Cardiovascular Flashcards
Dilated Cardiomyopathy
cause
idiopathic; viral myocarditis; alcohol toxicity; post-partum, genetics
Dilated Cardiomyopathy
s/s
left congestive heart failure, dyspnea; S3 gallop, pulmonary rales, increased JVD
Dilated Cardiomyopathy
dx
echocardiogram (left ventricular dilation and dysfunction, large ventricular chamber, decreased ejection fraction); CXR (cardiomegaly, pulmonary congestion); EKG (nonspecific ST/T wave changes); nuclear studies, cardiac cath
Dilated Cardiomyopathy
tx
ACE, diuretics, BB, cardiac transplant, digoxin; alcohol cessation
Hypertrophic Cardiomyopathy cause
genetics (asian), elderly, young athletes
Hypertrophic Cardiomyopathy s/s
dyspnea, angina; syncope, arrhythmias; sudden cardiac death; sustained PMI, loud S4 gallop, variable systolic murmur, bisferiens carotid pulse, jugular venous pulsations
Hypertrophic Cardiomyopathy dx
echocardiogram (LVH, asymmetric septal hypertrophy, small left ventricle, diastolic dysfunction); EKG (nonspecific ST/T wave changes, exaggerated septal Q waves, LVH)
Hypertrophic Cardiomyopathy tx
BB, CBB; disopyramide; surgical ablation of septum, dual-chamber pacing
Restrictive Cardiomyopathy cause
fibrosis or infiltration of ventricular wall because of collage-defect diseases (amyloidosis, radiation, post-op changes, DM, fibrosis)
Restrictive Cardiomyopathy s/s
decreased exercise tolerance; right sided congestive heart failure; pulmonary HTN
Restrictive Cardiomyopathy dx
echocardiogram (diagnostic); CXR (enlarged cardiac silhouette); EKG changes; Cardiac MRI; cardiac cath (reduced LV function); endomyocardial biopsy (r/o other cardiomyopathies and pericarditis)
Restrictive Cardiomyopathy tx
diuretics
Takotsubo Cardiomyopathy (broken heart syndrome) cause
stress-induced; major catecholamine discharge
Takotsubo Cardiomyopathy (broken heart syndrome) s/s
indistinguishable from acute MI
Takotsubo Cardiomyopathy (broken heart syndrome) dx
EKG changes, mild cardiac enzyme elevation suggestive of MI; cardiac cath (hypocontractility of left ventricular apex, patent coronary arteries)
Takotsubo Cardiomyopathy (broken heart syndrome) tx
supportive; avoid inotropes
Atrial Fibrillation cause
age; excessive alcohol use/withdrawal; structural abnormality
Atrial Fibrillation s/s
palpitations, angina, fatigue, heart failure symptoms; irregularly irregular
Atrial Fibrillation dx
EKG (narrow-complex irregularly irregular rhythm)
Atrial Fibrillation tx
cardioversion (200 J; adenosine); anticoagulants (heparin, LMWH, warfarin, dabigatran); antiarrhythmics w/ heart failure (digoxin, amiodarone, dronedarone); w/o heart failure (metoprolol, diltiazem/verapamil)
Atrial Flutter cause
COPD, heart failure, atrial septal defect, CAD
Atrial Flutter s/s
palpitations, angina, fatigue, heart failure symptoms
Atrial Flutter dx
○ EKG (saw tooth pattern; no P waves)
Atrial Flutter tx
cardioversion (50 J; ibutilide); anticoagulants (heparin, LMWH, warfarin, dabigatran); antiarrhythmics (amiodarone, procainamide); chronic (metoprolol, diltiazem/verapamil)
Atrioventricular Block cause
refractory conduction of impulses from atria to ventricles through AV node or bundle of HIS
Atrioventricular Block s/s
asymptomatic (1st degree); weakness, fatigue, light-headedness, syncope
Atrioventricular Block dx
EKG
■ 1st degree block: PR interval is >0.21s
■ 2nd degree block type 1 (Wenckebach): progressive lengthening of PR interval, shortening of RR, dropped beat
