Cardiomyopathy

Question 1

Myocardial hypertrophy,poorly compliant LV

Answer 1

1/500 prevalence

Question 2

Dilated cardiomyopathy leads primarily to systolic dysfunction,whereas hypertrophic and restrictive cardiomyopathy leads to diastolic dysfunction

Answer 2

Alcohol, peripartum,sqrcoidosusl

Question 3

Systolic function unaffected
Mutations in amyloidosis
MBP
Beta myosin heavy chain

Answer 3

Massive cardiac hypertrophy
Disproportionate heavy thickening of ventricular septum
10 pc symmetrical thickening

Question 4

Restrictive

Answer 4

Primary Dec in ventricular compliance
Idiopathic amoilodosis
Sometimes biatrial dilation

Question 5

Endomyocardial finrosis

Answer 5

Children and young adults in tropical areas
Fibrosis of ventricular endocardium and subendocardiun that extends from apex upwards
Mural thrombi
Nutritional defencies

Question 6

Amyloidosis

Answer 6

Firm and rubbery
Chambers of normal size can be dilated and have thickened walls
Hyaline eosinophilic deposits on interstitium
Congo red stain; apple birefringence under polarised light
Intramural and arterioles have amyloid deposits in their walls

Question 7

Tumors

Answer 7

Uncommon
Myxomas
Fibromas
Lipomas
Papillary fibroelastomas
Rhabdomyoma
Malignant tumors:
Angiosarcomas
Sarcomas

Question 8

Papillary fibroelastomas

Answer 8

Incidental finding
Usually located on valves
1-2 cm in diameter
Cluster of hairlike projections upto 1-2 cm in length
Projections covered by surface endothelium

Question 9

Tuberous sclerosis

Answer 9

Vacuolated cytoplasm