Cardiovascular Part 7 Flashcards
What is the maximum simvastatin dose with ticagrelor 90mg tablets?
Simvastatin 40mg
What is the maximum simvastatin dose with amlodipine?
Simvastatin 20mg
What is the maximum simvastatin dose with ranolazine MR 375mg tablets?
Simvastatin 20mg
What are the administration instructions for perindopril?
Take 30-60 minutes before food
Which antihypertensive, if stopped abruptly, can cause rebound hypertension?
Clonidine hydrochloride
Which co-morbidity is least likely to co-exist with heart failure?
Asthma
What is the clinic reading for stage 3 hypertension?
180/120 mmHg
Which thiazide diuretic is least likely to cause hypokalemia?
Indapamide - causes hypokalaemia
What are the side effects associated with indapamide?
Hyponatraemia
Hypokalaemia
Cardiac arrhythmias
May increase blood glucose
May increase LDL
Impotence in men
What is the dose for bendroflumethiazide for hypertension and oedema?
Hypertension: 2.5mg OD
Oedema: 5mg OD
What is the maximum dose of simvastatin with amiodarone?
Simvastatin 20mg
What is the maximum simvastatin dose with amlodipine and diltiazem?
Simvastatin 20mg
Which drug causes nightmares and sleep disturbances?
Propranolol
What is an important MHRS warning for Hydrochlorothiazide?
Can cause non-melanoma skin cancer, particularly in long-term use
- Seek medical attention
What is the general serum creatinine for a healthy male?
84-110 micromol/L
What is the risk of furosemide in pregnancy?
hypovolaemia
What is the interaction between statins and macrolides?
Risk of rhabdomyolysis
What is the interaction between gentamicin and loop diuretics?
Risk of renal failure
What is the interaction between ACEi and potassium-sparing diuretics?
Hyperkalaemia risk
What is the interaction between ACEi and metformin?
Enhance hypoglycaemic effect