■ 2nd degree block type 2: normal length PR interval, dropped beat
■ 3rd degree block: complete dissociation between P waves and QRS intervals
Atrioventricular Block tx
no treatment (1st degree); permanent pacing (esp type 2 and 3rd degree)
Bundle Branch Block cause
myocardial infarctions; CAD
Bundle Branch Block dx
EKG
■ RBBB: wide QRS >.12s; RsR in V1/ V2 (“m”)
■ LBBB: wide QRS >.12s; broad slurred R in V5/V6, deep S in V1; ST elevations in V1-V3
Sick Sinus Syndrome cause
digitalis, CCB, BB, sympathologic agents, antiarrhythmic drugs, aerosol propellant abuse; underlying collagen vascular or metastatic disease, surgical injury, coronary disease
Sick Sinus Syndrome s/s
asymptomatic; syncope, dizziness, confusion, heart failure, palpitations, decreased exercise tolerance
Sick Sinus Syndrome dx
EKG (sinus brady, sinus pause, sinus arrest)
Sick Sinus Syndrome tx
permanent pacing
Paroxysmal Supraventricular Tachycardia cause
not structural, Wolff-parkinson white syndrome
Paroxysmal Supraventricular Tachycardia s/s
palpitations, angina, fatigue, heart failure symptoms
Paroxysmal Supraventricular Tachycardia dx
EKG (regular, p wave, narrow-complex tachy)
Paroxysmal Supraventricular Tachycardia tx
valsalva maneuvers; adenosine IV push -> BB/CBB; synchronized cardioversion prn; catheter ablative surgery (recurrent/sustained)
premature beats
PAc, PJC, PVC
PAC’s
benign; no treatment required
PJC
drug toxicity, electrolyte imbalance, mitral valve surgery, cold water immersion
PVC
benign; ischemia, electrolyte disturbance; skipped beats; BB/CBB
Ventricular Tachycardia cause
electrolyte abnormalities; acute MI; dilated cardiomyopathy
Ventricular Tachycardia s/s
palpitations; dizziness, syncope, sudden death; severe hypotension
Ventricular Tachycardia dx
EKG (>100bpm w/ 3 PVCs, nonsustained <30s vs sustained >30s)
Ventricular Tachycardia tx
cardioversion (amiodarone) vs defibrillation/CPR; lidocaine, procainamide; ICD (sustained/recurrent)
Ventricular Fibrillation cause
disorganized electrical impulses, no pumping action of heart
Ventricular Fibrillation s/s
sudden unconsciousness and death
Ventricular Fibrillation dx
EKG (irregular, rapid waveform of varying amplitude)
Ventricular Fibrillation tx
Defibrillation/CPR and cardioversion
Torsades de Pointes cause
spontaneous; hypokalemia, hypomagnesaemia following administration of drugs that prolong QT
Torsades de s/s
polymorphic Vtach; palpitations, dizziness, syncope, sudden death
Torsades de Pointes dx
Vtach w/ QRS twists on baseline
Torsades de Pointes tx
IV magnesium; correct electrolyte abnormalities; isoproterenol infusion; permanent pacemaker
Brugada Syndrome s/s
syncope, ventricular fibrillation, sudden death
Heart Failure cause
myocardial/pericardial disorders; valvular/congenital abnormalities; noncardiac (thyrotoxicosis, severe anemia)
Heart s/s
exertional dyspnea, cough, fatigue, orthopnea, paroxysmal nocturnal dyspnea, bibasilar rales, gallops, exercise intolerance (left-sided, exertional pulmonary congestion); JVD, nontender hepatic congestion, decreased appetite/nausea, pitting edema (right-sided, systemic pulmonary congestion); parasternal lift, enlarged displaced, hyperdynamic apical impulse, diminished S1, S3 gallop, pallor, clammy skin, nocturia, hypotension
Heart Failure dx
