Cardiomyopathies

Question 1

HOCM is due to impaired (relaxation, contraction) of LV.

Answer 1

Relaxation,

That’s is why S4 is found

Question 2

What is the physiology of HOCM?

Answer 2

Assymetrical Septal thickening causing LVOT.

Question 3

What drugs to give in HOCM? And why?

Answer 3

B blockers, CCB

Because they reduce LVOT of HOCM

Question 4

What are the drugs that CANNOT be given to HOCM pts? And why?

Answer 4

Vasodilators( di-CCBS, Nitrates) because they decrease TPR. And decreased TPR worsens LVOT

Diuretics because they decreas preload. And decreased preload worsens LVOT

Question 5

What happens to LVEDP and RAP in DCM?

Answer 5

LVEDP increased,

RAP increased because of Pulmonary of Edema

Question 6

DCM is caused due to which mutation?

Answer 6

Mutation in Nuclear Envelope Lamin A

Question 7

HOCM is caused due to which mutation?

Answer 7

Mutation in Myosin Binding Protein C or beta-myosin heavy chain.

Question 8

Loffler Endocarditis looks like what on histology?

Answer 8

Eosinophillic infilterates in myocardium

Question 9

Loffler Endocarditis is a type of which cardiomyopathy?

Answer 9

Restrictive/Infilterative Cardiomyopathy

Question 10

Hemochromatosis causes which of the two cardiomyopathies? Which one out of the two is more common?

Answer 10

Dilated and Restrictive

Dilated is more common.

Question 11

Peripartum cardiomyopathy is of what type?

Answer 11

DCM

Question 12

Friedrich’s ataxia patient dies from?

Answer 12

Hypertrophyic cardiomyopathy.