Case 15 Crohn's complications Flashcards
What are the symptoms of Crohn’s disease
fatigue
blood and mucus in stool
abdominal pain
diarrhoea
unintended weight loss
What are the Causes of Crohn’s disease
genetics
smoking
environment - diseases of the west, children grow up germ free environment
immune system- TNF alpha, attack healthy bacteria
infection
What questions would you ask in a history for Crohn’s disease
diet
recent travel
family hx
medications
What blood tests would you need for diagnosis of Crohn’s
inflammation- CRP, ESR
Anaemia- FBC
Infection- WCC count
What stool sample tests are needed for diagnosis of Crohn’s
Parasite
faecal calprotectin
Infections
Blood and mucus
what imaging tests are used in the diagnosis of Crohn’s disease
MRI, CT
Barium swallow- small bowel enema
Colonoscopy- biopsy
What tests are done in the examination in the diagnosis of Crohn’s disease
Pulse
BP
Height
Weight
Temp
Abdomen examination
What is initial treatment of Crohn’s disease
Corticosteroids
- prednisolone
- hydrocortisone injections
what is the additional treatment in Crohn’s disease
immunosuppressants
- azathioprine- safe for pregnancy
- methotrexate- not safe for pregnancy
- mercaptopurine
what is the treatment for severe Crohn’s disease
Biological Therapies
- Infliximab (IV drip)
- Adalimumab (injection)
- both are against TNF alpha
What are the two surgical options for Crohn’s disease
Resection- remove inflamed section
Ileostomy- Divert digestive waste away from inflamed colon
What are less common symptoms of Crohn’s
High temp
nausea
Mouth ulcers
Areas of red swollen skin
vomiting
joint pain and swelling
Where is the site of pain for
- Appendicitis
- small Bowel obstruction
-pancreatitis
- cholecystitis
umbilical, then RLQ
umbilical
LUQ, radiate to back
RUQ
Where is the character of pain for
- Appendicitis
- small Bowel obstruction
-pancreatitis
- cholecystitis
consistent with intermittent cramps
colicky and severe
constant and severe
constant and severe
what are the associated symptoms for
- Appendicitis
- small Bowel obstruction
Anorexia
nausea and vomiting
unable to pass flatus or stool
Rovsing sign for appendicitis
distension/bloating for SB obstruction
what are the associated symptoms for
-pancreatitis
- cholecystitis
Nausea and vomiting
Anorexia and dyspnoea for pancreatitis
Murphys sign for cholecystitis
What are the Exacerbating factors for
- Appendicitis
- small Bowel obstruction
-pancreatitis
- cholecystitis
Movement and coughing
oral intake
movement
fatty foods
What is Rovsing’s Sign
Appendicitis
Press hand on LLQ, pain in RLQ
due to inflamed peritoneum
What are the symptoms of bowel obstruction
Bloating
unable to pass flatus or stool
Colicky abdominal pain
nausea and vomiting
anorexia