ANTIBIOTIC DRUGS

Question 1

What is prokaryotes?

Answer 1

• Also known as bacteria which are single called organisms that lack a true nucleus and nuclear membrane.
• it has a cell wall that determines its shape.

Question 2

What are the five mechanisms of antibacterial action?

Answer 2

1. inhibition of bacterial cell-wall synthesis
2. alteration of membrane permeability
   3.inhibition of protein synthesis
3. inhibition of the synthesis of bacterial RNA and DNA
   5.interference with metabolism within the cell

Question 3

What happens when the bacteria is sensitive to the drug?

Answer 3

• the pathogen can be inhibited or destroyed

Question 4

What happens when bacteria is resistant to the drug?

Answer 4

• the pathogen will continue to grow despite administration

Question 5

Types of resistance?

Answer 5

1) inherent – occurs without previous exposure to the drug
2) acquired – caused by prior exposure to the antibacterial

Question 6

What are the three types of General Adverse Reactions to Antibacterial Drug?

Answer 6

• Allergy or hypersensitivity
• Superinfection
• Organ toxicity

Question 7

What are the Antibiotic Combinations?

Answer 7

• Additive Effect
• Potentiative Effect
• Antagonistic Effect

Question 8

Antibiotic Affecting Protein Synthesis

Answer 8

1. Tetracyclines
2. Macrolides
3. Aminoglycosides

Question 9

Urinary tract Infections

Answer 9

1. SULFONAMIDES
2. TRIMETHOPRIM
3. FLUOROQUINOLONES
4. ANTISEPTICS

Question 10

MYCOBACTERIAL,
FUNGAL AND PARASITIC AGENTS

Answer 10

1. ANTIMYCOBACTERIAL
2. ANTIPROTOZOAL
3. ANTIFUNGAL