Cardiovascular A & P Flashcards
What are the functions of blood?
Transports CO2, O2, nutrients, waste products, reservoir of water, heat, hormones.
Maintain blood pressure.
Regulation of PH levels, Thermoregulation, ion composition.
Protection against toxins and pathogens, prevents blood loss via thrombocytes.
Plasma protein maintain osmotic pressure.
What is temperature of blood?
35.6-37.8
What’s the PH level of blood?
7.35-7.45
Calculation of blood volume.
Males- 70 mls per Kg of blood
Females- 60mls per Kg of blood
Children- 80mls per Kg of blood
Newborn 100mls per Kg of blood
What does Hemopoiesis?
The formation of blood which takes place in red bone marrow.
Describe Blood Composition?
Plasma 55% main constituent of plasma is water 90-92% and 7% of plasma protein they are to big to escape via capillaries.
White blood cells and platelets <1%
Red blood cells 45%
Describe composition of plasma protein?
Albumin carriers your drugs, steroid hormones and free fatty acids main function to maintain osmotic pressure.
Globulins three main function are antibodies, they have complex proteins produced by lymphocytes they then bind and neutralise foreign material.
Electrolytes Cary Ca2, K, Na allow nerve impulses.
Nutrients amino acids, carbs as glucose and vitamins for absorption.
Waste production.
Gases, 02,C02
Describe composition of RBC
Bi concave creates larger surface area also allows it to pass through narrow capillaries.
A mature red blood cell has no nucleus so it has more room for haemoglobin.
Life span around 120days then destroyed in spleen.
Describe the clotting process.
Platelets exposed to tissue damage.
Becomes sticky & clump together (release substances that help promote clotting), Prothrombinase.
Prothrombin (plasma protein) and thrombin (enzyme).
Fibrinogen (soluble plasma protein) and fibrin (insoluble protein) clot is formed.
Describe the clotting process.
The damage platelets release thrombokinase.
Thrombokinase & prothrombokinase combine with calcium salts to form thrombin.
Thrombin combines with fibrinogen turns into fibrin.
Fibrin the threads entrapping formed elements creating a clot.
Takes 20 seconds depending on the area and depth.
The two type of Leukocytes (WBC)
Granular visible in the cell.
Agranular less visible in the cell.
What are the Function of the WBC?
To defend the immune system.
WBC can fit out of the blood stream.
Ameboid movement actively move by extending cellular process, allowing the WBC to move towards the infected area.
Neutrophils, eosinophils and monocytes are capable of phagocytes this engulf the FOB.
What are the three types of Granulocytes?
Neutrophils
Eosinophils
Basophils
What are Neutrophils?
50-70% circulating WBC. Usually first at site of injury, attack engulf and digest bacteria that have been marked with Antibodies.
What are Eosinophils?
Engulf bacteria & also secret toxic compounds 2-4% of circulating WBC’s.
What is a Basophils?
<1% of circulating WBC’s involved in the inflammatory response to injury migrate to interstitial fluids outside if blood stream.
Discharged histamine and heparin into tissues, enhanced inflammatory response by mast cells already present in tissue.
What is a Agranulocytes?
2-8% of circulating WBCs, circulation through bloodstream before entering tissues as a tissue macrophage, engulf large items.
Sent out signals to attach other WBCs to the area scar tissue formation role.
What are the 3 types of Lymphocytes?
T cells, cell mediated immunity, enter peripheral tissues and attack foreign cells also coordinate other lymphocytes.
B cells produce and distribute antibodies which attach foreign antigens throughout the body.
Natural Killer (NK) cells detect and destiny abnormal tissue cells (cancer).
Describe the three layers of all Blood Vessels.
Tunica Adventitia-outer layer of fibrous tissue protect & support the vessel. Tunica Media-middle layer containing variable amounts of amounts smooth muscles & elastic tissue. Tunica intima (endothelium) a smooth lining larger only one cell thick,the endothelium only layer present in capillaries.
Describe capillary gas exchange.
Internal respiration is the exchange of gases from the capillary blood & local cells.
External respiration is the exchange of gases between lungs and capillary walls.
O2 comes from the lungs binds with O2 makes haemoglobin, it arrives at the capillaries with their semi permeable walls.
It then diffuse down the concentrations O2 levels are Lowe because of oxygen consumption.