Cartilage and bone Flashcards
What does a large ratio of GAGs (glycosaminoglycans) and type II collagen in the ECM permit?
diffusion of substances between blood vessels in surrounding connective tissues and
chondrocytes in the matrix
What does the perichondrium do?
a sheath of dense (irregular) connective tissue that surrounds cartilage
what contains blood vessels serving the cartilage and a small neural component
Perichondrium
What is the most common type of cartilage
Hyaline
What is distinguished by a homogeneous amorphous extra cellular matrix
Hyaline cartilage
Where are chondrocytes found in hyaline cartilage
found within lacunae (spaces within the
ECM)
type II collagen makes up what
bulk of collagen fibers
what type of collage consists in the perichondrium
type i collagen
outer layer of the perichondrium contains what?
fibrous layer – type I collagen and fibroblasts
The inner perichondrium layer has a _____ layer that is filled with what?
chondrogenic layer
– type I collagen and chondroblasts
What is interstitial growth
growth from within the
cartilage proper
How are elastic cartilage distinguished
elastic fibers
what is Fibrocartilage a a combination of?
dense connective tissue and hyaline cartilage
What type oof cartilage is located where resistance to both compression and shearing forces is required of the
tissue:
Fibrocartilage
What are Osteoids
uncalcified and unmineralized