Care of the Elderly Flashcards

1
Q

5 elements assessed in a comprehensive geriatric assessment

A

physical health
mental health
social aspects
functional aspects
environment

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2
Q

steps of a comprehensive geriatric assessment

A
  1. Assessment
  2. Stratified problem list
  3. Management plan
  4. Goals – then review
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3
Q

tools used for assessing ADL’s

A
  • Barthel index - 10 basic ADLs (Disabilities, bladder/bowels, grooming, toilet use, feeding, transfer, mobility, dressing, stairs, bathing)
  • Nottingham extended ADL scale - assesses instrumental ADLs (22 item)
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4
Q

inappropriate prescribing

A

Drugs which are contraindicated
Inappropriate dose/duration
Adversely affect prognosis
Not prescribing drug which is indicated

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5
Q

Risks of prescribing in older people

A
  • changes in pharmacokinetics and dynamics
  • polypharmacy and co-morbidity
  • frailty
  • cognitive/communication difficulties
  • lack of testing/evidence in older people
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6
Q

Physiological changes to pharmacokinetics/dynamics with aging

A
  • absorption (GI changes)
  • distribution - increased fat and decreased water (fat soluble drugs well distributed), low albumin
  • hepatic metabolism (reduced hepatic volume and enzymes)
  • renal elimination - reduced GFR
    TOXICITY
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7
Q

Geriatric Giants (6 I’s)

A

Incontinence, immobility, intellectual impairment, iatrogenesis, inanition, instability

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8
Q

Frailty diagnostic models

A
  • frailty phenotype Fried model (inintensional weight loss, weakness, exhaustion, slow walking, low level of activity
  • clinical frailty scale Rockwood (1 very fit - 9 end of life)
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9
Q

Physiological markers of frailty

A
  • Increased inflammation, insulin, glucose, and d-dimer
  • Decreased albumin and vitamin D
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10
Q

What is osteoporosis

A
  • progressive loss of bone mass
  • microarchitectural changes - reduced cross linking in trabecular bone with cortical thinning
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11
Q

Bone remodelling steps

A
  1. osteoclast activation (RANK-l bind with precursor cells)
  2. aggregation onto trabecular plate
  3. breakdown of bone
  4. simultaneous osteoblastic deposition of osteoid
  5. mineralisation with Ca and Pi
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12
Q

FRAX score

A
  • 10y risk of fracture (>10% need DEXA scan)
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13
Q

DEXA scan values

A

T-score (SD above/below BMD of average 25y/o)
< -2.5 osteoporosis
<-1 osteopenia

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14
Q

Management of osteoporosis

A
  • vit D and Ca
  • weight bearing exercise
  • HRT in early menopause
  • bisphosphonates (alendronate 10mg for 3-5y, anti-resorptive)
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15
Q

SE and measures taken when on bisphosphonates

A
  • oesophageal irritation - sit up for 30mins after and have water
  • osteonecrosis of the jaw - good dental hygiene
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16
Q

assessment for falls

A
  • > 2 in a year is significant
  • Assess cognition, vision, vestibular system, postural BP, CV system, proprioception, MSK, neuro and gait, footwear/walking aids
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17
Q

Investigations for falls

A

ECG, lying and standing BP
consider bloods including CK (from long lie muscle breakdown)

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18
Q

Complications from a long lie

A

pressure sores, rhabdomyolysis, dehydration, hypothermia, pneumonia

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19
Q

classification of dizziness

A
  • vertigo (spinning, vestibulo-labyrinthine system)
  • presyncope
  • unsteady (imbalance, abnormal sensory input)
  • psychogenic
  • mixed (frailty, multi-sensory dizziness syndrome)
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20
Q

Peripheral and central causes of vertigo

A
  • Peripheral causes = benign paroxysmal positional vertigo (BPPV), Meniere’s disease, vestibular neuritis, otitis media, aminoglycoside toxicity, acoustic neuroma
  • Central causes = migraine, brainstem ischaemia, cerebellar stroke, MS
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21
Q

manoeuvre for testing vertigo

A

Dix-Hallpike manoeuvre - causes ore severe vertigo and nystagmus

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22
Q

Benign paroxysmal positional vertigo

A

recurrent short episodes of vertigo
displacement of Ca crystals (otoliths) from inner ear to semi-circular canals

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23
Q

Meniere’s disease

A

30-50 y/o
recurrent vertigo lasting hours, tinnitus and fluctuations in hearing, progressive hearing loss
excess secretion of endolymph in canals

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24
Q

vestibular neuritis

A

sudden onset severe vertigo 2-3 days, nausea, spontaneous nystagmus
recent viral infection

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25
Q

causes of syncope (COR)

