Antibiotic Drugs Flashcards
Also known as prokaryotes which are
single-celled organisms that lack a true
nucleus and nuclear membrane.
Bacteria
Substances that inhibit bacterial growth or kill
bacteria and other microorganisms.
Antibacterial Drugs
We use antiseptics for
Nonliving objects
What are the Five Mechanisms of Antibacterial Action?
1) inhibition of bacterial cell-wall synthesis;
2) alteration of membrane permeability;
3) inhibition of protein synthesis;
4) inhibition of the synthesis of bacterial RNA and DNA;
5) interference with metabolism within the cell
This drug penetrates the bacterial cell wall and have an affinity for the bacteria’s binding sites
Antibacterial Drugs
When bacteria is sensitive to the drug, the pathogen can be
destroyed
Identify the two types of resistance
1) inherent – occurs without previous exposure to the drug;
2) acquired – caused by prior exposure to the antibacterial
It is primarily effective against one type of organism (selective)
Narrow Spectrum
It is effective against gram-positive and gram-negative organisms.
Broad Spectrum
It is a type of therapy where the MO is identified in the lab and the antibiotic therapy is tailored by using the most narrow-spectrum and least toxic drug based on C&S results.
Definitive Therapy
It occurs when the antibiotics reduce or completely eliminate the normal bacterial flora.
Superinfection
Give the 4 host factors
Immune system, Site of infection, Age, Pregnancy
It is for the prevention of infection for clients with GIT, Cardio, Orthopedic or Gynecologic surgeries.
Prophylactic
This is the drug of choice for gram-positive cocci such as Streptococcus pneumoniae, viridans and pyogenes.
Penicillins
What is ‘skin testing’
Skin testing is a bioassay performed on the skin which detects presence of allergenspecific IgE on a patient’s mast cells.
