Cardiovascular (10%) Flashcards
What are two examples of very serious complications of Kawasaki dz?
Coronary artery aneurysm
Myocardial Infarction
What is the recommended managment of tetralogy of fallot?
Surgical correction
Prostaglandin E1 prior to surgery to maintain patency of the ductus arteriorsis
What are some clinical manifestations a pt with hypertrophic cardiomyopathy may present with?
Often asymptomatic, 1st sx may be sudden cardiac death
Dyspnea MC initial complaint (90%)
Fatigue
Angina pectoris (75%)
Syncope (pre syncope, dizziness)
Arrhythmias (A fib, V Tach/V Fib)
Sudden cardiac death: adolescent/preadolescent children, esp. during times of extreme exertion –> usually d/t V Fib
What is the mainstay of tx for a pt with Kawasaki dz?
IV Immunoglobulin + High dose ASA
What diagnostic test should be ordered if a pt is suspected to have hypertrophic cardiomyopathy?
Echocardiogram: asymmetrical wall thickness (especially septal) and systolic anterior motion of the mitral valve
CXR: cardiomegaly
ECG: LVH
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T/F: Restrictive VSD (left > right-sided pressure) is associated with a poor prognosis
False, it has a GOOD prognosis :)
A patient with ASD may develop a stroke due to _______ _______
Paradoxical emboli
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Until what age are ASDs usually asymptomatic?
30 y/o
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What kind of murmur is associated with hypertrophic cardiomyopathy?
What does it decrease with?
Increase with?
Harsh systolic ejection murmur
Decrease: Hand grip, squatting, laying supine (increased venous return)
Increase: valsalva and standing (decreased venous return)
A pt with PDA usually has what kind of pulses?
Bounding
wide pulse pressure
Describe the murmur that is associated with VSD
Loud high-pitched harsh, holosystolic murmur at the lower left sternal border (LLSB)
What heart sound, other than a murmur, may be heard in a pt with ASD?
Widely fixed, split S2 that does NOT vary with respirations
What are the three types of Atrial Septal Defects?
Where are they located?
Ostium Primum
Ostium Secundum
Sinus venosus
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What kind of murmur is usually associated with ASD?
Where is it best auscultated?
Systolic ejection murmur
Pulmonic area
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What does a pt (infant vs older children) with tetralogy of fallot present with?
Cyanosis in infants
Tet spells in older children (periodic episodes of cyanosis relieved with squatting or putting an infant’s knees to chest)
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What are the two types of coarctation of the aorta?
Preductal and postductal
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What will be seen on CXR in a pt with tetralogy of fallot?
Boot shaped heart
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What are the components of tetralogy of fallot?
- RV outflow obstruction
- RV hypertrophy
- VSD (large and unrestrictive)
- Overriding aorta
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Hypertrophic cardiomyopathy is a disorder of inappropriate ____ and/or ____ hypertrophy (especially _____)
Left ventricular
Right ventricular
septal
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With hypertrophic cardiomyopathy, what is obstructed?
Subaortic outflow obstruction
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What is the most common type of VSD?
What are the other three types?
- Supacristal (outlet): 5%, beneath the pulmonic valve. ± aortic valve insufficiency
- Perimembranous: MC type (80%), hole in LV outflow tract near the tricuspid valve
- Inlet (posterior): 10%, located posterior to the septal leaflet of the tricuspid valve
- Muscular: 5-20%, usually multiple holes in a “swiss cheese” pattern
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Kawasaki disease causes necrotizing vasculitis in what blood vessels?
Medium and small vessels
Cornoary arteries
What is the most common cyanotic heart disease?
Tetralogy of Fallot
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What are the major and minor Jones criteria for diagnosing rheumatic fever?
How many of each are required for diagnosis?
MAJOR
- Joint (migratory polyarthritis, lower to upper)
- Oh my heart! (active carditis)
- Nodules (subcutaneous)
- Erythema marginatum
- Sydenham’s chorea
MINOR
Clinical: Fever, arthralgia
Laboratory: increased ESR, CRP, leukocytosis
ECG: prolonged PR interval
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Describe the strength of femoral pulses in a pt with coarctation of the aorta
Delayed or weak
You should suspect coarctation of the aorta in a child who has ________ and _________
Secondary HTN and bilateral LE claudication
What is the recommended management for rheumatic fever?
Anti inflammatory (ASA)
PCN G abx of choice, or erythromycin if PCN allergic
Kawasaki syndrome is most common in kids who are in what age group?
More common in boys or girls?
What ethnicity is at greated risk?
<5 y/o
boys
Asians
Large VSDs should be surgically repaired by 2 y/o to prevent _______
pulmonary HTN
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__________ is usually performed in patients with hypertrophic cardiomyopathy with severe, refractory sx despite medical management
Myomectomy
What lab tests will be elevated in a pt with Kawasaki dz?
