Cardiovascular Drugs Indications

Question 1

Fibrates

Answer 1

High cholesterol

Question 2

Statins

Answer 2

High cholesterol

Question 3

Nitrates

Answer 3

Angina

Question 4

B-adrenoreceptor antagonists

Answer 4

Angina, reduce risk of death post-MI, heart failure, hypertension, IHD, atrial fibrillation

Question 5

Calcium channel blockers

Answer 5

smooth muscle = hypertension, cardio = atrial fibrillation, supraventricular tachycardia, angina

Question 6

COX inhibitors

Answer 6

prophylactic anti-platelet. Reduce risk of thrombus formation

Question 7

P2Y12 inhibitors

Answer 7

prophylactic anti-platelet. Reduce risk of thrombus formation

Question 8

Thrombin-receptor antagonist

Answer 8

prophylactic anti-platelet. Reduce risk of thrombus formation

Question 9

IV Heparin (Anticoagulant)

Answer 9

thromboembolic disease (unfractionated heparin used only with renal failure, or with high risk of bleeding)

Question 10

Warfarin (Anticoagulant)

Answer 10

thromboembolic disease: atrial fibrillation, artificial heart valves, DVT, Pulm embolism, antiphospholipid syndrome, (MI)

Question 11

Rivaroxaban (Anticoagulant)

Answer 11

DVT and PE, prevention of cardioembolic events in patients with AF, benefits over warfarin

Question 12

Fibrinolytic

Answer 12

given within 12 hours of MI

Question 13

Cardiac Glycoside

Answer 13

heart failure with rapid atrial fibrillation, or last resort after ACE inhabit and diuretics. Acute heart failure.

Question 14

Loop diuretics

Answer 14

chronic heart failure

Question 15

Aldosterone Receptor Antagonists

Answer 15

chronic heart failure

Question 16

ACE inhibitors

Answer 16

chronic heart failure, post MI

Question 17

Angiotensin II receptor blockers (ARBs)

Answer 17

Chronic heart failure, hypertension

Question 18

Vasodilators

Answer 18

acute heart failure/chronic but fail to respond to other drugs

Question 19

Thiazide diuretics

Answer 19

mild heart failure, severe resistant oedema, uncomplicated hypertension, elderly patients

Question 20

Purine nucleoside

Answer 20

supra-ventricular tachycardia (inc. diagnosis)

Question 21

Membrane-stabilising anti-arrhythmic

Answer 21

ventricular tachycardia (post MI vent arrhythmias), local anaesthetic

Question 22

Class 3 anti-arrhythmic

Answer 22

Ventricular tachycardia, multipurpose antiarrhythmic, atrial and ventricular

Question 23

Muscarinic antagonist

Answer 23

complete heart block, sinus bradycardia

Question 24

Potassium channel openers

Answer 24

Hypertension

Question 25

Alpha-adrenoreceptor blockers

Answer 25

Hypertension