echocardiogram (decreased ejection fraction, change in size/function of chambers, valve abnormalities, etc); CXR (cardiomegaly, pulmonary effusions, Kerley B lines, venous dilation); elevated BNP; cardiac cath; anemia, renal insufficiency, hyperkalemia, hyponatremia
Heart Failure tx
exercise, low Na diet, stress reduction, no alcohol/smoking; ACEI/ARBs, loop/HCTZ diuretics; BB, aldosterone receptor agonists; digitalis
Cardiogenic Shock cause
hypovolemic shock (hemorrhage, loss of fluid/electrolytes); cardiogenic shock (MI, dysrhythmias, HF, HTN, contusion, myocarditis); obstructive shock (tension pneumo, tamponade, COPD, PE); septic/neurogenic shock (sepsis/infection, spinal cord injury, ADEs of spinal/epidural anesthesia)
Cardiogenic Shock s/s
hypotension, lack of hypovolemia, poor tissue perfusion; AMS (confusion, obtunded), oliguria, insulin resistance, metabolic acidosis, cool/mottled extremities, diminished cap refill, weak peripheral pulses
Cardiogenic Shock dx
CBC, blood type/cross match, coags, electrolytes, glucose, urinalysis, creatinine (determine cause), ABG, EKG, biomarkers, lactate levels
Cardiogenic Shock tx
airway, breathing, circulation; treat cause of shock; oxygen/fluid bolus; inotropes to increase cardiac output (epi, dobutamine), chronotropes to alter rate (adrenaline, digoxin), pressors to increase vascular tone (dopamine, phenylephrine); PCI
Orthostatic Hypotension cause
reduced cardiac output, paroxysmal cardiac dysrhythmias, low blood volume, medications, endocrine, neurologic, and metabolic disorders
Orthostatic Hypotension s/s
dizziness, worse with movement; headache
Orthostatic Hypotension dx
orthostatic vitals (>20mmHg drop in SBP or >10mmHg drop in DBP between sitting and standing, rise in pulse of >15bpm); CBC, BMP, EKG, tilt test
Orthostatic Hypotension tx
fluids; remove medication causes
Essential Hypertension cause
genetic, increased age, black ethnicity, environmental factors, tobacco, sedentary lifestyle, polycythemia, NSAID use, metabolic syndrome
Essential Hypertension s/s
most asymptomatic or nonspecific headache
Essential Hypertension dx
BP >140/>90 at 2 visits; EKG (LVH and strain); CXR (ventricular hypertrophy); dec H&H, elevated BUN, creatinine, or glucose; urinary glucose, protein, sediment, lipid profile
Essential Hypertension tx
DASH diet; ACE inhibitors, diuretics (loop vs HCTZ), Beta blockers, CCB (amlodipine), aldosterone receptor antagonists (spironolactone), renin inhibitor (aliskiren)
Secondary Hypertension cause
renal disease, renal artery stenosis, coarctation of aorta, pheochromocytoma, cushing syndrome, hyperthyroidism, chronic steroid use, NSAID use
Secondary Hypertension s/s
most asymptomatic; nonspecific headache
Secondary Hypertension dx
BP >140/>90 at 2 visit; EKG (LVH and strain); CXR (ventricular hypertrophy); dec H&H, elevated BUN, creatinine, or glucose; urinary glucose, protein, sediment, lipid profile; determine underlying disease process
Secondary Hypertension tx
DASH diet; ACE inhibitors, diuretics (loop vs HCTZ), Beta blockers, CCB (amlodipine), aldosterone receptor antagonists (spironolactone), renin inhibitor (aliskiren)
Hypertensive Emergencies cause
uncontrolled hypertension
Hypertensive Emergencies s/s
papilledema, encephalopathy, nephropathy, ICH, aortic dissection, preeclampsia/eclampsia, pulmonary edema, unstable angina, MI
Hypertensive Emergencies dx
SBP >130 with end organ damage; CT, MRI, echo, renal vessel imaging
Hypertensive Emergencies tx
sodium nitroprusside; labetalol, fenoldopam, nicardipine; NTG; slowly lower BP to prevent stroke 25% in MAP w/in 1st hour
