Cardiovascular Flashcards
Patients with ________ and _______ are treated to the same values of hypertension
Diabetes
Hypertension
Patients > 60 y/o are treated when systolic pressure over _____ or diastolic over _____ unless they have diabetes or CKD
150
90
Stage 1 hypertension
Systolic 140-159
Diastolic 90-100
Stage 2 hypertension
Systolic > 160
Diastolic > 100
Who should undergo evaluation for secondary hypertension?
- Severe or resistant hypertension (not responsive to at least 3 medications, one of which must include a diuretic)
- Age < 30 who are otherwise healthy
- Malignant or very rapidly occurring HTN
Abdominal bruit with hypertension
Renal artery stenosis
Hypokalemia and hypernatremia. Increased aldosterone:renin ratio and plasma aldosterone over 15 with hypertension
Hyperaldosteronism
Hypertension with elevated creatinine
Primary kidney disease
Acute episodes of hypertension with headache, palpitations and sweating
Pheochromocytoma
Hypertension in a child. BP high in upper extremities vs lower extremities with diminished femoral pulses
Coarctation of the aorta
Routine labs ordered with hypertension (6)
- UA
- Urine micro albumin
- EKG
- CBC
- BMP
- Lipid panel
First step treatment for hypertension
Initiate lifestyle recommendations such as weight loss, DASH diet, smoking cessation, moderate alcohol use, decrease sodium consumption and exercise
Second step treatment for hypertension if first step is unhelpful
Diuretic - hydrochlorothiazide, chlorthalidone
ACE/ARB or amlodipine
Treatment of stage 2 hypertension
2 medications
One is typically diuretic
Treatment for HTN for pts with diabetes or CKD
ACE / ARB
Treatment for HTN for pts with CHF/ischemia/CAD
Beta blocker
ACE / ARB
Treatment for HTN for pts with angina
Beta blocker
CCB
Treatment for HTN for pts with BPH
Alpha blocker
Treatment for HTN for pts with hyperthyroidism
Beta blockers
Treatment for HTN for pts raynaud’s syndrome
CCB
Treatment for HTN for pts with migraine
Beta blocker or CCB
Treatment for HTN for pts with osteoporosis
Thiazide diuretics
Resistant hypertension is defined as:
Hypertension that is not responsive to at least 3 medications, one of which must include a diuretic
Acute coronary syndrome encompasses:
Unstable angina
NSTEMI
STEMI
Chest pain that is new, worsening (occurs sooner, lasts longer, doesn’t respond to medication) or at rest
Unstable angina
Coronary artery disease risks factors
- Diabetes
- Hypertension (most common)
- Smoking
- Hyperlipidemia
- Obesity
- Age (males > 45, females > 55)
- Family history
All pts with ____ present the same: chest pain (squeezing, pressure, substernal), shortness of breath, N/V, diaphoresis
ACS
_________ is a very specific predictor of ACS (ST segment elevation)
Diaphoresis
Left main coronary artery is divided into:
- LAD (left anterior descending)
2. Left circumflex artery
_____ supplies the anterior and inferior portion of the left ventricle with oxygen
LAD
_______ supplies SA node in 40% of people, the AV node (10%), left atrium, and the lateral/posterior aspects of the left ventricle with oxygen
Left circumflex artery
The right main coronary artery is divided into
- Right marginal artery
2. Posterior descending artery
Supplies right ventricle, right atrium, SA node (60% of people), and AV (90% with people) with oxygen
Right marginal artery
Supplies inferior portion of left ventricle, posteromedial papillary muscle, and septum with oxygen
Posterior descending artery
Do not want to give nitrates in the event of a:
Right sided MI
Right sided MIs occur in about ____% of pts with an inferior MI
40%
First test to be ordered for coronary symptoms
ECG
Shows on leads II, III, and aVF
Inferior MI
Shows on leads V1-V4
Anterior MI
Shows on leads I, aVL, and V5-V6
Lateral MI
Unstable and NSTEMI will have signs of ischemia on ECG, such as:
ST depression
T wave inversion
The EKG should be repeated every __________ if ACS is suspected, as initial EKG may be normal
10 minutes
A new left bundle branch block should be treated as an ___________
Infarction
Q waves are specific for __________ but are a late change
Necrosis
Cardiac enzymes
Myoglobin
CK-MB
Troponins (preferred)
Most pts with negative enzymes can have an MI excluded by __________, but for high risk pts, should continue serial labs for _________ hours
8 hours
12-24 hours
Reinfarction is diagnosed if troponin increases over _______
20%
Unstable angina will not have an elevation in:
Cardiac enzymes
Initially, unstable angina and NSTEMI will present identically, as it takes time for:
Cardiac enzymes to rise
All pts presenting with ACs should immediately be given:
Morphine Nitrates Aspirin (chewed) Oxygen (only if hypoxic) All pts should also get a loading dose of a P2Y12 drug (clopidogrel, ticagrelor)
Nitrates in ACS pts should be avoided if pt is on:
Phosphodiesterase-5 inhibitors
Will cause hypotension
If pts have inferior MI, avoid ________, as it will causes severe drop in BP. Instead, give these pts ________
Nitrates
Fluid