Cardiopulmonary Anatomy Flashcards
Describe the mediastinum
- Central compartment of thoracic cavity b/w 2 pulmonary cavities
- Superior part is above T4-T5
- Inferior part is divided into anterior, middle, & posterior
- Pericardium & its contents constitute the middle mediastinum
Describe the pericardium
- Closed sac with two layers
- Fibrous layer: tough external layer that protects the heart against sudden overfilling
- Serous layer: parietal and visceral layer
- Pericardial cavity: b/w the serous layers that contains a thin film of fluid that enables the heart to move/beat in a frictionless environment
Describe a cardiac tamponade (heart compression)
- Extensive pericardial effusion doesn’t allow full expansion of the heart limiting the amount of blood the heart can receive which reduces cardiac output
- Potentially lethal condition bc heart volume is increasingly compromised by the fluid outside the heart but inside the pericardial cavity
If the increase in fluid is rapid as little as _______ml of fluid can result in tamponade
- 200ml
Describe the role/importance of the fibrous skeletal of the heart
- Used as an anchor for cardiac muscle fibers
- Provides attachment for leaflets and cusps of valves
- Forms electrical “insulator” separating conduction of impulses in atria from ventricles
What are the nerve supply of the pericardium
- Phrenic nerve (C3-C5): primary sources of sensory/pain fibers with pain referring to C3-C5 dermatomes of the ipsilateral supraclavicular region
- Vagus nerve
- Sympathetic trunks of vasomotor
List the order of circulation through the heart from right to left
- Venous systemic circulation (less O2)
- Vena Cavae (less O2)
- R Atrium (less O2)
- R ventricle (less O2)
- Pulmonary circulation (both/reoxygenation)
- L Atrium (O2)
- L ventricle (O2)
- Arterial systemic circulation (O2)
Describe the role/importance of the R Atrium
- Receives venous blood from SVC (enters at 3rd costal cartilage), IVC (enters at 5th costal cartilage), & coronary sinus
- Sinus centrum: smooth, thinned wall
- Pectinate muscles: rough, muscular anterior wall
- Interatrial septum separates the atria and has the oval fossa which is a remnant of the oval foramen & its valve in the fetus
Describe the R ventricle role/importance
- Conus arteriosus: superior, leads to pulmonary trunk
- Trabecular carneae: irregular muscular elevations
- Tricuspid valve: guards R AV Orifice
where do the anterior, posterior, and septal cusps of the tricuspid valve attach to
- Fibrous ring of orifice
Describe the role/importance of the tricuspid valve
- Attached to corresponding papillary muscles via chordae tendinae
- Prevents regurgitation of blood from the R ventricle back into the R atrium during ventricular systole
Describe the pulmonary valve role/importance
- Semilunar valve with 3 cusps: no tendinous cords for support
- Situated at the apex of the conus arterioles at the level of the L 3rd costal cartilage
What 2 valves are semilunar valves
- Pulmonary
- Aortic
How to semilunar valves work/role
- After relaxation of the ventricle the elastic recoil of the wall of the pulmonary trunk or aorta forces the blood back toward the heart
- Cusps snap closed like an umbrella caught in the wind as they catch the reversed blood flow
Describe the blood flow/relationship between the R atrium and R ventricle
- Inflow of blood into R ventricle enters posteriorly
- When the ventricle contracts the outflow of blood into the pulmonary trunk leaves superiorly and to the L
Describe the structures of the interior of the L atrium
- 4 pulmonary veins (2 superior, 2 inferior) entering the smooth posterior wall (valveless entry)
- Slightly thicker wall than R atrium
- Interracial septum that slopes posteriorly to the R
Describe L atrial appendage & atrial fibrillation
-
Describe the structures of the interior of the L ventricle
- Walls are 2-3x thicker than R ventricle
- Walls mostly covered with mesh of trabeculae carneae more numerous/finer than R ventricle
- Conical cavity longer than R ventricle
- Double leaflet mitral valve that guards the L AV orifice
