Cardiovascular system Flashcards

1
Q

What is the order of the heart?

A

superior vena cava - RIGHT ATRIUM - Tricuspid valve - RIGHT VENTRICLE - pulmonary valve - PULMONARY ARTERY - lungs - LEFT ATRIUM - mitral valve - LEFT VENTRICLE - aortic valve - AORTA - body

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2
Q

What is diastole?

A

ventricle/atriums relax, filling with blood

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3
Q

What is systole?

A

ventricle/atriums contracting, realising blood

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4
Q

What does myogenic mean?

A

the heart beats itself, it creates its own signal

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5
Q

How is a heartrate created?

A
  1. sino-artial node (SAN) creates an electrical impulse
  2. causes atrial systole (contract)
  3. atriaventricular node (AVN) holds impulse for 0.1s - all blood fills ventricles
  4. impulse goes into the bundle of His and then goes into the purkinje fibres
  5. causes ventricular systole
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6
Q

stroke volume

A
  • volume of blood pumped out of the ventricles in each contraction (average 70ml)
  • stroke volume increases proportionally to work intensity and then plateus when sub-maximal exercise has been reached
  • stroke volume increases due to increased venous return and starlings law
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7
Q

cardiac output

A

the volume of blood pumped out by the hearts ventricles per minute

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8
Q

venous return

A

volume of blood returning to the right atrium via the veins, the greater the venous return the greater the stroke volume

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9
Q

the elasticity of cardiac fibres

A

the degree of stretch of cardiac tissue during the diastole phase of cardiac cycle, greater the stretch greater the force

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10
Q

What is starlings law?

A

increased venous return means more blood enters the ventricles during the diastolic phase which causes more stretch and then they contract more forcefully (an elastic band)

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11
Q

ejection fraction equation

A
  • ejection fraction = stroke volume / diastolic volume
  • average is 60% but goes to 85% during exercise
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12
Q

the contractility of cardiac tissue (myocardium)

A

increased contractility allows greater force which increase the stroke volume

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13
Q

maximal heartrate

A

220-age=max heartrate

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14
Q

anticipatory rise

A

prior to exercise heartrate increases due to the hormone adrenaline being realised

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15
Q

cardiac hypertrophy

A

when regular aerobic exercise causes te cardiac muscles to get bigger and stronger

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16
Q

steadystate exercise

A

when the oxygen demands are met by the oxygen supply

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17
Q

cardiovascular drift

A
  • occurs during prolonged exercise (10 mins in a warm enviroment)
  • due to sweating (portion of plasma)
  • this reduces venous return and stroke volume
  • to minimise you need a high fluid consumption
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18
Q

stroke volume in a trained athlete

A
  • resing stroke volume - 80-110ml
  • submaximal exercise - 160-200ml
  • maximal exercise - 160-200ml
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19
Q

stroke volume in an untrained person

A
  • resting stroke volume - 60-80ml
  • submaximal exercise -100-120ml
  • maximal exercise - 100-120ml
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20
Q

cardiac output on a trained athlete

A
  • resting - 5L/min
  • submaximal exercise - 15-20L/min
  • maximal exercise - 30-40L/min
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21
Q

cardiac output in an untrained person

A
  • resting - 5L/min
  • submaximal exercise - 10-15L/min
  • maximal exercise - 20-30L/min
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22
Q

what controls the cardiac control centre?

A

autonomic nervous system

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23
Q

conduction system

A

controls the cardiac cycle

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24
Q

what determins the rate at which cardiac impulses are fired?

A
  • neural control
  • hormonal control
  • intrinsic control
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25
Q

proprioceptors

A
  • detect an increase in muslce movement
  • located in muslce tendons and joints
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26
Q

chemoreceptors

A
  • detect increase in lactic acid and carbon dioxide levels
  • located in medulla oblongata
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27
Q

baroreceptors

A
  • detects an increase in blood pressure
  • located in blood vessels
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28
Q

intial factors that effect our heart rate

A
  • temperature increase
  • decrease in blood viscosity
  • venous return
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29
Q

after exercise what factors occur

A
  • temperature decrease
  • heartrate decrease
  • venous return decrease
  • stroke volume decrease
30
Q

bradycardia

A

resting heartrate under 60bpm

31
Q

heart disease - ATHEROSCLEROSIS

A
  • blood vessels going towards the heart start to narrow due to atheroma (fatty deposits)
32
Q

what causes atherosclerosis?

A
  • high blood pressure
  • high cholesterol levels
  • lack of exercise
  • smoking
33
Q

heart disease - ANGINA

A
  • when the arteries narrow they are unable to carry oxygen and this causes discomfort (angina)
  • if a peice of atheroma breaks off it can cause a blood clott which leads to a heart attack
34
Q

how to fix atherosclerosis and angina

A
  • exercise helps to keep heart healthy
  • more blood can be pumped through - bigger heart
  • blood vessels become more flexible - ensures good blood flow
35
Q

High blood pressure

A
  • high blood pressure put extra strain on the artery walls
  • can cause a heart attack, heart failure, kidney disease, stroke or dementia
36
Q

how to solve high blood pressure?

A
  • regular aerobic exercisecan reduce blood pressure
  • lowers systolic and diastolic pressure whihc reduces a heart attack
37
Q

cholestrol levels - LDL

A
  • low density lipoprotein transports cholestrol in the blood
  • doesnt break it down
  • “bad”
38
Q

cholestrol levels - HDL

A
  • high density lipoprotein that transports excess cholestrol back to the liver
  • gets broken down
  • lower the chance of a heart attack
39
Q

how to solve bad cholerstrol

A

regular aerobic exercise decreases LDL and increases HDL which decreases chance of heart attack

40
Q

strokes

A
  • occurs when blood suplly to the brain is cut off
  • can lead to brain injury, disability and death
41
Q

ischaemic stroke

A

occurs when a blood clot stops blood supply

42
Q

haemorrhagic stroke

A

occurs when a weakened blood vessel supplying to the brain bursts

43
Q

how to solve stroke

A

regular exercise lowers blood pressure and maintains healthy weight

44
Q

what are the two tyoes of curculation?

