Cardiovascular Drugs Flashcards
composed of the heart and blood vessels
Circulatory system
controlled by the ANS
Hear rate
determined by 1)
myocardial contractility (force with
which the ventricles contract), 2)
cardiac afterload, 3) cardiac preload
Stroke Volume
amount of tension
(stretch) applied to a muscle before
contraction = force of venous return
Preload
load against which a muscle exerts its force = arterial pressure that the left ventricle overcomes to eject blood
Afterload
Defined as a persistent
systolic pressure of
greater than 140mmHg
and/or a diastolic pressure
of greater than 90mmHg
Hypertension
Determined by the product of
cardiac output and systemic
vascular resistance
Blood pressure
amount of
blood ejected from the left
ventricle and measured in Lpm
CARDIAC OUTPUT
resistance to blood flow
that is determined by the
diameter of the blood vessels and
vascular musculature
SVR
Drugs that accelerate the
rate of urine formation
that results to the
removal of sodium and
water from the body
Diuretics
acts on the
brain by decreasing NE
production
Central acting
at the heart and blood vessels
Peripheral Acting
intense but subsides
within 15 mins of rest or medication and caused mainly by atherosclerosis and can be triggered
by exertion or stress (cold, emotions) and exacerbated by smoking, alcohol, coffee and some drugs.
Chronic Stable Angina
Early stage of progressive artery disease characterized by pain increasing
in severity and frequency and may even occur at
rest
Unstable Angina
from spasms of the smooth muscle that surrounds the coronary arteries and occurs at rest without any triggers but usually occurring at the same time of day
Vasospastic Angina