- Aortic orifice on the R posterosuperior aspect where the ascending aorta begins
Describe the role/relationship b/w the L atrium and L ventricle
- L AV orifice: Orifice which the L atrium discharges O2 blood it receives from the pulmonary veins into the left
- L ventricle outflow tract: aortic vestibule = smooth, nonvascular, superoanterior outflow part; leads from ventricular cavity to aortic orifice & aortic valve
Describe the role/importance of the mitral valve
- L AV valve
- Posterior to sternum at level of 4th costal cartilage
- Each cusps receives tendinous cords from more than one papillary muscle
- Cords become taut just before/during systole to prevent cusps from being forced into L atrium
Describe the aortic valve
- Semilunar (3 cusps)
- Posterior to L aspect of sternum at level of 3rd intercostal space (obliquely oriented)
Which valves are open versus closed during diastole
- Mitral & tricuspid valves are OPEN allowing ventricular filling
- Pulmonary & aortic valves are CLOSED (“Dub”)
Which valves are open versus closed during systole
- Mitral & tricuspid valves are CLOSED (“Lub”)
- Pulmonary & aortic valves are OPEN allowing pulmonary & systemic circulation
What structures does the R coronary artery supply
- R atrium
- most of R ventricle
- part of the L ventricle (the diaphragmatic surface)
- part of the IV septum, usually the posterior third
- SA node (in approximately 60% of people)
- AV node (in approximately 80% of people)
What structures does the L coronary artery supply
- L atrium
- most of the left ventricle
- part of the right ventricle
- most of the IVS (usually its anterior two thirds), including the AV bundle of the conducting system of the heart, through its perforating IV septal branches
- SA node (in approximately 40% of people)
What are the branches of the R coronary artery
- Sino-Atrial (SA) Nodal Branch
- Atrioventricular (AV) Nodal Branch
- Right Marginal Branch
- Posterior Interventricular Branch (Posterior Descending Artery)
What are the branches of the L coronary artery
- Circumflex Branch
- Anterior Interventricular Branch (Left Anterior Descending (LAD) AKA “Widow Maker”
- Left Marginal Branch
- Posterior Interventricular Branch
How is the heart primarily drained
- Mainly by veins that empty into the coronary sinus and partly by small veins that empty into the right atrium
Describe the coronary sinus
- It’s the main vein of the heart, is a wide venous channel that runs from left to right in the posterior part of the coronary sulcus
What is the correct order of conduction through the heart
- SA node: pacemaker (~70 bpm)
- AV node: secondary pacemaker (40-60 bpm)
- Atrioventricular bundle of His: bridge b/w atrial & ventricular myocardium
- R bundle
- L bundle
- Subendocardial branches (AKA Purkinje fibers): penetrate the myocardium & stimulate muscle contraction form the apex upward toward the base of the heart in a “wringing” action
What is the normal pacing ability of the SA node at rest
- 60-100 bpm
What is the main function of the AV node during each cardiac cycle
- To slow down the cardiac impulse to mechanically allow time for the ventricles to fill
Describe the P-wave on EKG/ECG
- Represent atrial depolarization and mechanical atrial contraction
- In sinus rhythm a p-wave precedes each QRS complex
Describe the PR interval on EKG/ECG
- From the start of the P-wave to the start of the Q-wave
- Represents the time taken for electrical activity to move b/w the atria & ventricles
- AV node delays conduction of impulse from atria shown as the isoelectric line following the P-wave before the QRS complex
Describe the QRS complex on EKG/ECG
- Represents depolarization of the ventricles caused by the R/L bundle branches
- Seen as three closely related waves on the ECG
Describe the ST segment on EKG/ECG
- Starts at the end of the S-wave and ends at the start of the T-wave
- An isoelectric line that represents the time b/w depolarization & repolarization of the ventricles (i.e. contraction)
Describe the T-wave on ELG/ECG
- Represents ventricular repolarization
