Caries Causation Flashcards
Primary causal factor of dental caries?
Plaque
Plaque biofilm is the necessary and sufficient cause of dental caries.
False, it is not sufficient to cause dental caries but it is necessary.
Dental caries is a non-communicable __________ disease.
Bacteria-related
The responsible bacteria, and other micro-organisms, are located in a biofilm - ___________ - which adheres to tooth surfaces.
Dental plaque
When plaque bacteria are exposed to refined carbohydrates, especially ______, in the human diet, sucrose is ____________ by particular bacterial species.
Sucrose; fermented to acid
The acid is ______ against the tooth surface by the plaque biofilm and _____ through the enamel layer into dentine resulting in dissolution of the tooth mineral.
Trapped; diffuses
The Stephan curve describes ________ in plaque following exposure to sucrose or glucose.
pH changes
Describe the pH levels after exposure to glucose.
Plaque pH falls quickly following exposure to glucose and will rise back to its original value after 20 minutes or so, unless exposure continues.
What happens to enamel in sustained pH fall?
Enamel decalcification occurs.
What happens when pH returns to around 6?
Enamel calcification occurs; the decalcified enamel remineralises
What is this?
Stephan curve
Describe this graph/result
Duplicate curves of pH changes in plaque as measured by a microelectrode built into an extracted tooth on 2 days showing that the curves are reasonably reproducible.
Describe this curve
Effect of plaque pH of the local application of drops of 0.5% sugar solutions at 2-min intervals - note the marked response to low concentrations of sugar and the prolonged fall.
The sugar did not reach the tongue so that saliva flow was not stimulated - this result may, therefore, differ from the changes during normal eating when saliva flow is stimulated and the saliva probably reaches the plaque, but may resemble the changes in plaque when saliva cannot easily reach it as in fissures and inaccessible contact points.
Describe this figure
Effect of sugar rinse on the pH of plaque of different ages measured by microelectrodes built into an extracted tooth.
With the older plaques, the pH fall begins during the sugar rinse, reaches lower pH values and returns more slowly than with the 1-day-old plaque.
Mature 5-day plaque has the greater cariogenic potential. The pH dropped immediately rinsing commenced and remain depressed.
Which sites do carious lesions occur at?
Occurs at sites where mature plaque remains undisturbed - in fissure pits, between teeth on approximal surfaces, and along gingival margins.
Organic acids (the sucrose fermentation products) dissolve dental mineral in enamel (and at a later stage in dentine) known as _____, which is crystalline __________.
Apatite; calcium phosphate