Acute Myocardial Infarction: STEMI cause
acute coronary thrombosis; CAD, Afib, etc
Acute Myocardial Infarction: STEMI s/s
chest pain (pressure) radiating to neck, arm, back; lasts longer than angina; diaphoresis, N/V
Acute Myocardial Infarction: STEMI dx
EKG (ST elevation, reciprocal ST depression, inverted T waves)
Acute Myocardial Infarction: STEMI tx
aspirin, morphine, NTG; oxygen; cardiac cath; heparin/tpa prn
Acute Myocardial Infarction: NSTEMI cause
acute coronary thrombosis
Acute Myocardial Infarction: NSTEMI s/s
chest pain (pressure) radiating to neck, arm, back; lasts longer than angina; diaphoresis, N/V; asymptomatic
Acute Myocardial Infarction: NSTEMI dx
EKG (nonspecific ST changes, NO ST elevation); elevated cardiac enzymes
Acute Myocardial Infarction: NSTEM tx
aspirin, morphine, oxygen, NTG; cardiac stents
Stable Angina Pectoris cause
CAD, DM, hyperlipidemia, smoking, HTN, males
Stable Angina Pectoris s/s
chest pain, may radiate, lasts <30min; relieved with NTG or rest; dyspnea, nausea, diaphoresis, numbness, fatigue
Stable Angina Pectoris dx
coronary angiogram (definitive); EKG (ST depression w/ exertion, T wave inversion, poor R wave progression); Non-invasive stress test
Stable Angina Pectoris tx
BB, ASA; NTG prn; angioplasty, CABG
Unstable Angina Pectoris cause
CAD, DM, hyperlipidemia, smoking, HTN, males
Unstable Angina Pectoris s/s
severe and worsening from prior; chest pain, may radiate, lasts >30min; relieved with NTG or rest; dyspnea, nausea, diaphoresis, numbness, fatigue
Unstable Angina Pectoris dx
coronary angiogram (definitive); non elevated cardiac enzymes; EKG (ST depression w/ exertion, T wave inversion, poor R wave progression); Non-invasive stress test
Unstable Angina Pectoris tx
NTG, ASA, BB; (LMWH, clopidogrel); oxygen, fluids; cardiac cath
Prinzmetal Variant Angina cause
CAD, DM, hyperlipidemia, smoking, HTN, males
Prinzmetal Variant Angina s/s
occurs in morning, at rest; chest pain; not due to exertion; ventricular dysrhythmias
Prinzmetal Variant Angina dx
EKG (transient ST elevation); Non-invasive stress test; cardiac angiogram
Prinzmetal Variant Angina tx
CCB, NTG
Aortic Aneurysm/Dissection cause
weakness in vessel wall, atherosclerosis, congenital defects due to syphilis, trauma, vasculitis, Marfan syndrome
Aortic Aneurysm/Dissection s/s
asymptomatic; pulsatile abdominal mass; abdominal/back pain radiating to leg or testis, dyspnea, “ripping”/”tearing” chest pain radiating to back, hypotension, shock; BP difference of >20mmHg between upper and lower extremities
Aortic Aneurysm/Dissection dx
abdominal US (abdominal), CT w/ IV contrast (identifies rupture) CT/MRI (thoracic); CXR (widened mediastinum, displaced aortic notch); CBC, BMP, coag studies
Aortic Aneurysm/Dissection tx
endovascular/open surgical repair; manage BP w/ labetalol, nitroprusside [goal BP <150]; symptomatic will likely rupture, ruptured are fatal
Arterial Embolism/Thrombosis cause
hx of Afib; injury to vessel wall, increased clotting, atherosclerosis
Arterial Embolism/Thrombosis s/s
decreased pulses, cold extremities, lack of movement, muscle pain, numbness in fingers and hands
Arterial Embolism/Thrombosis dx
angiography; duplex ultrasound; PT, CBC
Arterial Embolism/Thrombosis tx
anticoagulant/antiplatelet; thrombolytics; pain meds
Giant Cell Arteritis (Temporal arteritis) cause