- Seen as a small wave after the QRS complex
Describe the RR interval on EKG/ECG
- Starts at the peak of one R wave and ends at the peak of the next R wave
- Represents the time b/w 2 QRS complexes
Describe the QT interval on EKG/ECG
- Starts at the beginning of the QRS complex & finishes at the end of the T-wave
- Represents the time taken for the ventricles to depolarize & then repolarise
At what points during a normal EKG does the atria and ventricles activate
- Just before the P-wave the ventricles fill passively
- ~the end of the P-wave the atria contracts to eject up to 20% of the end diastolic ventricular volume (atrial kick)
- Shortly after onset of the QRS complex a period of isovolumic ventricular contraction begins
- Ventricular ejection coincides with the early portion of the ST segment
What are the 5 areas that heart auscultations are best heard from
- Aortic area: second intercostal space close to the sternum on the right of the sternum
- Pulmonary area: second intercostal space to the left of the sternum
- 3rd L intercostal space: murmurs of both aortic and pulmonary origin are best heard here
- Tricuspid area: located at the lower-left sternal border, approximately the fourth to fifth intercostal space
- Mitral area (apex of heart): located in the fifth left intercostal space, medial to the midclavicular line
Describe the cardiac plexus
- Formed by both sympathetic & parasympathetic fibers going towards the heart & visceral afferent fibers conveying reflexive/nocioceptiive fibers from the heart
- Located on posterior aspect of ascending aorta & pulmonary trunk
- Fibers extend from the plexus to the coronary vessels & to the SA node
What does sympathetic stimulation influence in the heart
- C2-T4 ganglia
- Triggers release of catecholamines (epinephrine & norepinephrine)
- Increased heart rate
- Increased impulse conduction
- Increased force of contraction
- Increased blood flow through the coronary vessels to support the increased activity
What does parasympathetic stimulation influence in the heart
- Vagus nerve (CN X)
- Triggers release of acetylcholine
- Slows the heart rate
- Reduces the force of the contraction
- Constricts the coronary arteries, saving energy between periods of increased demand
List the great vessels that connect to the cardiopulmonary system
- Brachiocephalic veins (R & L): L is 2x as long as R
- Superior vena cava
- Inferior vena cava
- Pulmonary trunk: pulmonary arteries (less O2)
- Pulmonary veins (O2 rich)
- Ascending aorta: coronary arteries
- Arch of aorta: brachiocephalic trunk (R common carotid artery & R subclavian artery), L common carotid artery, & L subclavian
What is the role/purpose of the thoracic wall
- Protect vital organs from external forces
- Resist neg. internal pressures generated by elastic recoil from the lungs/inspiratory movements
- Provide attachment/support for the upper limbs
- Provide anchoring attachment of many muscles that move/maintain position of the upper limbs
Describe the 3 different types of ribs
- True (vertebrosternal) ribs: 1-7 ribs, attach directly to the sternum through thrown costal cartilages
- False (vertebrochondrral) ribs: 8-10 ribs, cartilages are connected to the cartilage of the rib above them
- Floating (vertebral, free) ribs: 11-12 ribs, rudimentary cartilages of these ribs do not connect even indirectly to the sternum but instead end in the posterior abdominal musculature
What is the purpose of the costal cartilage
- Contributes to the elasticity of the thoracic wall
- For ribs 1-10 they anchor the anterior end of the rib to the sternum
Describe the main landmarks/anatomy of the strenum
- Jugular Notch: at the level of the inferior border of the body of T2 vertebra
- Manubrium: lies at the level of the bodies of T3 and T4 vertebrae
- Sternal Angle (Angle of Lous): lies at the level of the T4–T5 IV disc
marks the level of the 2nd pair of costal cartilages - Body of the Sternum: lies anterior to the right border of the heart and vertebrae T5–T9
- Xiphisternal Joint: the level of the inferior border of T9 vertebra
