Cartilage Tissue Engineering Flashcards
1
Q
What are the 3 types of cartilage?
A
- Hyaline
- Elastic
- Fibrocartilage
2
Q
What are the resident cells within cartilage ?
A
Chondrocytes
3
Q
What is perichondrium ?
A
- dense film of irregular connective that coats cartilage
4
Q
Describe Hyaline/Articular Cartilage
A
- colourless, transparent or ‘glassy’
- often found in joints as it protects bone-on-bone friction
- when present on ‘articulating’ surface of bone joints its refered to as ‘articular cartilage’
- articular chondrocytes produce type II collagen mainly
5
Q
Where can you find chondrocytes ?
A
- spaces in the cartilage matrix claled lacunae
6
Q
What gives the hyaline cartilage matrix its slippery properties?
A
- the abundance of glycosaminoglycans
7
Q
Describe Elastic Cartilage
A
- contains some collagen & an abundance of elastic fibres
- tissue has ability to withstand repeated deformation & return to its original shape
- resident cells = chondrocytes
- found in tissues which forms lobe of ear & epiglottis
8
Q
Describe Fibrocartilage
A
- toughest type of cartilage
- useful at resisting compressive force
- found in intervetebral disk
- contains densely packed collagen fibres which may include type I
- intermediate between dense connective tissue & cartilage & can be difficult to distinguish
- chondrocytes may be spotted in distinct rows
9
Q
What is a Chondron?
A
- a chondrocyte & its associated pericellular matrix
