Cartilage Flashcards

1
Q

What is cartilage?

A

Specialized connective tissue providing the skeletal framework of the body.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What does it mean that cartilage is avascular?

A

It has no nerves or lymphatic supply, meaning few or no blood vessels.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the origin of cartilage?

A

Cartilage is derived from embryonic mesenchyme.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the components of the extracellular matrix of cartilage?

A

70-75% water
15-20% collagen
2-10% proteoglycans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Where is hyaline cartilage found?

A

In the trachea.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the functions of hyaline cartilage?

A

Provides a smooth, low-friction surface in joints.
Supports growth and shaping of long bones.
Lines the articular surface of synovial joints.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is unique about chondrocytes in hyaline cartilage?

A

They form isogenous groups surrounded by interterritorial matrix.
They cannot undergo mitosis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What makes elastic cartilage unique?

A

It is more flexible and elastic than other types.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What does the extracellular matrix of elastic cartilage contain?

A

A small amount of amorphous material and a small number of type II collagen.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How does elastic cartilage grow?

A

Appositional growth (from perichondrium).
Interstitial growth.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Does elastic cartilage undergo calcification?

A

No, it does not undergo calcification.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the key features of fibrocartilage?

A

Interlacing strands of fibrous tissue through the matrix.
Provides tensile strength due to collagen.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Where is fibrocartilage found?

A

Symphysis pubis.
Annulus fibrosus of intervertebral discs.
Bone-to-tendon attachments.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Does fibrocartilage have a perichondrium?

A

No, it lacks a distinct perichondrium.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What type of collagen does fibrocartilage contain?

A

Type I and type II collagen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are chondrocytes?

A

Mature cells of cartilage and the only cells present.

17
Q

Can chondrocytes divide?

A

No, they cannot undergo mitosis.

18
Q

Where is type II collagen found?

A

External ear
Intervertebral discs
Spinal cord
Skeletal structures

19
Q

What does type II collagen form?

A

A large area of dense connective tissue with type I collagen.

20
Q

What is chondrogenesis?

A

The process where cartilage is formed from condensed mesenchyme tissue.

21
Q

What is the function of neutrophils?

A

To kill and phagocytose bacteria.

22
Q

What is the structure of neutrophil nuclei?

A

3-5 lobes.

23
Q

What is the function of eosinophils?

A

To kill parasites and modulate local inflammation

24
Q

What is the function of basophils?

A

To release histamine during allergic reactions and modulate inflammation.

25
Q

What are the two types of agranulocytes in cartilage?

A

Lymphocytes: Regulate adaptive immunity.
Monocytes: Precursors of macrophages and other phagocytic cells

26
Q

What is intramembranous ossification?

A

The process that creates a ring with osteocytes.

27
Q

What is endochondral ossification?

A

Staged transitions between cartilage and bone

28
Q

What is the main difference between intramembranous and endochondral ossification?

A

Presence of a zone of reversed cartilage in endochondral ossification that does not create any metabolic activity