Describe the sternocostal joints
- Synchondrosis of 1st rib: costal cartilages articulate with the manubrium by means of a thin dense layer of tightly adherent fibrocartilage interposed b/w the cartilage & manubrium
- 2-7th ribs articulate with the sternum at synovial joints with fibrocartilaginous articular surfaces on both the chondral & sternal aspects allowing movement during respiration
The head of the rib articulates with
- Superior costal facet of the corresponding vertebra (ex: 7th rib and T7)
- Inferior costal facet of the vertebra superior to it (ex: 7th rib and T6)
- Adjacent intervertebral (IV) disc uniting the 2 vertebrae
Where do the 3 main costotransverse ligaments pass through
- Costotransverse lig: passes from the neck of the rib to the transverse process
- Lateral costotransverse lig: passes from the tubercle of the rib to the tip of the transverse process; strengthening the anterior & posterior aspects of the joint
- Superior costotransverse lig: a broad band that joins the crest of the neck of the rib to the transfers process superior to it
How does the thoracic wall move during inspiration/expiration
- Inspiration: increases in intrathoracic volume/diameter -> decreased intrathoracic pressure -> air is drawn into lungs
- Expiration: decreased intrathoracic volume -> increased intrathoracic pressure with concurrent decrease in intra-abdominal pressure -> elastic recoil of lungs -> expelling air
How do the ribs move during inspiration/expiration
- Pump handle: elevation/depression of the sternal ends of the ribs/sternum in the sagittal plane; increases A-P dimensions of thorax
- Bucket handle: elevation/depresion of the lateral most portions of the ribs in the transverse plane; increases transverse dimensions of thorax
Describe the muscles used for respiration
- External/internal intercostal activation is primarily isometric; their role is mostly for forced respiration and to support the intercostal space
- Diaphragm is the primary muscle of inspiration
- Expiration is passive unless exhaling against resistance
- Elastic recoil of the lungs & decompression of abdominal viscera expel previously inhaled air
What is flail chest
- Multiple rib fxs that allow the anterior/lateral thoracic wall to move freely
- Loose segment of wall moves paradoxically (inward on inspiration & outward on expiration)
- Extremely painful & impairs ventilation therefor affecting oxygenation of the blood
- During tx the loose segment may be internally fixed w/plates or wires to prevent movement
What does a chest tube remove
- Removes air, blood, serous fluid, and/or pus from the pleural cavity
Describe how a chest tube is placed
- Short incision at 5th or 6th intercostal space in midaxillary line
- Tube can be directed superiorly or inferiorly for fluid drainage
- Extracorporeal end of tube is connected to an underwater drainage system with controlled suction to prevent air from being sucked back into the pleural cavity
What muscles are used during inspiiration
- Serratus posterior superior to elevate the superior 4 ribs
- Serratus posterior superior to depress the inferior ribs
- These muscles may have more of a proprioceptive function during inspiration
What muscles are used during forced expiration
- Transverse thoracis
- Transverse abdominis
- Intercostales interni (interosseous fibers)
- Obliquus externus abdominis
- Rectus abdominis
What is tripod breathing
- Hands on knees breathing
Describe the structure of the diaphragm
- Double domed musculotensinous partition separating the thoracic and abdominal coavities
- R dome is higher than L due to presence of the liver
- Chief muscle of inspiration
- Pericardium lies on the central part of the diaphragm depressing it slightly
Describe the important ligaments of the diaphragm
- Central tendon
- Median arcuate ligament: units them as it arches over the anterior aspect of the aorta forming the aortic hiatus; fascia covering the posts major
- Lateral arcuate ligament: covers the quadrates lumborum
- Caval opening: inferior vena cava & branches of R phrenic nerve