A
  • pulmonary circulation
  • systemic circulstion
45
Q

arteries/arterioles

A
  • transport oxygnated blood away from the heart
  • large middle layer of smooth muscle (allows to vasodilate/vasocontrisct)
46
Q

cappillaries

A
  • fit one cell thick
  • slows down the speed of blood
  • allows nutrients to diffuse
47
Q

veins/venules

A
  • transports deoxyganted blood back to the heart
  • pocket valves to prevent backflow
  • thin walls which allow venocontrict/venodialte
  • thick outlayer which supports valves
48
Q

blood pressure

A
  • expressed as systolic (highest) / diastolic (lowest)
  • average 120mmHg / 80mmHg
  • blood pressure = blood glow (cardiac output) X restistance (friction)
49
Q

blood pressure during endurance training

A
  • increase in cardiac output cause BP to increase
  • viscosity increase
50
Q

what happens to systolic Bp during endurance training?

A
  • increases in line with intensity
  • plateau during sub-maximal exercise
  • decrease gradually if the intensity is prolonged
  • if intensity increases it will continue to with exercise
51
Q

what happens to diastolic Bp during endurance training?

A
  • changes little during submaximal exercise
  • gross muscle activity Bp may fall
  • Bp may increase a tiny bit when maximal exercise is reached
52
Q

pulmonary circulation

A

deoxygentated blood goes from the heart to thr lungs to get oxygentaded and then back to the heart

53
Q

systemic circulation oxygenated

A

oxyganted blood goes from the heart to the body and then deoxyganted blood goes back to the heart

54
Q

blood pressure

A

the pressure exerted by the (aterial) blood vessel walls

55
Q

what happens to blood pressure during isometric/restistance training

A
  • blood vessels are blocked by sustained stactic muscle contractions
  • restrict blood flow through aterial and venous which increase vascular resistance
56
Q

what happens during post exercise recovery?

A
  • systolic Bp decreases temporarily up to 12hrs
  • diastolic Bp stays low
57
Q

hypertension

A
  • prolonged high blood pressure
  • high is 140/90
58
Q

harmful effects of hypertension

A
  • increased workload on heart
  • increasing atherosclerosis
  • increasing arteriosclerosis
  • arterial damage
  • congesive heart failure
59
Q

isometric work

A

muscle contracts but no movement occurs

60
Q

increased workload on heart

A

increased resistance to expel blood

61
Q

increased atherosclerosis

A

hardening of the arterial walls

62
Q

the venous return mechanism

A

transport of blood from the cappilaries though venules, veins and then either to the supiror or infiror vena cava back to the righ atrium

63
Q

distribution of cardiac output at rest and during exercise

A
  • vascualar shunt mechanism - redistrobution of blood
  • at rest 15-20% supplied to muscles and 80-85% to organs
  • 80-85% goes to muscles during exercise however brain is maintained
  • blood supply to skin surface decreases
64
Q

where is the vascomotor control centre?

A

the medulla oblangata

65
Q

what does the vasomotor control centre reicve?

A

messages from chemoreceptors and baroreceptors

66
Q

what happens to organs during exercise?

A

the vasomotor control centre decreases the sympathatic stimulations which vasodilates arteries - more blood flow

67
Q

importance of redistribution of blood

A
  • increased oxygen supply to muslces
  • remove waste products
  • ensure more blood flow to skin to regulate body temp
  • more blood to heart
68
Q

sympathatic nervous system

A
  • the vasomotor control centre only sends messages via the sympathatic ns
  • the arterioles are the blood vessels that are primarly responsable for the vasculr shunt system
  • always in the state of slight contraction
69
Q

venous return mechanisms

A
  • pocket valve - prevent backflow by shutting when heavy, open when new rush
  • muscle pump- muscles contract and relax they press on nearby veinsand squeezes blood back to heart
  • repiratoty pump - - muscles contract causing pressure change in abdominals and thoracic - press on nearby veins
  • smooth muscle - thin layer of muslce that squeezes blood back
  • gravity - blood coming from head
  • suction pump - fluid runs through vein natrually pulls more fluid
70
Q

oxyhaemoglobin dissociation

A
  • is when oxygen goes from oxyhaemoglobin to muscles
  • during exercise - 3% oxygen goes to plasma, 98% combines with haemoglobin
  • carries 4 oxygen molecules
  • occurs when partial pressure in the blood is high
  • oxygen is stored in myoglobin - higher affinity for oxygen
71
Q

bohr shift

A
  • as partial pressure of oxygen drops in the tissues - Co2 increased partial pressure - blood becomes acidic
  • diffusion gradient becomes bigger - oxygen is realised from haemoglobin quicker
  • when body is warmer blood is less viscous
  • 3 factors that increase dissociation;
    1. increase in blood temp - blood and muscles temp increase, oxygen will dissociate quickly
    2. partial pressure co2 increases - dissocate quicker
    3. pH - co2 lowers pH in blood, dissociate quicker (bohr shift)
72
Q

arterio-venous difference (A-VO2)

A
  • the difference between the oxygen content of the arterial blood arriving at the muscle and the venous blood leaving the muscles
  • during exercise there is a bigger difference between the volume of oxygen going into the muscles than coming out of the veins compared to at rest - less of a difference
  • trained athletes have more myoglobin so they will have a greater difference