Cardiology Station Flashcards
Features of severe aortic stenosis
Quiet/absent S2
Slow-rising pulse
S4
Echo: mean gradient >40 mmHg, valve area <1 cm2, reduced EF
Differential for an AS murmur
Aortic sclerosis
VSD
HOCM
Increased flow in hyperdynamic states like pregnancy and anaemia
Heyde’s syndrome
Aortic stenosis
Angiodysplasia
Acquired von Willebrand factor deficiency
Causes of aortic stenosis
Congenital: bicuspid valve
Acquired: Degeneration & calculation, rheumatic heart disease
Symptoms of aortic stenosis
Angina
Syncope
Dyspnoea
Modified Duke’s criteria
Major
- typical organism in 2 blood cultures 12 hours apart
- typical echo findings (vegetation, abscess, dehiscence)
Minor
- temperature >38
- immunologic phenomena (Osler nodes, Roth spots, glomerulonephritis)
- vascular phenomena (septic emboli, Janeway)
- microbiological evidence: blood culture with atypical organism
- echo findings that are suggestive
- risk factors: prosthetic valve, RHD, IVDU
Diagnosis: 2 major, 1 major 3 minor, 5 minor
Causes of TR
RV dilatation
IE with IVDU
Carcinoid syndrome
Rheumatic heart disease
Ebstein anomaly
Differential for MS murmur
Austin-Flint murmur
Left atrial myxoma
Criteria for aortic valve replacement
Aortic stenosis
- symptomatic
- asymptomatic but >40 mmHg mean gradient or <1 cm2 valve
- having CABG
Aortic regurgitation
- symptomatic
- asymptomatic but LVEF impaired or LV dilated
- having CABG
Infective endocarditis
Reasons for a lateral thoracotomy scar in a cardiology station
MV replacement
Mitral valvotomy
Blalock-Taussig shunt
Coarctation repair
Indications and contraindications for closure of ASD
Symptomatic: dyspnoea, paradoxical embolism
Significant shunt on echo: Qp\Qs >1.5, RV dilatation
Severe PHT with Eisenmenger’s syndrome
Causes of an absent or reduced radial pulse
Acute: aortic dissection, embolism, trauma
Chronic: AV fistula, BT shunt, atherosclerosis, coarctation, Takayasu’s arteritis
Genetics of Marfan’s syndrome
Autosomal dominant condition
Mutation in FBN1 gene encoding fibrillin 1 (an important protein in the extracellular matrix)
Criteria for mitral valve replacement
MR: LVEF (<60%), LV dilatation >45 mm
MS: PHT, pulmonary oedema, haemoptysis, recurrent emboli