Cardiovascular System (Part 2) - WEEK 2 Flashcards

1
Q

Which part of the cardiovascular system carries oxygenated blood away from the left ventricle to the body and returns ______________ back to the heart in right atrium?

A

Systemic Circulation, deoxygenated blood

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2
Q

Which circulation transports oxygen-poor blood from which chamber from the heart to the lungs. Which in result picks up ___________? What happens next afterwards.

A

Pulmonary circulation, right ventricle to the lungs, blood picks up new blood supply.

What happens next? Returns the oxygen-rich blood to the left atrium

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3
Q

What’s the percentage for systemic circulation?

A

84%

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4
Q

What is the percentage in Pulmonary circulation?

A

9%

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5
Q

When reading blood pressure, what are the values when reading systemic artery?

A

Systolic/diastolic = 120 mmHg / 80 mmHg

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6
Q

What is the name of this artery when systolic pressure is 25 mmHg and diastolic pressure is 8 mmHg?

A

Pulmonary artery

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7
Q

What is the systolic and diastolic pressures for hypertension?

A

140 mmHg / 90 mmHg

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8
Q

What are the 4 major pathways for capillary?

A

Diffusion, intercellular cleft/space, fenestration, transcytosis (caveolae)

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9
Q

What are components that are exchanged across the capillary vessel wall via 4 major pathways?

A

Nutrients, O2, CO2, metabolic waste products

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10
Q

In the volumes of the blood graph, which component takes the small percentage? what is the percentage?

A

Capillaries, 5%

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11
Q

With all the list of the structures of vascular walls, which vessel does not have smooth muscle?

A

Capillary

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12
Q

With all the list of the structures of vascular walls, which vessels contain endothelium?

A

All of the them contain endothelium in each vessel

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13
Q

Which blood vessel has a thicker wall? What about thin?

A

Thicker: artery
Thin: vein

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14
Q

Identify on which blood vessel usually has a low blood pressure?

A

Vein

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15
Q

In the concept of diffusion: lipid soluble substance, what are the two chemical substances that can diffuse directly through the cell membrane?

A

Oxygen and Carbon Dioxide

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16
Q

What substance can diffuse through the intracellular clefts? what type of cells are adjacent?

A

water-soluble, endothelial cells

17
Q

We all know that capillaries in the brain don’t have a fenestrae. So, what would it be called then?

A

nonfenestrated capillaries

18
Q

T/F All capillaries have a fenestrae

A

False. Not all capillaries have them

19
Q

Where is the transcytosis present of a cell?

A

Both endocytosis and exocytosis

20
Q

What is a caveolae?

A

They are vesicles in transcytosis of macromolecules across the endothelial cells

21
Q

T/F Caveolae substances are selective

A

True. Substances are selective

22
Q

What feature from the blood-brain barrier of the brain is enforced?

A

Astrocyte

23
Q

What are the features of the Artery?

A

High pressure and have thick smooth muscle

24
Q

What are the features of a Vein?

A

Have valves that prevent backflow of the blood & have a high compliance: increase volume = increase pressure

25
Q

Which blood vessel has a single layer endothelium and allows substances to exchange?

A

Capillary

26
Q

When you hear a patient that is diagnosed with Atherosclerosis, what do you think this is?

A

A build up plaque in the artery walls

27
Q

What occurred in the cause of Atherosclerosis? (4 reasons)

A

1) damage to endothelial cells induces inflammation
2) smooth muscle cells and Low-Density Lipoprotein (LDL) penetrates tunica intima
3) LDL attracts macrophages. Macrophages would engulf the fatty material. Cell becomes filled with lipids called Foam cells
4) Fibrous cap is formed. A fracture of plaque’s fibrous cap can cause Thrombosis

28
Q

What is the Top 10 causes of Death in the USA?

A

Heart Disease

29
Q

When is the development of atherosclerosis? (age period)

A

may begin in young adulthood

30
Q

When is a good time to prevent atherosclerosis?

A

within in adolescence and young adulthood

31
Q

What is Tight Junctions?

A

Impermeable junctions PREVENT molecules from passing through the intercellular space

32
Q

What is Desmosomes?

A

Anchoring junctions which bind adjacent cells together like a molecular “velcro” and help form an internal intension-reducing network of forces

33
Q

What are gap junctions?

A

communicating junctions allow ions and small molecules to pass for intercellular communication

34
Q

What are the 4 components that make up the structure of the vascular walls?

A

Endothelial cells, elastic fibers, smooth muscle, collagen fibers

35
Q

What type of component that has a rubber like material that accounts for most of the stretch of the vessels?

A

Elastic fibers

36
Q

Define Endothelial cells

A

cells that form a single continuous layer that lines all vascular segments

37
Q

What is the smooth muscle contain in the structure of vascular walls?

A

They are present in all blood vessels except capillaries & they exert tension by means of active contraction

38
Q

What is collagen fibers similar to?

A

fabric woven