Cardiovascular Medicine - Lower Cholesterol Flashcards
How they work
Reduce the body’s
ability to make
cholesterol or enhance
pathways for
elimination in the
hopes that it reduces
the risk of
cardiovascular events
What they
are used for
Treat high cholesterol
and lower the risk of
heart attacks and
strokes
Drug Classes
HMG-CoA Reductase
Inhibitors (statins)
•Fibric acid derivatives
•Miscellaneous
Possible Side Effects
Gastrointestinal
upset/nausea, muscle
pain (myalgia), liver
toxicity
HMG-CoA Reductase Inhibitors (Statins)
Common Indicator: Hypercholesterolemia
Side effects: myalgias and rhabdomyolysis
Drug classes:
Lipitor (atorvastatin)
Lescol (fluvastatin)
Mevacor (lovastatin)
Pravachol (pravastatin)
Crestor (rosuvastatin)
Zocor (simvastatin)
Fibric Acid Derivatives (Fibrates)
Common Indicator: hypercholesterolemia
Side effects: myalgias and rhabdomyolyisis
Drug classes: Tricor (fenofibrate)
Trilipix (fenofibric acid)
Lopid (gemfibrozil)
Miscellaneous Drugs that Modify the Cholesterol
Common Indicator: hypercholesterolemia
Side Effects: Gastrointestinal
Drug classes: Zetia (ezetimibe)
Vytorin (ezetimibe/simvastatin)
Lovaza (omega-3 fatty acids)
Niaspan (niacin)
Erythropoiesis Stimulating Agent
Common Indicator: Anemia
Side Effect: blood clot cancer
Drug classes: Aranesp (darbepoetin)
Procrit (epoetin alfa)