Cardiovascular Part 1 Flashcards
Systemic loop
carries oxygenated blood from the heart to the rest of the body
Pulmonary loop
carries oxygen-poor blood to the lungs and back to the heart
Epicardium
Superficial
Visceral serous membrane
Myocardium
Middle
Mostly cardiac muscle, most of heart
Endocardium
Inner
Lines heart chambers
Heartbeat Coordination
The sinoatrial (SA) node (pacemaker)
generates impulses.
The impulses pause (0.1 sec) at the
atrioventricular AV) node.
The atrioventricular (AV) bundle
connects the atria to the ventricles.
The bundle branches conduct the impulses through the interventricular septum.
The Purkinje fibers stimulate the contractile cells of both ventricles.
Pacemaker potential
Initial depolarization by Na+ entry
Further depolarization to threshold by Ca2
Repolarization by K+ exit
4 voltage gated channel
F-type (funny)
* Open when membrane potential is negative
* Na+ enters
- T-type (transient)
- Ca2+ channel
- Brief entry of Ca2+
- To threshold
- L-type (long-lasting)
- Ca2+ channel
- Rapid entry of Ca2+
- To peak of AP
- K+ Channels
- K+ exits
- Repolarization
Depolarization causes
contraction of myocardial
cell via
Ca2+
PSNS
innervates the node cells
releases ACh that binds muscarinic AChR
SNS
innervates the entire myocardium and node cells
releases NE that binds β-adrenergic receptors