Cardiovascular Histology Flashcards

1
Q

2 circulatory systems

A

cardiovascular symptom

lymphatic vascular systems

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2
Q

cardiovascular system

A

closed system

heart, arteries, capillaries + veins

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3
Q

roles of cardiovascular system

A

transport of O2 + nutrients to tissues
transport of CO2 + other metabolic waste from tissues
temperature regulation
distribution of hormones + immune cells
reproductive function in males = penile erection

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4
Q

where is blood in body

A

peripheral veins (65%)
heart + lungs (20%)
peripheral arteries (10%)
capillaries (5%)

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5
Q

blood vessel layers

A
inner = tunica intima
middle = tunica media
outer = tunica adventitia
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6
Q

tunica intima

A

endothelial cells

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7
Q

tunica media

A

smooth muscle

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8
Q

tunica adventitia

A

supporting connective tissue

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9
Q

tunica intima = separated from tunica by

A

internal elastic membrane

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10
Q

tunica media = separated from tunica adventitia by

A

external elastic membrane

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11
Q

largest arteries

A

elastic arteries

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12
Q

elastic arteries = own vascular supply

A

vasa vasorum

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13
Q

role of arterioles

A

controlling blood flow in tissues

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14
Q

what are capillaries composed of

A

endothelial cells + basal lamina

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15
Q

what are pericytes

A

outside basal lamina
connective tissue cells
contractile properties

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16
Q

3 types of capillary

A

continuous capillaries
fenestrated capillaries
sinusoidal or discontinuous capillaries

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17
Q

continuous capillaries location

A
muscle
connective tissues
lung
skin
nerve
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18
Q

fenestrated capillaries location

A

mucosa of gut
endocrine glands
glomeruli of kidney

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19
Q

sinusoidal or discontinuous location

A

liver
spleen
bone

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20
Q

capillary networks drain into

A

post capillary venules

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21
Q

what are post capillary . venules

A

endothelial cell lined + thin layer of connective tissue + occasional pericytes

22
Q

importance of post capillary venules

A

exchange

cells moves into tissue for inflammation

23
Q

largest veins

A

vena cava/ hepatic portal vein

24
Q

veins flexibility characteristic

A

accomodate expansion

contain most of blood

25
3 layers of heart
``` endocardium = inner layer myocardium = middle layer epicardium = outer layer ```
26
endocardium
inner surface endothelial cells fibrous tissue cardiac muscle
27
subendocardium
endothelial cells fibrous tissue cardiac muscle purkinjie fibres
28
myocardium
thick middle layer bundle + layers of contractile cardiac fibres individual muscle fibres = delicate, collagenous connective tissue + rich network of capillaries
29
epicardium
outer layer flattened epithelium = mesothelium basal lamina fibroelastic connective tissue
30
2 parts of pericardium
fibrous pericardium | serous pericardium
31
fibrous pericardium
tough fibrocollagenous connective tissue
32
serous pericardium
simple squamous epithelium basal lamina connective tissue
33
parietal serous pericardium
serous pericardium lines inner surface of fibrous pericardium
34
visceral serous pericardium
serous epicardium covers heart surface
35
how is the fibrous skeleton of the heart formed
thick bands of fibrous connective tissues around heart valves between atria + ventricles
36
connective tissue of heart
supports valves | attachment for cardiac muscle fibres
37
heart valve structure
``` outer endothelial layer + basal lamina collagen + elastin fibres layer core dense connective tissue = lamina fibrosa papillary muscles chordae tendineae ```
38
do the valves contain blood vessels
no blood vessels
39
lamina fibrosa
heart valve core dense irregular connective tissue continuous with fibrous skeleton covered both sides by endothelium
40
types of cardiac muscle
contractile cells pacemaker cells conducting cells
41
pacemaker cells
``` highly specialised muscle cells appear pale few myofibrils little glycogen no proper T-tube system ```
42
sequence of events from junction of atria
``` junction of atria AV node picks up depolarisation delay then rapid interventricular septum atrioventricular bundle left + right bundle branches = downwards reach inferior tip = upwards Purkinjie fibres ```
43
fibrous skeleton role
physical support | electrically isolates atria from ventricles
44
purkinjie fibres
``` larger than normal cardiac muscle cells found = subendocardial layer abundant glycogen no T-tubules no intercalated discs sparse actin + mysin filaments = periphery pale celar centre ```
45
purkinjie fibres role
distribute excitatory activity e.g. ventricular contraction
46
what is the lymph vascular system made up of
lymphatic vessels that drain tissue fluid - eventually returning it to veins in base of neck
47
blind sacs develop into
lymphatic capillaries
48
what does interstitial fluid contain
ions lipids proteins occasional cells
49
lymph passes through lymph nodes for
immunological surveillance
50
what produces flow in lymphatic vessels
no central pump | SM in walls, hydrostatic pressure in tissues + compression of vessels by voluntary muscles