Cardiovascular system Flashcards
The principal neurotransmitter in the parasympathetic nervous system is:
Acetylcholine
Atenolol is a:
Beta 1-receptor antagonist
In G-protein coupled receptor signal transduction, protein kinase A is typically activated by
Cyclic AMP
What type of enzyme is angiotensin-converting enzyme?
Carboxypeptidase
What type of protein is the nicotinic acetylcholine receptor?
Ligand-gated ion channel
The enzyme angiotensin converting enzyme contains which metal ion within its active site that is pivotal to the conversion of angiotensin I to angiotensin II?
Zinc (II)
Which of the following is a partial agonist?
Oxprenolol
Myasthenia gravis results from:
Reduced population of nicotinic acetylcholine receptors on postsynaptic cell
What is the principal physiological effect of hydrochlorothiazide?
Reduces blood volume
What type of protein is the glucocorticoid receptor?
Steroid hormone receptor
Botulinum toxin reduces transmission at the neuromuscular junction by which of the following mechanisms?
Inhibiting fusion of vesicles with nerve terminal membrane
Which of these terms is defined by the following? “The ability of a drug to bind to a receptor”.
Affinity
Betablockers should not be prescribed to a patient with which disorder?
Asthma
Which type of molecular interaction does an irreversible antagonist have with its receptor that a reversible antagonist does not?
Covalent bonds
Hydrochlorothiazide should not be prescribed to a patient with which disorder?
High cholesterol levels