affects superficial temporal arteries; unknown cause (genetic, environmental, autoimmune)
Giant Cell Arteritis (Temporal arteritis) s/s
abrupt or insidious onset; unilateral headache, jaw claudication, fever, fatigue, malaise; neck/torso/shoulder/pelvic girdle pain
Giant Cell Arteritis (Temporal arteritis) dx
biopsy; elevated ESR/CRP; angiography, ultrasound, MRI/MRA
Giant Cell Arteritis (Temporal arteritis) tx
glucocorticoid therapy (prednisone)
Peripheral Arterial Disease cause
atherosclerosis; trauma, hypovolemia, inflammatory arteritis, polycythemia, dehydration, hypercoaguable states
Peripheral Arterial Disease s/s
intermittent claudication, foot/lower leg pain w/ exercise relieved by rest; weak/absent femoral/distal pulses; aortic/iliac/femoral bruits; loss of hair, shiny atrophic skin, and pallor with dependent rubor to skin; numbness, tingling, ischemic ulcerations
Peripheral Arterial Disease dx
angiography; doppler ultrasound; ankle-brachial index
Peripheral Arterial Disease tx
control underlying diseases (tobacco use, DM, HTN, hyperlipidemia); BB, ACEI, statins, exercise; antiplatelet therapy; revascularization
Phlebitis/Thrombophlebitis cause
virchow triad (stasis, vascular injury, hypercoagulability); spontaneous, following trauma, PICC line; hormone replacement, bed rest; clotting problems (factor 5 leiden, protein C, protein S); cancer
Phlebitis/Thrombophlebitis s/s
dull pain, erythema, tenderness, induration of involved vein (MC saphenous v); swelling, warmth, erythema to lower extremity
Phlebitis/Thrombophlebitis dx
duplex ultrasound; Wells score; venography; d-dimer; CT angiography (chest)
Phlebitis/Thrombophlebitis tx
LMWH (enoxaparin), then warfarin; bed rest, heat to area, elevation, NSAIDs; antibiotics w/ infection; frequent ambulation, compression devices
Varicose Veins cause
pregnancy, obesity, family history, prolonged sitting; incompetent valves
Varicose Veins s/s
Dilated, tortuous superficial veins; smaller blue-green, flat reticular veins, telangiectasias, spider veins; aching with fatigue; chronic distal edema, abnormal pigmentation, fibrosis, atrophy, skin ulceration
Varicose Veins dx
doppler sonography
Varicose Veins tx
elastic stockings, leg elevation, regular exercise; Laser ablation, endovenous radiofrequency, compression sclerotherapy
Venous Insufficiency cause
incompetent valves; thick, scarred veins, dilated veins
Venous Insufficiency s/s
pruritus, swelling of legs and ankles, eczema, pitting edema, fibrosis of skin, skin hyperpigmentation, stasis dermatitis, dull ache
Venous Insufficiency dx
duplex ultrasound
Venous Insufficiency tx
compression stocking, avoid long sitting/standing, elevate leg, reduce edema, pneumatic compression
Venous Thrombosis cause
stasis, vascular injury, hypercoagulability; OC, obesity, long-distance travel, lupus
Venous Thrombosis s/s
dull pain, erythema, swelling, tenderness, induration of vein
Venous Thrombosis dx
duplex US, venography, d-dimer and CT (pulmonary)
Venous Thrombosis tx
bed rest, heat, elevation, NSAIDs, anticoagulation with LMWH or UFH and warfarin
Aortic Stenosis cause
bicuspid AV, congenital, rheumatic heart disease, connective tissue disorders, infection, senile degeneration
Aortic Stenosis s/s
dyspnea, fatigue, decreased exercise tolerance, cough, rales, paroxysmal nocturnal dyspnea, hemoptysis, hoarseness; thready pulses; harsh midsystolic murmur in 2nd RICS, radiates to LSB and neck, with thrill
Aortic Stenosis dx
