CartilaGe and reGeneration

Question 1

What are the four basic types of tissue?

Answer 1

Epithelium
Connective Tissue
( Connective Tissue Proper ,Cartilage, Bone, Blood)
Muscle Tissue
Nervous Tissue

Question 2

What are the Functions
of Connective Tissue:

Answer 2

• Provides support, strength, protection, insulation and metabolites.
• Highly vascular and has a good nerve supply (except cartilage and tendons).
• Supplies nutrients, O2 and removes waste from the tissues (blood vessels).
• It has a ground substance with a flexible matrix.
• Fibroblasts produce fibres i.e Collagen, elastic and reticular

Question 3

What is the basic composition of cartilage?

Answer 3

Dense network of collagen fibres.
* Embedded in gelatinous ground substance - consistency of plastic.

Question 4

How does cartilage receive nutrition ?

Answer 4

receive nutrition by diffusion through the gel.

Question 5

where do cells exist in cartilage

Answer 5

Occur at scattered sites through the cartilage

Question 6

where is cartilage found?

Answer 6

Joints, Ribs, Nose, Ear,
Trachea and Intervertebral Discs

Question 7

What are the functions of cartilage

Answer 7

• Structural support,
• Maintain shape
• Absorb shock during physical exercise.

Question 8

what does avascular mean?

Answer 8

having few or no blood vessels

Question 9

why does collagen being avascular matter?

Answer 9

leads to hypoxic environment - limits rate of cell
growth and tissue regeneration.
which then limits the capacity of cartilage to repair itself in the event of damage.

Question 10

what are chondrocytes?

Answer 10

cells responsible for cartilage formation

Question 11

what do lacunae do?

Answer 11

secrete the extracellular matrix (ECM) of cartilage.

Question 12

What is the extra cellular matrix made up of in cartillage

Answer 12

collagens, elastin, glycoproteins and proteoglycans, each of
which is present in varying amounts, depending on the type and
function of cartilage.