Cardiovascular Flashcards
Dilated Cardiomyopathy
cause
idiopathic; viral myocarditis; alcohol toxicity; post-partum, genetics
Dilated Cardiomyopathy
s/s
left congestive heart failure, dyspnea; S3 gallop, pulmonary rales, increased JVD
Dilated Cardiomyopathy
dx
echocardiogram (left ventricular dilation and dysfunction, large ventricular chamber, decreased ejection fraction); CXR (cardiomegaly, pulmonary congestion); EKG (nonspecific ST/T wave changes); nuclear studies, cardiac cath
Dilated Cardiomyopathy
tx
ACE, diuretics, BB, cardiac transplant, digoxin; alcohol cessation
Hypertrophic Cardiomyopathy cause
genetics (asian), elderly, young athletes
Hypertrophic Cardiomyopathy s/s
dyspnea, angina; syncope, arrhythmias; sudden cardiac death; sustained PMI, loud S4 gallop, variable systolic murmur, bisferiens carotid pulse, jugular venous pulsations
Hypertrophic Cardiomyopathy dx
echocardiogram (LVH, asymmetric septal hypertrophy, small left ventricle, diastolic dysfunction); EKG (nonspecific ST/T wave changes, exaggerated septal Q waves, LVH)
Hypertrophic Cardiomyopathy tx
BB, CBB; disopyramide; surgical ablation of septum, dual-chamber pacing
Restrictive Cardiomyopathy cause
fibrosis or infiltration of ventricular wall because of collage-defect diseases (amyloidosis, radiation, post-op changes, DM, fibrosis)
Restrictive Cardiomyopathy s/s
decreased exercise tolerance; right sided congestive heart failure; pulmonary HTN
Restrictive Cardiomyopathy dx
echocardiogram (diagnostic); CXR (enlarged cardiac silhouette); EKG changes; Cardiac MRI; cardiac cath (reduced LV function); endomyocardial biopsy (r/o other cardiomyopathies and pericarditis)
Restrictive Cardiomyopathy tx
diuretics
Takotsubo Cardiomyopathy (broken heart syndrome) cause
stress-induced; major catecholamine discharge
Takotsubo Cardiomyopathy (broken heart syndrome) s/s
indistinguishable from acute MI
Takotsubo Cardiomyopathy (broken heart syndrome) dx
EKG changes, mild cardiac enzyme elevation suggestive of MI; cardiac cath (hypocontractility of left ventricular apex, patent coronary arteries)
Takotsubo Cardiomyopathy (broken heart syndrome) tx
supportive; avoid inotropes
Atrial Fibrillation cause
age; excessive alcohol use/withdrawal; structural abnormality
Atrial Fibrillation s/s
palpitations, angina, fatigue, heart failure symptoms; irregularly irregular
Atrial Fibrillation dx
EKG (narrow-complex irregularly irregular rhythm)
Atrial Fibrillation tx
cardioversion (200 J; adenosine); anticoagulants (heparin, LMWH, warfarin, dabigatran); antiarrhythmics w/ heart failure (digoxin, amiodarone, dronedarone); w/o heart failure (metoprolol, diltiazem/verapamil)
Atrial Flutter cause
COPD, heart failure, atrial septal defect, CAD
Atrial Flutter s/s
palpitations, angina, fatigue, heart failure symptoms
Atrial Flutter dx
○ EKG (saw tooth pattern; no P waves)
Atrial Flutter tx
cardioversion (50 J; ibutilide); anticoagulants (heparin, LMWH, warfarin, dabigatran); antiarrhythmics (amiodarone, procainamide); chronic (metoprolol, diltiazem/verapamil)
Atrioventricular Block cause
refractory conduction of impulses from atria to ventricles through AV node or bundle of HIS
Atrioventricular Block s/s
asymptomatic (1st degree); weakness, fatigue, light-headedness, syncope
Atrioventricular Block dx
EKG
■ 1st degree block: PR interval is >0.21s
■ 2nd degree block type 1 (Wenckebach): progressive lengthening of PR interval, shortening of RR, dropped beat
■ 2nd degree block type 2: normal length PR interval, dropped beat
■ 3rd degree block: complete dissociation between P waves and QRS intervals
Atrioventricular Block tx
no treatment (1st degree); permanent pacing (esp type 2 and 3rd degree)
Bundle Branch Block cause
myocardial infarctions; CAD
Bundle Branch Block dx
EKG
■ RBBB: wide QRS >.12s; RsR in V1/ V2 (“m”)
■ LBBB: wide QRS >.12s; broad slurred R in V5/V6, deep S in V1; ST elevations in V1-V3
Sick Sinus Syndrome cause
digitalis, CCB, BB, sympathologic agents, antiarrhythmic drugs, aerosol propellant abuse; underlying collagen vascular or metastatic disease, surgical injury, coronary disease
Sick Sinus Syndrome s/s
asymptomatic; syncope, dizziness, confusion, heart failure, palpitations, decreased exercise tolerance
Sick Sinus Syndrome dx
EKG (sinus brady, sinus pause, sinus arrest)
Sick Sinus Syndrome tx
permanent pacing
Paroxysmal Supraventricular Tachycardia cause
not structural, Wolff-parkinson white syndrome
Paroxysmal Supraventricular Tachycardia s/s
palpitations, angina, fatigue, heart failure symptoms
Paroxysmal Supraventricular Tachycardia dx
EKG (regular, p wave, narrow-complex tachy)
Paroxysmal Supraventricular Tachycardia tx
valsalva maneuvers; adenosine IV push -> BB/CBB; synchronized cardioversion prn; catheter ablative surgery (recurrent/sustained)