transesophageal echocardiogram and cardiac cath (definitive); CXR (left sided atrial enlargement, ventricular hypertrophy)
Aortic Stenosis tx
surgical repair/replacement of valve (PCI, balloon valvuloplasty); diuretics, vasodilators (pulmonary congestion); digoxin, BB (dysrhythmias)
Aortic Regurgitation cause
bicuspid AV, congenital, rheumatic heart disease, connective tissue disorders, infection, senile degeneration
Aortic Regurgitation s/s
dyspnea, fatigue, decreased exercise tolerance, cough, rales, paroxysmal nocturnal dyspnea, hemoptysis, hoarseness; bounding pulses, widened pulse pressure; soft systolic and diastolic decrescendo “blowing” murmur in 2nd/4th LICS radiating to RSB and apex
Aortic Regurgitation dx
transesophageal echocardiogram and cardiac cath (definitive); CXR (left sided atrial enlargement, ventricular hypertrophy)
Aortic Regurgitation tx
surgical repair/replacement of valve (PCI, balloon valvuloplasty); diuretics, vasodilators (pulmonary congestion); digoxin, BB (dysrhythmias)
Mitral Stenosis cause
bicuspid AV, congenital, rheumatic heart disease, connective tissue disorders, infection, senile degeneration
Mitral Stenosis s/s
dyspnea, fatigue, decreased exercise tolerance, cough, rales, paroxysmal nocturnal dyspnea, hemoptysis, hoarseness; mid-diastolic murmur in apex, snap follows S2
Mitral Stenosis dx
transesophageal echocardiogram and cardiac cath (definitive); CXR (atrial enlargement)
Mitral Stenosis tx
surgical repair/replacement of valve (PCI, balloon valvuloplasty); diuretics, vasodilators (pulmonary congestion); digoxin, BB (dysrhythmias)
Mitral Regurgitation cause
bicuspid AV, congenital, rheumatic heart disease, connective tissue disorders, infection, senile degeneration
Mitral Regurgitation s/s
dyspnea, fatigue, decreased exercise tolerance, cough, rales, paroxysmal nocturnal dyspnea, hemoptysis, hoarseness; pansystolic blowing murmur in apex, radiates to left axilla
Mitral Regurgitation dx
transesophageal echocardiogram and cardiac cath (definitive); CXR (atrial enlargement)
Mitral Regurgitation tx
surgical repair/replacement of valve (PCI, balloon valvuloplasty); diuretics, vasodilators (pulmonary congestion); digoxin, BB (dysrhythmias)
Mitral Valve Prolapse cause
congenital, thin females w/ minor chest wall deformities
Mitral Valve Prolapse s/s
asymptomatic; midsystolic clicks, late systolic murmur
Mitral Valve Prolapse dx
transesophageal echocardiogram and cardiac cath (definitive); CXR (atrial enlargement)
Mitral Valve Prolapse tx
surgical repair/replacement of valve (PCI, balloon valvuloplasty); diuretics, vasodilators (pulmonary congestion); digoxin, BB (dysrhythmias)
Tricuspid Stenosis cause
congenital (during infancy/childhood); rheumatic scarring, connective tissue disease, endocarditis (adults)
Tricuspid Stenosis s/s
exercise intolerance, JVD, peripheral edema, hepatomegaly; diastolic murmur
Tricuspid Stenosis dx
echocardiogram and cardiac cath (definitive); CXR (prominent right heart border w/ dilation of SVC); EKG (RAD, right atrial enlargement, RVH)
Tricuspid Stenosis tx
surgical repair/replacement; sodium restriction, diuretics; vasodilators, positive inotropic agents (pulmonary HTN)
Tricuspid Regurgitation cause
congenital (during infancy/childhood); rheumatic scarring, connective tissue disease, endocarditis (adults); intrinsic or functional
Tricuspid Regurgitation s/s
exercise intolerance, JVD, peripheral edema, hepatomegaly; holosystolic murmur at LLSB, radiates to right sternum and xiphoid
