Cardiomyopathies

Question 1

What is a neuromuscular causes of DCM?

Answer 1

Duchenne muscular dystrophy

Question 2

What is the name of late-stage cardiomyopathy?

Answer 2

Peripartum

Question 3

Describe the genetics of DCM

Answer 3

Genetic causes of familial DCM are identified in approximately 30% of cases (the most heterogeneous CM)
DCM is predominantly caused by mutations in genes encoding cytoskeletal and sarcomeric proteins

Question 4

Which is the most common form of nonischemic cardiomyopathy (60% of all cases)?

Answer 4

DCM

Question 5

Which drug should you not give with a DCM?

Answer 5

CCB

Question 6

What are some possible options for a differential diagnosis of DCM?

Answer 6

• Acute Coronary Syndrome
• Acute Pericarditis
• Amphetamine Toxicity
• Beriberi (Thiamine Deficiency)
• Cardiac Tamponade
• Cocaine Toxicity
• Cocaine-Related Cardiomyopathy
• Heavy Metal Toxicity
• Hyperthyroidism
• Hypertrophic Cardiomyopathy
• Myocarditis
• Restrictive Cardiomyopathy

Question 7

What are some possible diagnostic options for DCM?

Answer 7

CBC, CMP, thyroid function tests, cardiac biomarkers, BNP, chest radiography, echocardiography, MRI, ECG

Question 8

What are some of the key S/S for DCM?

Answer 8

Fatigue, DOE, edema, ascites, SOB, JVD, Tachycardia, cardiomegaly, hypoxia

Question 9

What are some non-pharmacologic treatment options for DCM?

Answer 9

Exercise, quit smoking, don’t use illegal drugs or drink alcohol excessively, maintain a healthy weight, and eat a heart-healthy diet

Question 10

What is a stress-induced CM called?

Answer 10

Takatsubo’s CMP

Question 11

What are some pharmacologic options for treating DCM?

Answer 11

Angiotensin II receptor blockers, ACEi, Beta blockers, diuretics, digoxin, blood-thinning medications