A
  • cardiac (arrhythmias, structural heart disease)
  • orthostatic hypotension (drug induced, primary autonomic failure (parkinsons etc), secondary autonomic failure (DM, spinal injuries etc), volume depletion)
  • reflex syncope (vasovagal, situational, carotid sinus syndrome)
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26
Q

Investigations for syncope

A

bloods, ECG, 24h tape, l&s BP

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27
Q

treatment of syncope

A

C - med review, cardiac pacing, surgery
O - med review, increase fluids, counter manoeuvres, compression stockings, fludrocortisone (mineralocorticoid to increase plasma volume)
R- counter manoeuvres

28
Q

stress incontinence (causes and management)

A
  • weakness of urinary outlet
  • caused by pelvic muscle damage
  • lifestyle measures (stop smoking, weight loss, less caffeine), Kegels, duloxetine, surgery
29
Q

Urge incontinence (causes and management)

A
  • failure to store urine dur to high bladder pressure
  • overactive bladder - urgency and urge
  • lifestyle changes, bladder training, kegels, anticholinergic (tolteridone), B3 adrenoceptor agonist (mirabegron), vaginal oestrogens, intradetrusor botox, sacral nerve stimulation
30
Q

Overflow incontinence

A

chronic urinary retention

31
Q

mixed incontinence

A

stress and urge

32
Q

Investigations for incontinence

A

urinalysis, mid-stream urine microscopy/culture/sensitivity, post-void bladder scan, bladder diary

33
Q

types of constipation

A
  1. High impaction caused by obstructive lesion
  2. Whole distal colon loaded with soft puffy like faeces
  3. Hard stool in rectum – faecal impaction may cause overflow diarrhoea
34
Q

Treatment of constipation

A
  • rehydration, mobilisation, high fibre diet, med review
  • stimulant laxatives - senna
  • softening laxatives - lactulose (need adequate fluid intake)
  • bulking laxatives - fybogel - fibre, can cause obstruction
  • enema or suppositories for rectal constipation
35
Q

Features of delirium

A

– acute onset, fluctuating, inattention, altered consciousness, medical cause

36
Q

types of delirium

A
  • Hypoactive – inactivity, abnormal drowsiness
  • Hyperactive – restlessness, mood changes, hallucinations
  • Mixed – switches back and forth
37
Q

pathogenesis of delirium

A
  • acetylcholine inhibition or pro-inflammatory cytokines
  • metabolic disturbance (hypoxia, hypoglycaemia)
38
Q

Causes/precipitating factors of delirium (DELIRIUM)

A

D – drugs
E – electrolyte imbalance
L – liver failure/ low oxygen
I – infection
R – retention (urinary/ faecal)
I – intracranial
U – uraemia
M- metabolic

39
Q

assessment of delirium

A

abbreviated mental test then confusion assessment method if <8/10

40
Q

investigations for delirium

A
  • First line – WCC, CRP, electrolytes, LFT, TFT, glucose, CXR, urinalysis, ECG
  • Second line – Ca, B12, folate, ABG, specimen cultures, CT head, toxicology screen, bladder scan, lumbar puncture
41
Q

management/prevention of delirium

A
  • treat cause
  • manage environment (orientation, good sleep)
  • monitor
  • haloperidol/lorazepam in severe distress in Lewy body dementia and parkinsons)
42
Q

Alzheimer’s disease

A
  • accumulation of Aβ amyloid and tau protein cause neuronal damage, neurofibrillary tangles, amyloid plaques, and loss of acetylcholine
  • particularly in hippocampus, amygdala, temporal neocortex and subcortical nuclei
  • AD genetic mutations for early onset
43
Q

Vascular dementia

A
  • caused by atherosclerosis or stroke in brain
  • subdivided into cortical vascular, subcortical vascular, post-stroke
44
Q

Mixed dementia

A

AD and VaD

45
Q

Lewy Body Dementia

A
  • Fluctuations in cognition, early visual hallucinations, and Parkinsonism (cognitive dysfunction presents within 2 years of motor features)
  • Lewy bodies build up in cortex and basal ganglia causing cellular loss
46
Q

frontotemporal dementia

A
  • changes in behaviour, emotion and language before memory is affected
47
Q

Examination for dementia

A

CV and neuro, MMSE

48
Q

Management of dementia

A
  • MDT, supportive care
  • Cognitive AD – acetylcholine esterase inhibitor (rivastigmine), anti-glutamate/NDMA antagonist (memantine)
49
Q

