Cartilage layers Flashcards

1
Q

Lubricin, tangential orientation, progenitor/stem cells, highest collagen concentration, opposes shear

A

Superficial (gliding) zone

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2
Q

Type VI collagen, oblique orientation, opposes compression

A

Transitional (middle) zone

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3
Q

Highest proteoglycans, lowest water, high Aggrecan, low collagen, vertical orientation

A

Deep (radial) zone

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4
Q

Type X collagen, hypertrophic chondrocytes (low activity)

A

Calcified zone

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5
Q

Increase with aging

A

Keratan sulfate, chrondrocyte size, modulus of elasticity

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6
Q

Decrease with aging

A

Water, proteoglycans, number of chondrocytes, chondroitin

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7
Q

Increase with OA

A

Water, chondroitin

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8
Q

Decrease with OA

A

Proteoglycans, keratan sulfate, modulus of elasticity

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9
Q

Collagen types in annulus and in nucleus of disc

A

I and II

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