Cardiovascular Medicine - Lower Cholesterol Flashcards

1
Q

How they work

A

Reduce the body’s
ability to make
cholesterol or enhance
pathways for
elimination in the
hopes that it reduces
the risk of
cardiovascular events

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2
Q

What they
are used for

A

Treat high cholesterol
and lower the risk of
heart attacks and
strokes

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3
Q

Drug Classes

A

HMG-CoA Reductase
Inhibitors (statins)
•Fibric acid derivatives
•Miscellaneous

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4
Q

Possible Side Effects

A

Gastrointestinal
upset/nausea, muscle
pain (myalgia), liver
toxicity

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5
Q

HMG-CoA Reductase Inhibitors (Statins)

A

Common Indicator: Hypercholesterolemia
Side effects: myalgias and rhabdomyolysis
Drug classes:
Lipitor (atorvastatin)
Lescol (fluvastatin)
Mevacor (lovastatin)
Pravachol (pravastatin)
Crestor (rosuvastatin)
Zocor (simvastatin)

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6
Q

Fibric Acid Derivatives (Fibrates)

A

Common Indicator: hypercholesterolemia
Side effects: myalgias and rhabdomyolyisis
Drug classes: Tricor (fenofibrate)
Trilipix (fenofibric acid)
Lopid (gemfibrozil)

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7
Q

Miscellaneous Drugs that Modify the Cholesterol

A

Common Indicator: hypercholesterolemia
Side Effects: Gastrointestinal
Drug classes: Zetia (ezetimibe)
Vytorin (ezetimibe/simvastatin)
Lovaza (omega-3 fatty acids)
Niaspan (niacin)

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8
Q

Erythropoiesis Stimulating Agent

A

Common Indicator: Anemia
Side Effect: blood clot cancer
Drug classes: Aranesp (darbepoetin)
Procrit (epoetin alfa)

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