Total/partial anterior circulation stroke criteria

A
  • all 3 total, 2/3 partial: unilateral weakness, homonymous hemianopia, higher cerebral dysfunction
50
Q

lacunar syndrome stroke criteria

A

1 of: pure sensory, pure motor, sensori-motor, ataxic hemiparesis

51
Q

posterior circulation syndrome stroke classification

A

1 of: CN palsy with contralateral motor/sensory deficit, bilateral motor/sensory deficit, conjugate eye movement disorder (gaze palsy), cerebella dysfunction, isolated homonymous hemianopia

52
Q

investigations for stroke

A
  • FAST
  • Screen swallow (nil by mouth until this is done)
  • CT head
  • Bloods – FBC, U&E, ESR, TFT, glucose, clotting screen
  • ECG
  • Carotid doppler
53
Q

management of stroke

A
  • Protect airway and maintain homeostasis
  • Ischaemic stroke – IV alteplase within 4.5h of onset, aspirin 300mg 2 weeks then clopidogrel 75mg
  • Haemorrhagic – control BP to 140/90 (beta blocker), surgery (clot evasion)
  • Rehab – physio, OT
54
Q

features of parkinsonism

A
  • Bradykinesia – slow movements (finger to thumb test)
  • Rigidity – increased tone on movement, superimposed tremor (cog wheeling)
  • Tremor – resting, high amplitude, low frequency (pill rolling)
  • Postural instability
  • Micrographia
  • Abnormal gait – slow, shuffling, short steps, gets faster with momentum (festination)
  • Hypomimia – expressionless face
55
Q

types of parkinsonism

A
  • Parkinson’s disease – unilateral onset, upper limb predominance, treatment responsive, present with bradykinesia
  • Vascular parkinsonism – lower limb, bilateral onset, falls and gait problems
  • Drug-induced parkinsonism – antipsychotics
  • Lewy Body dementia – cognitive impairment with parkinsonism, hallucinations
  • Progressive supranuclear palsy – eye signs (vertical gaze palsy), cognitive impairment, no response to dopaminergic treatment
  • Multi-system atrophy – autonomic features (postural hypotension, incontinence, difficulty regulating temp), cerebellar signs, no response to treatment
56
Q

Parkinson’s disease

A

neurodegenerative disease, dopaminergic neuron loss and Lewy bodies concentrated in the substantia nigra – causes lack of dopamine

57
Q

treatment of Parkinson’s disease

A
  • dopaminergic drugs - co-careldopa first line (levodopa and carbidopa) - levodopa long term use causes dyskinesias
  • anticholinergic amantadine used to reduce tremor and dyskinesia
  • dopamine receptor agonist - pramiprexole
58
Q

clinical signs of poor nutrition and the specific deficiencies

A
  • Wernicke’s (vitamin B1/thiamine) – ataxia, confusion, coma, nystagmus
  • Anaemia (Fe, B12, folate)
  • Gingivitis (vit C)
  • Angular stomatitis, glossitis (vitamin B)
  • Koilonychia (Fe)
  • Bruising (vit C and K)
  • Proximal myopathy, bone pain, fractures (vit D)
  • Oedema (protein)
  • Muscle wasting (protein, calorie)
  • Polyneuropathy (vit B12, B1)
59
Q

malnutrition universal screening tool (MUST) steps

A
  1. Calculate BMI
  2. Note percentage of unplanned weight loss
  3. Establish acute disease effect and score
  4. Add scores from step 1-3
  5. Develop care plan (score >1 is high risk and need intervention)
60
Q

refeeding syndrome

A
  • fatal shifts in fluids/electrolytes with hormonal and metabolic changes when artificial feeding
  • hypophosphatemia (abnormal fluid balance, changes in metabolism, thiamine def, hypokalaemia, hypomagnesaemia)
  • at risk if without food for >5d
61
Q

treatment/prevention of refeeding syndrome

A
  • Give thiamine, vit B and multivitamin then start feeding, gradually increasing over 4-7 days, monitor fluids and electrolytes/vitamins closely and supplement if needed
62
Q

stages of pressure ulcers

A
  1. Non-blanching erythema – localised area over a bony prominence
  2. Partial thickness – loss of dermis, shallow open ulcer
  3. Full thickness – loss of subcut fat (bone, tendon, or muscle not visible)
  4. Full thickness – exposed bone, tendon, or muscle
63
Q

prevention of pressure ulcers (SSKIN)

A

S- support surface (beds/pressure mats)
S- skin assessment
K- keep moving
I- incontinence and moisture – assessments and management
N- nutrition and hydration

64
Q

advance statements

A

not legally binding but considered carefully

65
Q

lasting power of attorney

A

giving someone legal authority the make decisions about health, property and finances

66
Q

advanced decisions (living will)

A

legally binding, decisions to refuse specific medical treatment