premature beats
PAc, PJC, PVC
PAC’s
benign; no treatment required
PJC
drug toxicity, electrolyte imbalance, mitral valve surgery, cold water immersion
PVC
benign; ischemia, electrolyte disturbance; skipped beats; BB/CBB
Ventricular Tachycardia cause
electrolyte abnormalities; acute MI; dilated cardiomyopathy
Ventricular Tachycardia s/s
palpitations; dizziness, syncope, sudden death; severe hypotension
Ventricular Tachycardia dx
EKG (>100bpm w/ 3 PVCs, nonsustained <30s vs sustained >30s)
Ventricular Tachycardia tx
cardioversion (amiodarone) vs defibrillation/CPR; lidocaine, procainamide; ICD (sustained/recurrent)
Ventricular Fibrillation cause
disorganized electrical impulses, no pumping action of heart
Ventricular Fibrillation s/s
sudden unconsciousness and death
Ventricular Fibrillation dx
EKG (irregular, rapid waveform of varying amplitude)
Ventricular Fibrillation tx
Defibrillation/CPR and cardioversion
Torsades de Pointes cause
spontaneous; hypokalemia, hypomagnesaemia following administration of drugs that prolong QT
Torsades de s/s
polymorphic Vtach; palpitations, dizziness, syncope, sudden death
Torsades de Pointes dx
Vtach w/ QRS twists on baseline
Torsades de Pointes tx
IV magnesium; correct electrolyte abnormalities; isoproterenol infusion; permanent pacemaker
Brugada Syndrome s/s
syncope, ventricular fibrillation, sudden death
Heart Failure cause
myocardial/pericardial disorders; valvular/congenital abnormalities; noncardiac (thyrotoxicosis, severe anemia)
Heart s/s
exertional dyspnea, cough, fatigue, orthopnea, paroxysmal nocturnal dyspnea, bibasilar rales, gallops, exercise intolerance (left-sided, exertional pulmonary congestion); JVD, nontender hepatic congestion, decreased appetite/nausea, pitting edema (right-sided, systemic pulmonary congestion); parasternal lift, enlarged displaced, hyperdynamic apical impulse, diminished S1, S3 gallop, pallor, clammy skin, nocturia, hypotension
Heart Failure dx
echocardiogram (decreased ejection fraction, change in size/function of chambers, valve abnormalities, etc); CXR (cardiomegaly, pulmonary effusions, Kerley B lines, venous dilation); elevated BNP; cardiac cath; anemia, renal insufficiency, hyperkalemia, hyponatremia
Heart Failure tx
exercise, low Na diet, stress reduction, no alcohol/smoking; ACEI/ARBs, loop/HCTZ diuretics; BB, aldosterone receptor agonists; digitalis
Cardiogenic Shock cause
hypovolemic shock (hemorrhage, loss of fluid/electrolytes); cardiogenic shock (MI, dysrhythmias, HF, HTN, contusion, myocarditis); obstructive shock (tension pneumo, tamponade, COPD, PE); septic/neurogenic shock (sepsis/infection, spinal cord injury, ADEs of spinal/epidural anesthesia)
Cardiogenic Shock s/s
hypotension, lack of hypovolemia, poor tissue perfusion; AMS (confusion, obtunded), oliguria, insulin resistance, metabolic acidosis, cool/mottled extremities, diminished cap refill, weak peripheral pulses
Cardiogenic Shock dx
CBC, blood type/cross match, coags, electrolytes, glucose, urinalysis, creatinine (determine cause), ABG, EKG, biomarkers, lactate levels
Cardiogenic Shock tx
airway, breathing, circulation; treat cause of shock; oxygen/fluid bolus; inotropes to increase cardiac output (epi, dobutamine), chronotropes to alter rate (adrenaline, digoxin), pressors to increase vascular tone (dopamine, phenylephrine); PCI
Orthostatic Hypotension cause
reduced cardiac output, paroxysmal cardiac dysrhythmias, low blood volume, medications, endocrine, neurologic, and metabolic disorders
Orthostatic Hypotension s/s
dizziness, worse with movement; headache
Orthostatic Hypotension dx
orthostatic vitals (>20mmHg drop in SBP or >10mmHg drop in DBP between sitting and standing, rise in pulse of >15bpm); CBC, BMP, EKG, tilt test
Orthostatic Hypotension tx
fluids; remove medication causes
Essential Hypertension cause
genetic, increased age, black ethnicity, environmental factors, tobacco, sedentary lifestyle, polycythemia, NSAID use, metabolic syndrome
Essential Hypertension s/s
most asymptomatic or nonspecific headache
Essential Hypertension dx
BP >140/>90 at 2 visits; EKG (LVH and strain); CXR (ventricular hypertrophy); dec H&H, elevated BUN, creatinine, or glucose; urinary glucose, protein, sediment, lipid profile
Essential Hypertension tx
DASH diet; ACE inhibitors, diuretics (loop vs HCTZ), Beta blockers, CCB (amlodipine), aldosterone receptor antagonists (spironolactone), renin inhibitor (aliskiren)
Secondary Hypertension cause
renal disease, renal artery stenosis, coarctation of aorta, pheochromocytoma, cushing syndrome, hyperthyroidism, chronic steroid use, NSAID use
Secondary Hypertension s/s
most asymptomatic; nonspecific headache