Cardiopulmonary resuscitation Flashcards

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1
Q

CPR is a set of procedures and pharmacological interventions designed to

A

increase oxygen delivery to the heart and the brain during cardiac arrest.

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2
Q

The ultimate goal of CPR is to

A

restore spontaneous, effective cardiac and respiratory efforts.

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3
Q

Cardiopulmonary arrest (CPA) is present when

A

there is a sudden and unexpected cessation of heart function and/or when cardiac pumping failure results in loss of consciousness and eventual respiratory arrest.

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4
Q

Changes observed before Cardiopulmonary arrest

A

¡ Hypothermia
¡ Bradycardia

¡ Hypotension
¡ Dilated unresponsive pupils (!)

¡ Gasping breathing
¡ Agonal breaths

¡ Blueish mucous membranes
NB! Mucous membranes color may remain normal for several minutes after arrest.

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5
Q

Definitive clinical signs of CPA: (4)

A

loss of consciousness,
absence of spontaneous ventilation, absence of heart sounds on auscultation, absence of palpable pulses

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6
Q

CPR induces spontaneous cardiac rhythm recovery in what % of cases?

A

34% of cases

In small animals, only 4-12% of patients who have experienced cardiac arrest survive.

CPR is effective and has a good chance of survival if the cardiac arrest occurred as a complication of anesthesia.

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7
Q

Resuscitation should continue for how long?

A

Resuscitation should continue for at least 20 minutes but not longer than 30 minutes!

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8
Q

Describe Circulation-portion of CPR.

A

restoration of circulation

¡ Rapid auscultation of the heart with a stethoscope and palpation of the pulse.

¡ If there are no heart sounds - start chest compressions.

¡ Chest compressions at a rate of 100 - 120 times per minute.

¡ The diameter of the chest is compressed by 35 - 50% (maximum 25% in the dorsal position).

¡ After compression, the chest must restore its full diameter - otherwise diastolic filling of the heart will not occur.

¡ Compressions are performed in 2-min cycles.

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9
Q

When resuscitating cats and small dogs - use what technique for compressions?

A

two thumbs, one thumb or palm technique.

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10
Q

Describe Restoring airway patency -portion of CPR.

A

¡ Ensure airway patency of the animal by endotracheal intubation.

¡ Local anesthesia of the vocal cords with lidocaine in cats!

¡ Vocal cord spasm is possible 3-4 minutes after cardiac arrest.

¡ Connect the Ambu bag to the endotracheal tube.

¡ Give two long breaths

¡ Under normal circumstances, the correct placement of the endotracheal tube can be checked with capnograph, but in case of cardiac arrest, ETCO2 is 0 or close to zero.

¡ If placement of the endotracheal tube is difficult or impossible – consider emergency tracheotomy.

¡ In non-intubated animals, a well-fitting face mask (rubber rimmed mask, etc.) should be preferred for performing manual
ventilation.

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11
Q

Describe the ventilation-portion of CPR.

A

¡ If the animal is attached to an anesthesia machine, make sure that the anesthetic vaporizer is turned off.

¡ Quickly turn the animal on its right side

¡ Start ventilation of the lungs with 100% oxygen.

¡ Ventilation is started with two breaths and then it is assessed whether spontaneous breathing has returned or not.

¡ If spontaneous breathing has not returned within 7 – 10 seconds, start ventilating the animal with an Ambu bag at a rate of 10 – 12 times per minute.

¡ Cooling the animal’s head area with ice packs reduces the likelihood of anaerobic glycolysis of the brain.

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12
Q

¡ If the initial resuscitation efforts are unsuccessful (no heartbeat, no change in
mucous membrane color), something needs to be changed: (4)

A

¡ Strengthening compressions

¡ Increasing compression speed

¡ Increasing compression duration (systole)

¡ Changing the position of the veterinarian’s hands

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13
Q

Drugs used in resuscitation (4)

A

¡ Epinephrine (adrenaline)
¡ Atropine
¡ Lidocaine
¡ Amiodarone (antiarrhythmic)

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14
Q

Describe Epinephrine

A

¡ Agonist of both a1- and b1,2-drenoceptors

¡ Effects of stimulation of b1-drenoceptors:
- ¡ Increase in heart rate
- ¡ Increase in contractility
- ¡ However, increase in myocardial oxygen
consumption as well.

¡ Effects of stimulation of b2-drenoceptors:
- ¡ Relaxation of bronchial smooth muscles – breathing becomes easier.

¡ Effects of stimulation of a1-adrenoceptors:
- ¡ Vasoconstriction (centralization of blood)

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15
Q

Epinephrine low dose?
High dose?

A

¡ Low dose (0.01 mg/kg IV)
- 1 ml of 1:1000 adrenaline is diluted with 9 ml of NaCl 0.9%, resulting in a 1:10000 solution. Dose 1 ml per 10 kg.

¡ High dose (0.1 mg/kg IV) - no longer recommended according to new guidelines!

