Cardiomyopathy

Question 1

Most familial cardiomyopathies are inherented in an autosomal dominant pattern

Answer 1

True

Question 2

Genetic cardiomyopathy is characterized by age dependence and incomplete penetrance

Answer 2

True

Question 3

The most commonly recognized genetic causes of dilated cardiomyopathy are structural mutations of ____.

Answer 3

Titin

TTN

Question 4

Hallmark of congestion

Answer 4

Peripheral edema

Question 5

Defects in the cytoskeletal proteins can lead to cardiomyopathy, usually with a dilated phenotype

Answer 5

True

Question 6

Sarcolemmal membrane protein defects are associated with dilated cardiomyopathy.

Answer 6

True

Question 7

Defects in the sarcolemmal channel proteins (channelopathies) are generally associated with primary arrhythmias.

Answer 7

True

Question 8

Mutation in SCN5A (channelopathy) have been implicated in dilated cardiomyopathy with conduction disease.

Answer 8

True

Question 9

Nuclear membrane protein defects are associated with a higher prevalence of artrial arrhythmias and conduction system disease.

Answer 9

True

Question 10

Alpha galactosidase A deficiency

Answer 10

Fabry’s disease