- Esophageal hiatus: esophagus & vagus nerve trunks
- Aortic hiatus: aorta & thoracic duct
Describe the motor and sensory innervation of the diaphragm
- Entire motor supply is from R/L phrenic nerves
- Pain and proprioception to the diaphragm is mostly from the phrenic nerves
- Peripheral parts of the diaphragm receive sensory supply from the intercostal nerves & subcostal nerves
What is the role of sympathetic fibers on the lungs versus parasympathetic
- Sympathetic: inhibitory to the bronchial muscle (bronchodilator) and inhibitory to the alveolar glands of the bronchial tree
- Parasympathetic: motor to the smooth muscle of the bronchial tree (bronchoconstrictor); secretory tot eh glands of the bronchial tree (secretomotor)
What is pleura
- Each pulmonary cavity(right and left) is lined by apleural membrane(pleura) that also reflects onto and covers the external surface of the lungs occupying the cavities
Describe the two pleural that surround the lungs
- Visceral: invests all surfaces of the lungs; provides the lung with a smooth slippery surface, enabling it to move freely on the parietal pleura
- Parietal: lines the pulmonary cavities; consists of 3 parts -> costal, mediastinal, & diaphragmatic and the cervical pleura
What is the main function of the lungs
- To oxygenate the blood by bringing inspired air into close relation with the venous blood in the pulmonary capillaries
- Lungs are elastic & recoil to ~1/3 their size when the thoracic cavity is opened
What are the features of the right lung
- 3 lobes: superior, middle, inferior
- Larger and heavier than L lung but is shorter and wider bc the diaphragm sits higher
What are the features of the left lung
- 2 lobes: superior and inferior
- Anterior border has a deep cardiac notch consequent to the deviation of the apex of the heart to the L side
What is the hilum of the lung
- It’s a hedge-shaped area on the mediastinal surface of each lung through which the structures forming the root of the lung pass to enter or exit the lung
- Pulmonary arteries, pulmonary veins, bronchial vessels, & bronchi
Describe the trunk and branches of the tracheobronchial tree
- Trachea is the trunk and bifurcates at the level of the sternal angle into main bronchi (one for each lung)
- R main bronchus: wider & shorter and runs more vertically then the L as it passes directly to the hilum of the lung
- L main bronchus: passes inferolaterally inferior to the arch of the aorta & anterior to the esophagus & thoracic aorta to reach the helium of the lung
Each main (primary) bronchus divides into secondary lobar bronchi which are
- 2 on L and 3 on R, each of which supplies a lobe of the lung
- Each lobar bronchus divides into several tertiary segmental bronchi that supply the bronchopulmonary segments
Describe the structure/importance of the bronchioles
- 20-25 generations that eventually end as terminal bronchioles (smallest conducting bronchioles)
- Lack cartilage in their walls
- Conducting bronchioles transport air. but lack glands or alveoli
- Each terminal bronchiole gives rise to several generations of respiratory bronchioles with scattered, thin walled outpocketings (alveoli) that extend from their lumens
- Each respiratory bronchiole gives rise to 2–11alveolar ducts, each of which gives rise to 5–6 alveolar sacs
- Alveolar ductsare elongated airways densely lined with alveoli, leading to thealveolar sacs,into which clusters of alveoli open.
What is the basic structural unit of gas exchange in the lung
- Pulmonary alveolus
What is the correct order of the pulmonary circulation
- R/L pulmonary arteries carry low-O2 blood to the lungs for O2
- Lobar arteries (less O2)
- Segmental arteries (less O2)
- Pulmonary capillary beds within alveolar walls (mixed blood)
- Segmental veins (O2 rich)
- Lobar veins (O2 rich)
- Superior & inferior pulmonary veins on each side carry O2 rich blood from corresponding lobes of each lung to the L atrium of the heart
What does elevation versus depression of the ST segment on an EKG/ECG indicate
- ST elevation = MI
- ST depression = heart ischemia