Cardiovascular Disorders Flashcards
What are the 3 main risk factors for CAD?
Hyperlipidemia, hypertension, and smoking
What are the 3 characteristics of unstable angina?
- new onset with usual activity
- abrupt increase in severity of stable angina
- angina at rest, hard to control w/ drugs developing 1 month post-MI
How high above the isometric baseline must a ST elevation be to be considered a STEMI?
Greater than 1mm
A total occlusion is most likely to result in what type of infarction?
Transmural; all 3 layers of heart are affected
What is the biggest concern with a right coronary artery block?
Heart block d/t SA and AV node being supplied by this artery in MOST hearts
A block in the left anterior descending artery might affect what part of an ECG?
The QRS complex d/t bundle branches being supplied by this artery
A patient will go into emergency surgery if they have a blockage in which coronary artery?
Left main
How long after the onset of a MI is troponin I & T present? How long does it remain elevated?
3 hrs; 1-2 weeks
How long after the onset of a MI is CK-MB present? How long does it remain elevated?
4-8hrs; peaks within 15-24 hrs
True or false; after 4-6 weeks, necrotic tissue will be functional
False; it will heal into scar tissue which will maintain structural integrity, but will not be functional
What are the two zones that surround the zone of infarction?
Injury and ischemia
Ideally, the time from when a MI patient enters the ER and gets to the cath lab should be what?
Less than 90 minutes
What are the 4 objectives of MI treatment
Reduce preload, after load, contractility, and heart rate
Integrilin, Reopro, and Aggrastat belong to what class of drugs?
Glycoprotein IIb/IIIa Inhibitors (anti-thrombolytics)
True or false; GP IIb/IIIa inhibitors are not to be given to STEMI patients
True; they are only for NSTEMI or unstable angina b/c the platelets have not already aggregated in these conditions
What type of patients are ADP receptor inhibitor drugs for?
Patients who have had mechanical devices inserted, like a stent
How long must a patient be on ADPs if they have a drug-eluding stent?
At least one year
What drug antagonizes the effects of heparin ?
Protamine sulfate
What are the four criteria that must be met to be eligible for fibrinolytic therapy?
<12 from onset of chest pain
chest pain unresponsive to SL nitroglycerin
ST segment elevation on 12 lead EKG
no conditions that predispose to hemorrhage