Tricuspid Regurgitation dx
echocardiogram and cardiac cath (definitive); CXR (prominent right heart border w/ dilation of SVC); EKG (RAD, right atrial enlargement, RVH)
Tricuspid Regurgitation tx
surgical repair/replacement; sodium restriction, diuretics; vasodilators, positive inotropic agents (pulmonary HTN)
Pulmonary Stenosis cause
congenital (during infancy/childhood); rheumatic scarring, connective tissue disease, endocarditis (adults)
Pulmonary Stenosis s/s
exercise intolerance, JVD, peripheral edema, hepatomegaly; midsystolic crescendo-decrescendo murmur in 2nd/3rd LICS, radiates to left shoulder/neck
Pulmonary Stenosis dx
echocardiogram and cardiac cath (definitive); CXR (prominent right heart border w/ dilation of SVC); EKG (RAD, right atrial enlargement, RVH)
Pulmonary Stenosis tx
surgical repair/replacement; sodium restriction, diuretics; vasodilators, positive inotropic agents (pulmonary HTN)
Pulmonary Regurgitation cause
congenital (during infancy/childhood); rheumatic scarring, connective tissue disease, endocarditis (adults)
Pulmonary Regurgitation s/s
exercise intolerance, JVD, peripheral edema, hepatomegaly; diastolic murmur
Pulmonary Regurgitation dx
echocardiogram and cardiac cath (definitive); CXR (prominent right heart border w/ dilation of SVC); EKG (RAD, right atrial enlargement, RVH)
Pulmonary Regurgitation tx
surgical repair/replacement; sodium restriction, diuretics; vasodilators, positive inotropic agents (pulmonary HTN)
Bacterial Endocarditis cause
staph aureus (acute); strep viridans (subacute); staph epidermidis (prosthetic)
Bacterial Endocarditis s/s
fever, cough, dyspnea, pallor, splenomegaly; palatal/conjunctival/subungual petechiae, splinter hemorrhages, osler nodes (painful), janeway lesions (not painful)
Bacterial Endocarditis dx
echocardiogram; blood cultures q1hr x3; Duke Criteria
Bacterial Endocarditis tx
gentamicin, cephalosporin, vancomycin (empirical); nafcillin, gentamicin (acute); PCN, gentamicin (subacute)
Acute Pericarditis cause
idiopathic; viral/bacterial infection; autoimmune (RA, SLE); radiation therapy, myxedema, TB, post-MI (dressler syndrome)
Acute Pericarditis s/s
sharp, pleuritic substernal chest pain, radiates to back/neck/shoulders; relieved by sitting upright and leaning forward, worse with inspiration; cardiac friction rub, JVD, cardiac tamponade (hypotension, tachycardia)
Acute Pericarditis dx
elevated WBC; EKG (diffuse ST elevation, T wave inversions, PR depression); CT/MRI
Acute Pericarditis tx
steroids (prednisone), NSAIDs/ASA; pericardiectomy, antibiotics, IV hydration
Cardiac Tamponade cause
fluid compromises cardiac filling and impairs cardiac output; MI, PE, trauma
Cardiac Tamponade s/s
tachycardia, tachypnea, narrow pulse pressure, JVD, pulsus paradoxus; becks triad (low BP, JVD, muffled heart sounds)
Cardiac Tamponade dx
CXR, echo, EKG, clinical (becks triad + pulsus paradoxus)
Cardiac Tamponade tx
pericardiocentesis (hemodynamic compromise), steroids/NSAIDs (inflammation), pericardiectomy
Pericardial Effusion cause
pericarditis, uremia, cardiac trauma
Pericardial Effusion s/s
painless; chest pain, cough, dyspnea
Pericardial Effusion dx
CXR (fluid around heart); echocardiogram; EKG (nonspecific T changes, low QRS, electrical alternans)
Pericardial Effusion tx
pericardiocentesis (hemodynamic compromise), steroids/NSAIDs (inflammation), pericardiectomy