Cartilage and bone Flashcards

1
Q

What does a large ratio of GAGs (glycosaminoglycans) and type II collagen in the ECM permit?

A

diffusion of substances between blood vessels in surrounding connective tissues and
chondrocytes in the matrix

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2
Q

What does the perichondrium do?

A

a sheath of dense (irregular) connective tissue that surrounds cartilage

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3
Q

what contains blood vessels serving the cartilage and a small neural component

A

Perichondrium

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4
Q

What is the most common type of cartilage

A

Hyaline

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5
Q

What is distinguished by a homogeneous amorphous extra cellular matrix

A

Hyaline cartilage

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6
Q

Where are chondrocytes found in hyaline cartilage

A

found within lacunae (spaces within the
ECM)

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7
Q

type II collagen makes up what

A

bulk of collagen fibers

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8
Q

what type of collage consists in the perichondrium

A

type i collagen

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9
Q

outer layer of the perichondrium contains what?

A

fibrous layer – type I collagen and fibroblasts

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10
Q

The inner perichondrium layer has a _____ layer that is filled with what?

A

chondrogenic layer

– type I collagen and chondroblasts

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11
Q

What is interstitial growth

A

growth from within the
cartilage proper

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12
Q

How are elastic cartilage distinguished

A

elastic fibers

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13
Q

what is Fibrocartilage a a combination of?

A

dense connective tissue and hyaline cartilage

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14
Q

What type oof cartilage is located where resistance to both compression and shearing forces is required of the
tissue:

A

Fibrocartilage

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15
Q

What are Osteoids

A

uncalcified and unmineralized

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16
Q

______ are secreted with initial collagen rich materials

A

Osteoid

17
Q

______ represents appositional growth which is completed with subsequent calcification (no
interstitial growth

A

Osteoid

18
Q

Osteoclast rest directly on bone surface where resorption is occurring within enzymatically etched
depressions, or lay within ____

A

cavities called Howship’s lacunae

19
Q

What fibers are bound bone to matrix

A

Sharpley’s fiber

20
Q

What fibers are are bundles of type 1 collagen fibers which penetrate the boone matrix

A

Sharpley’s fibers

21
Q

lamellae arranged in parallel sheets or concentrically around a central canal called what

A

Haversian canal

22
Q

What. do Haversian canals contain

A

blood vessels and nevers, lined by endosteum

23
Q

osteonal (Haversian) canals communicate through transverse ____________ carrying blood vessels and nerves

A

Volkmann canals
(perforating canals)

24
Q

What is a wovern bone

A

immature bone, primary bone

25
Q

what bone is initially formed in skeleton of developing fetus

A

woven bone

26
Q

What type of bone is a non lamellar and has cells randomly arranged

A

Woven bone

27
Q

What are examples of a trabecular bone, spongy bone

A

Cancellous bone (type of lamellar bone)

28
Q

What type of lamellar bone is sponge-like meshwork consisting of trabeculae

A

Cancellous bone

29
Q

What type of bone ossification forms most bone and hyaline cartilage models serves as a precursor

A

Endochondral ossification

30
Q

in diaphysis of fetal long bones- chondrocytes die
after enclosure of cartilage within a collar of woven bone, creating an initial cavity
entered by periosteal osteoblasts and blood vessels

A

Primary ossification centers

31
Q

develop within the epiphysis with cartilage of the
epiphyseal growth plate- separates the epiphyseal and diaphyseal cavities of
bone; responsible for maintaining growth in length (bone lengthening)

A

Secondary ossification centers