Cartilage Flashcards
The three types of cartilage found in the body are
Hyaline (articular), elastic, fibrocartilage
Nutrient exchange is a function of
Diffusion and movement of interstitial fluid due to loading
(T/F) The most accurate mathematical model to represent cartilage tissue is the quasi-linear viscoelastic model
F - the most accurate is the linear biphasic model; the other two models (quasi-linear viscoelastic and the monophasic viscoelastic models are both more limited)
(T/F) The two major components of hyaline cartilage are proteoglycans and Type I collagen
F - Type II collagen
(T/F) Collagen resists tension in cartilaginous tissues
T
(T/F) Aggrecan fibers are heterogeneously distributed throughout the different layers of cartilage
F - Its pretty evenly distributed
What are the primary modes of loading in articular cartilage
Shear, tension and compression
The time-dependent mechanical behavior during compression is predominantly due to
Fluid movement out of the tissue
Which matrix component is responsible for anchoring cartilage to bone
1) The decreased spacing between the collagen and aggrecan molecules
2) Increase in local charge density as aggrecan molecules (very negative)
The increase in cartilage permeability is due to
Collagen
In what way does fluid flow change between the surface zone and the deep zone
It decreases
In what way does shear strain change between the surface zone to the deep zone
It increases
In what way do compressive strains change from the surface zone to the deep zone
They decrease
