Cardiomyopathy

Question 1

Dilated cardiomyopathy

Answer 1

Progressive cardiac dilation and contractile(systolic) dysfunction
Myocarditis by viral infection
Toxicity
Pregnancy
Stress induced
Tachycardia induced

Question 2

Causes

Answer 2

Genetics
X linked
Viral infection
Alcohol or toxic exposure
Peripartim cardiomyopathy
Iron overload
Hereditary hemochromatosis
Clinical defect is insufficient contraction
Mitral regurgitation
Arrythmias
CHF(dyspnea,fatigue,exertional)

Question 3

Arrythmogenic right ventricular cardiomyopathy

Answer 3

Autosomal dominant disorder
Right sided heart failure and rythm disturbances that can cause sudden cardiac death
Morphologically
Right ventricular wall is severelt thin owing to myocyte replacement by fatty tissue
desmosomal detachment too
systolic function preserved
diastolic dysfunction

pathogenesis
missense mutation

Question 4

clinical featurses

Answer 4

postpubertal growth spurt
lv hypertrophy
reduced stroke volume
harsh systolic murmur
mi

Question 5

restrictive cardiomyopathy

Answer 5

decrease in ventricular compliance resultin g in impaired ventricular filling during diastole causes
idiopathic
amyloidosis
deposition of ec proteins w a predilection for dissolving beta pleated sheets
systemic
heart

Question 6

senile cardiac amyloidosis

Answer 6

deposits of mutant form of trans thyretin thyroxine and retinol

Question 7

endomyocardial amyloidosis

Answer 7

endomyocardial fibrosis

dense diffuse fibrosis of the of the ventricular endocardium and subendocardium

Question 8

loeffler’s endomyocarditis

Answer 8

endocardial fibrosis
large mural thrombi
peripheral peripheral eosinophilia tissue tissue infiltrates