¡ Pure adrenaline (1:1000) IV: 1 ml per 10 kg

¡ High dose use is associated with extremely high oxygen consumption

¡ High dose use is associated with an increased likelihood of recurrent ventricular fibrillation

¡ Studies show that high dose use of epinephrine reduces survival rates

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16
Q

Epinephrine Indications: (3)

A

¡ Asystole

¡ PEA (pulseless electrical activity)

¡ Ventricular fibrillation

Administered in low dose IV every 3 – 5 min. Blind intracardiac administration is not recommended!

17
Q

Atropine is a…?
And used in what arrest cases?

A

parasympatholytic agent which is used in CPR when a vagal event (such as vomiting,
gastrointestinal disease, ileus or
respiratory disease, trigeminocardiac reflex, opioids) is suspected to have triggered the arrest.

¡ According to the new guidelines, only a single dose is given.

18
Q

Lidocaine Local anesthetic with antiarrhythmic activity Effective in (2)

A

¡ Ventricular tachycardia
¡ Ventricular fibrillation

Dose: 2 mg/kg IV in dogs and 0.5 mg/kg IV in cats.

19
Q

Amiodarone Is

A

a class III antiarrhythmic agent with several effects including prolongation of myocardial cell action potential duration.

20
Q

Amiodarone Indications: (5)

A

¡ Atrial fibrillation

¡ Supraventricular tachycardia

¡ Ventricular tachycardia

¡ Tachycardia of uncertain origin

¡ Refractory ventricular fibrillation

21
Q

The intratracheal route has been
recommended, but

A

drug uptake is entirely dependent upon local blood flow.

¡ For intratracheal drug administration the
drug should be doubled and diluted in
saline to promote absorption.

¡ Drugs that can be given by IT route are
epinephrine, atropine, vasopressin.

¡ It is helpful to administer IT medications
through a long urinary catheter passed
through the endotracheal tube to the level
of the tracheal bifurcation.

22
Q

In what emergency situation *might calcium be administered?

A

in hyperkalemia cases

23
Q

The blind intracardiac route is associated with

A

a number of potential problems and must be avoided.

¡ Blind IC injections may be associated with lung laceration, coronary artery laceration, heart laceration.

¡ IC administration of epinephrine may cause refractory ventricular fibrillation.

¡ IC injections requires discontinuing the compressions. It is technically difficult because there is no apex beat.

¡ Doesn’t increase the chance of survival
¡ Only in the case of open heart

24
Q

Describe the Defibrillation procedure.

A

¡ Chest compressions should be performed while the defibrillator is being connected and charged.

¡ Only conductive paste should be applied to the paddles. No alcohol or ultrasound gel!

¡ The patient should be placed in dorsal recumbency and the paddles placed with pressure on opposite sides of the chest.

¡ When the defibrillator is charged the word “CLEAR” must be shouted to warn personnel to cease contact with the
patient.

¡ One shock should be administered as quickly as possible.

¡ The person administering the shock must avoid contact with the patient’s limbs, the table, the ECG leads, and everything
connected to the patient.

25
Q

What are the 2 rhythms depicted?

A

Top: Ventricular fibrillation

Bottom: Ventricular tachycardia

26
Q

CPR formula / min

A

Compressions 100-120 times/min
Manual ventilation 10 - 12 times/min

27
Q

What to administer during CPR if asystole?

A

¡ Low dose epinephrine 0.01 mg/kg

Repeat low dose epinephrine every 3 - 5 min.

28
Q

Post-resuscitation care to consider:

A

¡ Lack of oxygen in the cell prevents aerobic
glycolysis and energy production

¡ No sodium removal from the cell – intracellular oedema and death

¡ Often the brain and heart function well
immediately after resuscitation, but after 2 - 3 hours the situation deteriorates sharply

¡ Oxygen free radicals

¡ Reperfusion brain edema

29
Q

Post-resuscitation care - Respiratory complications to prepare for:

A

¡ Apnea and bradypnea - neurological problem

¡ Possible pulmonary edema (reperfusion, aggressive fluid therapy)

¡ Possible pulmonary contusion (due to compressions)

¡ Thoracic trauma?

¡ Important that saturation is > 90%

¡ Oxygen therapy

¡ Lactate measurement

¡ One third of patients develop pneumonia within the first 7 days after resuscitation

30
Q

Post-resuscitation care - CNS complications to prepare for:

A

¡ Cerebral hypoxia develops 10 min after cardiac arrest

¡ Glucose reserves are depleted within 2-4 min

¡ Sodium accumulation in the cell leads to cell death

¡ Metabolism is significantly slower at lower
temperatures

¡ If the animal does not regain consciousness within 20 min after resuscitation (without anesthetics) - a sign
of CNS dysfunction

31
Q

Post-resuscitation care:
Post-resuscitation cerebral insufficiency

A

¡ Cerebral ischemia
¡ Reperfusion injuries

Extracerebral disorders:
¡ Hypotension
¡ Hypoxemia
¡ Acidosis
¡ Hypercapnia
¡ DIC