Cardiovascular System Flashcards
What is the role of plasma?
Transports dissolved substances
What is the role of erythrocytes (RBC’s)?
Carries oxygen and some carbon dioxide
What is the role of leukocytes (WBC’s)?
Helps destroy bacteria
What is the role of thrombocytes (platelets)?
Triggers blood clotting
What are antibodies?
Proteins made by the immune system
What is urea?
Poisonous waste product from protein
What do leukocytes (WBC’s) contain?
Neutrophils - b-type cells that produce antibodies
Lymphocytes - t-type cells that destroy viruses and cancer cells
Monocytes - remove dead cells and bacteria
Where does blood transport materials?
Either erythrocytes (RBC’s) or plasma
What do erythrocytes (RBC’s) have?
Iron-containing protein called haemoglobin
What substances dissolve in plasma?
Glucose, amino acids and hormones
What is the body made of and what does it do?
Millions of chemical reactions which are regulated by enzymes
Produces heat, eg muscle tissues
What must the core temperature of the body be?
37 degrees celsius
Why can the core temperature not be any more or less?
The enzymes breakdown ‘denature’ at high temperatures, and slow down at low temperatures
What happens if it is too hot?
The skin blood vessels widen (vasodilate) and lose heat
What happens if it is too cold?
The skin blood vessels narrow (vasoconstrict) and save heat
How can you exchange materials in body tissues?
Using your cardiovascular system
How do materials exchange?
Between blood and tissues by diffusion
Define diffusion
When you go from a high concentration to a low concentration
How many litres of blood do we have (estimated)?
5 litres
If you lose _ litres it may lead to death.
2
How do platelets help broken skin heal and prevent pathogen access?
Convert soluble fibrinogen -> insoluble fibrin -> process called coagulation (turning liquid to gel)
This then forms a net-like structure -> traps platelets and erythrocytes (RBC’s) -> forms clot and seals broken skin
What is the reason of erythrocytes (RBC’S) being small?
It lets red blood cells pass through narrow capillaries
What is the reason of erythrocytes (RBC’s) having a flattened disc shape?
It provides a large surface area, which allows rapid diffusion of oxygen
What is the reason of erythrocytes (RBC’s) containing haemoglobin?
Haemoglobin absorbs oxygen in the lungs and releases oxygen in the rest of the body
What is the reason of erythrocytes (RBC’s) not containing a nucleus?
It increases the amount of space inside of the cell for haemoglobin
What is atheroma (atherosclerosis)?
This is when the walls of the coronary arteries become blocked with fatty deposits - a process called atherosclerosis
What are the symptoms of angina?
Breathlessness, nausea, dizziness, chest pain/tightness - can spread to arms, neck and jaw
How do heart attacks (myocardial infarction) happen?
When the arteries become completely blocked, it can lead to a heart attack which can permanently damage the heart muscle and lead to death
3 types of CHD (Coronary Heart Disease)
Atheroma
Angina
Heart attack
Risk factors for CHD
Increasing age
Family history
Lack of exercise
High dietary salt intake
Being overweight/obese
Smoking and alcohol
What medications can help atheroma?
Statins - cholesterol lowering medicine
What medications can help angina?
Nitrates - relaxes the coronary arteries, which allows more blood to reach the heart muscle
What medications can help a heart attack?
ACE inhibitors - lowers blood pressure, making heart attacks less likely
Aspirin - an anti platelet medicine which makes blood less likely to clot, reducing risk of heart attack
What monitoring/treatment can you get for CHD?
Angiogram - type of x-ray where dye is injected into the blood so narrowing of coronary arteries can be seen
Angioplasty - a microscopic deflated balloon is passed into the narrowed artery and inflated to push it open (sometimes microscopic mesh tube ‘stent’ is inserted to keep artery open)
Coronary bypass - using a piece of artery taken from somewhere in the body to bypass/bridge a blocked region of coronary artery (allows blood to flow beyond blockage)
What are the pros and cons of coronary bypass?
Pros -
• 2-3 days in hospital
• small incision in wrist/thigh - therefore low risk of infection
Cons -
• long healing process (several months)
• can’t drive for 6 weeks
What are the pros and cons of angioplasty?
Pros -
• can drive the next days
Cons -
• doesn’t always work
• may need several procedures
What does a blood test inform an individual on linked to CHD?
Can detect LDL/HDL cholesterol and proteins in blood
What does an ECG scan inform an individual on linked to CHD?
Analyses functioning of the heart from electrical signals
What does an angiogram inform an individual linked to CHD?
Pinpoints blockages to coronary arteries by using dye in x-ray
What does a BP test inform an individual linked to CHD?
The readings indicate raised levels and risk of hypertension damage
What is an ideal blood pressure rating?
Up to 120/80mmHg
What simple measures could an individual take to minimise the possibility of developing heart disease/experiencing a stroke?
- Exercise more frequently - lack of exercise is a CHANGEABLE factor and ensures they raise their heartbeat regularly and keeps blood pressure at an ideal rating - also helps lose weight and lower blood pressure
- Reduce fat in diet - reduces risk of atheroma
- Stop smoking - reduces pressure and prevents damage to arterial walls
- Reduce alcohol intake - lowers pressure and reduces weight
- Reduce stress
What 2 numbers is blood pressure recorded with?
- Systolic pressure - when your heart pumps around the body (higher number)
- Diastolic pressure - when it is filling showing the resistance of the blood in the blood vessels (lower number)
What damages blood vessels?
Prolonged high blood pressure