastasis (eg, colon, gastric)
Manifestations of males ant biliary obstruction
. Jaundice, pruritus, acholic stools, dark urine
• Weight loss
. RUQ pain
• RUQ mass or hepatomegaly
• i Direct bilirubin, ALP, GGT
highly lethal malignancy of the bile duct epithelium.
Cholangiocarcinoma
Is transaminases elevated in Cholangiocarcinoma ¿
Normal / mildly elevated
CEA , CA19-9 are ………… in Cholangiocarcinoma but ……. In HCC
Elevated , normal
Risk of Cholangiocarcinoma is great in
Fibropolycystic liver disease or
Primary sclerosing cholangitis
95% with Ulcerative colitis
In Choledocholithiasis CEA and CA-19 are……. , and cachexia is ……..
not typically elevated , unusual