Cardiovascular Drugs Flashcards
What are the two primary functions of the Circulatory System?
(1) delivery of oxygen, nutrients, hormones, electrolytes, and other essentials to cells
(2) removal of carbon dioxide and metabolic wastes from cells. In addition, the system helps fight infection.
It is a pump that moves blood through the
arterial tree.
Heart
Defined as a persistent systolic pressure of greater than 140mmHg and/or a diastolic pressure of greater than 90mmHg.
Hypertension
It is the amount of blood ejected from the left ventricle and measured in Lpm.
Cardiac Output
It reduces the cardiovascular and renal morbidity and mortality.
Antihypertensive Therapy
Drugs that accelerate the rate of urine formation
that results to the removal of sodium and water from the body.
Diuretics
This is the drug of choice for preventing kidney damage during acute kidney injury and reduction of intracranial pressure and cerebral edema.
Mannitol
They work on the collecting ducts and DCT by blocking the aldosterone receptor.
Spironolactone, Triamterene, Amiloride
They work in the DCT by inhibiting Na, K,
and Cl resulting to osmotic water loss; can
cause direct relaxation of arterioles which
decreased afterload
Chlorothiazide and Hydrochlorothiazide, Metolazone
It acts on the brain by decreasing NE production
Central Acting Adrenergic Drug
It is used for prevention of migraine headaches and severe dysmenorrhea, mgt of opioid, nicotine and alcohol withdrawal
Clonidine
Drug that restores hair growth.
Minoxidil
It is an early stage of progressive artery disease characterized by pain increasing in severity and frequency and may even occur at rest.
Unstable Angina
This type of Angina is intense but subsides within 15 mins of rest or medication and caused mainly by atherosclerosis and can be triggered by exertion or stress (cold, emotions) and exacerbated by smoking, alcohol, coffee and some drugs.
Chronic Stable Angina
Pathologic state in which the heart is unable to pump in sufficient amounts from the ventricles to meet metabolic needs.
Beta-Blockers