CARDIOVASCULAR DRUGS Flashcards
What are the functions of Circulatory system?
1) delivery of oxygen, nutrients, hormones, electrolytes, and other essentials to cells and
2) removal of carbon dioxide and metabolic wastes from cells. In addition, the system helps fight infection
The circulatory system is composed of?
The heart is the pump that moves blood through the arterial tree.
• Arteries transport blood under high pressure to tissues.
• Arterioles are control valves that regulate local blood flow.
• Capillaries are the sites for exchange of fluid, oxygen, carbon dioxide, nutrients, hormones, and wastes.
• Venules collect blood from the capillaries.
• Veins transport blood back to the heart. In addition, veins serve as a major reservoir for blood.
Define hypertension
Defined as a persistent systolic pressure of greater than 140mmHg and/or a diastolic pressure of greater than 90mmHg
What is the goal OF ANTIHYPERTENSIVE THERAPY?
- Reduction of Cardiovascular and morbidity and mortality
- Individualized considering co- morbidities and impact of patient’s quality of life
What is Diuretics?
Drugs that accelerate the rate of urine formation that results to the removal of sodium and water from the body
What is adrenergic drugs?
Central Acting – acts on the brain by decreasing NE production
Drugs: Clonidine, Methyldopa
Peripheral Acting – at the heart and blood vessels
Drugs: Alpha and Beta Blockers
What are angina types?
Chronic Stable Angina
Unstable Angina
Vasospastic Angina
What is ANTI-ANGINAL DRUGS?
- Nitrates and Nitrites
- Beta Blockers
- Calcium Channel
Blockers
What is beta blockers?
Most effective treatment of exertional angina
Approved for treatment of MI, hypertension, cardiac dysrhythmias and essential tremor.
NITRATES AND NITRITES
Mainstay prophylaxis and treatment for angina
