Cartilage Flashcards
What are collagen and elastin fibres of connective tissue surrounded by?
Ground substance
What is ground substance made up of? (3)
Proteoglycans
Hyaluronic acid
Water
What is cartilage made up of?
Collagen fibres
Ground substance
Cells
What is the main cartilage type around the joints?
Hyaline cartilage (buffer)
What is hyaline cartilage formed of and what is its layout?
Collagen 2 fibres
Criss-cross layout
What is the principal proteoglycan in cartilage and what does it bind to and what does it form?
Aggrecan
Binds to hyaluronic acid (which are bound to collagen fibres)
Forms a dense package - ideal for high pressure
How does cartilage receive nutrients and what is their type of metabolism?
Chondrocytes - diffusion
Glycolytic metabolism
What is articular cartilage?
Cartilage that lines our joints
What is fibrocartilage?
Fibrocartilage is used for Ligaments, connective tissue and tendons - better for unidirectional forces
What is fibrocartilage made up of?
Collagen 1 and Collagen 2 fibres - aligned int he direction of the forces
What type of cartilage does our invertebrate discs have?
Fibrocartilage
What are tendons and ligaments made of?
Dense connective tissue with unidirectional collagen 1 fibres
What is synovial fluid absorbed and secreted by?
Synovium
What is the synovium made up of?
Cells, capillaries and fibroblasts
How is the buffer effect caused?
Hydration shells of densely packed proteoglycans
