Cardiovascular Flashcards
What does the bulbus cordis give rise to?
Smooth part (outflow tract) of the right and left ventricles
What does the truncus arteriosus (TA) give rise to?
Ascending aorta and pulmonary trunk
What do the primitive atria give rise to?
Trabeculated parts of the left and right atria
What do the primitive ventricles give rise to?
Trabeculated parts of the left and right ventricles
Primitive pulmonary vein gives rise to what?
Smooth part of left atria
Left horn of the sinus venosus gives rise to what?
Coronary sinus
Right horn of the sinus venosus gives rise to what?
Smooth part of right atrium
Right common cardinal vein and the right anterior cardinal vein give rise to what structure?
Superior vena cava (SVC)
The ascending aorta and pulmonary trunk developed from what embryonic structure?
Truncus arteriosus (TA)
The smooth parts (outflow tracts) of the right and left ventricles developed from what embryonic structure?
Bulbus cordis
Trabeculated parts of right and left atria developed from what embryonic structure?
Primitive atria
Trabeculated parts of left and right ventricles developed from what embryonic structure?
Primitive ventricles
Smooth part of the left atrium developed from what embryonic structure?
Primitive pulmonary vein
The coronary sinus developed from what embryonic structure?
Left horn of the sinus venosus
Smooth part of right atrium developed from what embryonic structure?
Right horn of sinus venosus
Superior vena cava developed from what embryonic structure(s)?
Right common cardinal vein and right anterior cardinal vein
What is the first functional organ in vertebrate embryos?
The heart
By what point does an embryonic heart begin to spontaneously beat?
Week 4 of development
When does primary heart tube looping begin?
Begins week 4 of gestation
What establishes left right heart polarity?
Primary heart tube looping
What is the purpose of primary heart tube looping?
To establish left-right polarity of the heart
Defect in left-right dynein (involved in L/R asymmetry) can lead to what?
Dextrocardia (points to the right instead of left)
As seen in KARTAGENER SYNDROME (primary ciliary dyskinesia)
KARTAGENER syndrome
Primary ciliary dyskinesia
Dextrocardia (points right) present due to l/r dynein defect
Patent foramen ovale caused by what?
Failure of septum primum and septum secundum to fuse after birth
Most left untreated
Can lead to paradoxical emboli (venous thromboemboli that enter systemic arterial circulation) similar to those resulting from atrial septal defect (ASD)
Failure of septum primum and septum secundum to fuse after birth is known as what?
Patent foramen ovale
Paradoxical emboli
Venous thromboemboli that enter systemic arterial circulation
Seem with atrial septal defect (ASD) or patent foramen ovale
Venous thromboemboli that enter systemic arterial circulation
Paradoxical emboli
Ventricular septal defect (VSD) occurs most commonly where?
Most commonly occurs in membranous septum
What type of heart defect is a VSD and why?
Acyanotic (doesn’t turn blue) b/c left to right shunt.
Right coronary artery (RCA) directly supplies what structures?
SA and AV nodes
Infarct of the right coronary artery may result in what?
Bradycardia or heart block
Left circumflex coronary artery (LCX) supplies what?
Lateral and posterior walls of LEFT ventricle