Caries Formation Flashcards
What are the primary factors of caries? (4)
Host
Microbial flora
Substrate
Time
According to the modified keyes diagram what are the factors?
Primary modifying - oral environment
Secondary modifying - environmental factors
This is a layer that contains microorgranisms
Biofilm
What is an acquired pellicle?
if the plaque has no microorgranisms within them.
Biofilm is composed of? (4)
Bacteria
By-products
Extracellular matrix
Water
The microorganisms found in plaque are foreign. T or F
False, they are found in the normal oral flora
Streptococcus mutans are usually very adherent to the tooth structures especially in the _______ and __________
pits and fissure
mesial surface of the molars
Streptococcus mutans causes the biofilm to increase in _______, __________, _________, and _________
Carbon dioxide
Lactate
Acetate
Peroxide
The presence of streptococcus mutans causes the environment of the biofilm to become__________?
Anaerobic
Rapid _________ metabolism in the presence of ______________ forms acids
Anaerobic
suitable substrates
What is an important factor in mature biofilm?
Time
______________ byproducts causes the pH to drop
Metabolic
What are the critical pH of enamel and dentin respectively?
5.5 and 6.2
Low pH = _______
Demineralization
What are the indispensable factors of caries? (4)
Tooth
Substrate
Time
Biofilm
Which would dissolve faster in the presence of acids, Enamel or Dentin? Why?
Dentin, they only have 60-64% of HA crystals
What areas of the teeth are considered Caries Suceptible?
Pits and fissure
Proximal surfaces
CEJ
Lingual pits of lateral incisors
What areas of the teeth are considered Caries resistant?
Facial surfaces of the anterior teeth
Incisal edges of the anterior teeth
Cuspal tips of posterior teeth
Which are more susceptible to caries, Anteriors or Proximals? why?
Proximals because they are more exposed when we chew our food
These are shelters of the microorgranisms
Faults such as Pits and fissures
What is the composition of saliva?
Calcium and Phosphate ions
It is important to have a lot of saliva because?
Saliva aids in the mechanical washing of the tooth surfaces
The saliva should have what kind of viscosity?
Watery
This is when the calcium and phosphate ions leaves the tooth
Demineralization
This is when calcium and phosphate ions diffuses into the tooth
Remineralization
what does IAP stand for?
Ion activity product
KSP stands for?
Solubility Product Constant
SI stands for?
Saturation index
if SI is negative it means _________
there is demineralization occurring
ISP < KSP = SI is __________-
Negative
ISP > KSP = SI is ___________
what does the above mean?
SI is positive meaning there is no demineralization
What is the pH level of stimulated saliva?
7.4-7.8 pH
50% of stimulated saliva comes from __________ gland?
Parotid
There are _______ ions and ______ bicarbonates in stimulated saliva
More
What are the ions found in saliva?
Sodium
Chloride
Bicarbonate ions
Stimulated saliva is less ________ than unstimulated saliva
Hypotonic
What is the main buffer system?
Bicarbonates
what is the pH level of unstimulated saliva?
6.8-7.2 pH
The minor salivary glands produces _____ of the total saliva in the mouth?
10%
what is another gland that aids produces the unstimulated saliva other than the minor salivary glands?
Submandibular glands
Unstimulated saliva is more _________ than plasma
Hypotonic
A decrease in ions and an increase in potassium and phosphate indicates a _______ flow rate
low
There is an increase in ____,____, & ____ and a decrease in ____ and _____ in high flow rates of saliva
Na, Cl, HCO3
K and PO4
Which is more efficient in mechanical cleansing of the tooth surfaces, low flow rate or high flow rate?
High flow rate
Organic composition of saliva (6)
Digestive enzyme
Proteins with lubricating function
Ca binding proteins
Carbon dioxide hydration
Antimicrobial proteins
Growth factors
DPC CAG
The thicker the saliva the more prone the tooth is to _______________
Caries formation
Increase in buffer capacity, ________ caries formation
Less
This is the rate at which a substance is removed or cleared from the mouth or reduced to a very low concentration
Oral clearance rate
Oral clearance rate is dependent on?
Saliva flow rate
Volume of saliva before and after swallowing
What is the normal threshold of swallowing?
1.1 mL
What is the normal pH of the buffer capacity of saliva?
6 - 7.5 pH
Buffer capacity is determined by the lab through ___________
titration of saliva
Stimulated flow is the most _________
alkaline
What are the antimicrobial enzymes of saliva?
Lysozyme
Lactoperoxidase
Lactoferrin
Salivary peroxidase and thiocyanate
Immunoglobulins
Amylase
LLL SIA