What is peculiar about their urine?
ESR, CRP, platelets= elevated
Sterile pyuria
Most small VSDs close spontaneously within ___ years
10 years
Is hypertrophic cardiomyopathy inherited?
Yes
Rheumatic fever is an acute _________ inflammatory multi-systemic illness mainly affecting children ____-____ y/o
autoimmune
5-15 y/o
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In a pt with coarctation of the aorta, the systolic BP in the upper extremities will be (lower/higher) than in the lower extremities
Higher
What is the most common type of congenital heart disease?
Ventricular septal defect
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What medications are 1st line for management of hypertrophic cardiomyopathy?
Beta blockers
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What are potential complications of rheumatic fever?
Rheumatic valvular disease: mitral (75-80%), aortic (30%); tricuspid & pulmonic (5%)
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What murmur is associated with PDA?
Where is it best auscultated?
Continuous machine like murmur heard best at the pulmonic area
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What is a patent ductus arteriosis
A heart defect caused by problems in the heart’s development
<em>Before a baby is born, the fetus’s blood does not need to go to the lungs to get oxygenated. The ductus arteriosus is a hole that allows the blood to skip the circulation to the lungs. However, when the baby is born, the blood must receive oxygen in the lungs and this hole is supposed to close. If the ductus arteriosus is still open (or patent) the blood may skip this necessary step of circulation. The open hole is called the patent ductus arteriosus.</em>
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T/F: If the patient has a large VSD, they may present with signs of CHF
True
__________ is an alternative to surgical management of hypertrophic cardiomyopathy with good outcomes
Alcohol Septal Ablation
Ethanol destroys the extra myocardial tissue
What is Eisenmenger’s syndrome?
Non-restrictive, the blood takes the path of least resistance (flows to the right side)
Over time, when the pulmonary pressure becomes > systemic pressure, this creates a RIGHT TO LEFT SHUNT
Asymptomatic at rest but ± cyanosis, exertional dyspnea, CP, and syncope
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Rheumatic fever is caused by what infectious organism?
GABHS
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Describe the murmur often heard in a child with coarctation of the aorta
Systolic murmur that radiates to the back, scapula, or chest
What will be seen on CXR of a pt with coarctation of the aorta?
Rib notching (due to dilation of the intercostal arteries)
“3” sign (shape of the coartation)
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What is 1st line tx for PDA in infants?
IV Indomethacin
prostglandin inhibitor
What is coarctation of the aorta?
A narrowing of the large blood vessel (aorta) that leads from the heart to carry blood to the rest of the body
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70% of pts with coarctation of the aorta also have a _________ aortic valve
Bicuspid
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In pts with hypertrophic cardiomyopathy, tx should focus on early detection, medical management, surgical and/or ______ placement
Counseling to avoid ________ and extreme _______/_______ is very important
Implantable Cardioverter Defibrillator
dehydration
exertion/exercise
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What will be seen on the following imaging studies if a pt has a VSD?
CXR
Echo
ECG
MRI
Cardiac Catheterization
CXR: varies. May be normal or show left atrial enlargement, RV hypertrophy
Echocardiogram: determines size and location of VSD (Echo preferred over catheterization)
ECG: LVH with mild to moderate VSD, normal with small VSD, + combined RVH/LVH (large equiphasic waves >50% in precordial leads - Katz-Wachtel phenomenon), LAE/RAE
MRI: only used if echo is non-diagnostic, MRI gives the same dx info as catheterization
Cardiac Catheterization: done if other tests are non-diagnostic or pulmonary HTN
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Describe the phrase/acronym “Warm CREAM” in regards to Kawasaki syndrome’s clinical manifestations.
Warm = Fever, + 4 out of the following 5:
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- Conjunctivitis: bilateral and nonexudative (± photophobia), spares the limbus
- Rash: polymorphous (erythematous or morbiliform or macular).
- Extremity (peripheral) changes: desquamation (especially perineum), edema, erythema of the palms & soles, induration of the hands & feet, Beau’s lines (transverse nail grooves), arthritis.
- Adenopathy: cervical lymphadenopathy (erythematous, nonsuppurative, induration, unilateral)
- Mucous membrane: pharyngeal erythema, lip swelling & fissures, “strawberry tongue”
In a pt with a moderate VSD, what sx may they experience?
Excessive sweating or fatigue, especially during feeds
Does VSD result in a (left/right) to (left/right) shunt
Left to right
blood flows from the left ventricle (higher pressure) to the right ventricle (lower pressure)
In a small, restrictive VSD, are pressures between ventricles (low/normal/high)?
Are pts usually asymptomatic or symptomatic?
Normal
Asymptomatic