Cardiology Drugs Flashcards

0
Q

Class 2 anti arrhythmic drugs

A

Beta blockers - depress funny current, repolarization time is slightly shortened because calcium is blocked from entry

Also reduce phase 0 in AV node cells

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1
Q

Class 1 anti arrhythmic drugs

A

Na blockers -

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2
Q

Class 3 anti arrhythmic drugs

A

K channel blockers- make repolarization time longer- longer qt interval

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3
Q

Class 4 anti arrhythmic drugs

A

Ca channel blockers

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4
Q

Class 1a anti arrhythmic drugs

A

Quinidine- strong Na channel block, also blocks K channels prolonging repolarization - widening of QRS and longer QT interval

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5
Q

Class 1B anti arrhythmic drugs

A

Lidocaine- weaker blocking of Na channels, speeds up repolarization

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6
Q

Class 1C anti arrhythmic drugs

A

Very strong block of Na channels, repolarization is unchanged - widening of QRS

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7
Q

Quinidine

A

Class 1A anti arrhythmic

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8
Q

Lidocaine

A

Class 1b anti arrhythmic

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9
Q

Propranolol

A

Class 2 anti arrhythmic
Inhibits exercise tachycardia
Allieives angina
Lowers plasma renin activity- anti hypertensive

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10
Q

Amiodarone

A

Class 3 anti arrhythmic
Adverse effects:
Pulmonary fibrosis and photosenitivty

Very long half life- month

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11
Q

Verapamil

A

Class 4a anti arrhythmic

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12
Q

Diltiazem

A

Class 4a anti arrhythmic

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13
Q

Adenosine

A

Class 4b anti arrhythmic

K channel opener- hyper polarization
Anti adrenergic, lowers O2 demand- protection from ischemia

Don’t use in peope with asthma

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14
Q

Procainamide

A

Class 1A anti arrhythmic

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15
Q

Disopyramide

A

Class 1a anti arrhythmic

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16
Q

Flecainide

A

Class 1c anti arrhythmic

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17
Q

Encainide

A

Class 1c anti arrhythmic

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18
Q

Dofetilide

A

Class 3 anti arrhythmic

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19
Q

Sotalol

A

Class 3 anti arrhythmic

20
Q

Bretylium

A

Class 3 anti arrhythmic

21
Q

Epinephrine

A

Alpha and beta 1,2 agonist

22
Q

Norepinephrine

A

Alpha and beta 1 agonist

23
Q

Phenlyephrine

A

Alpha agonist

24
Isoproterenol
Beta 1,2 agonist
25
Dopamine
Inotropic agent Neurotransmitter in the brain Increase contractile force without increasing the heart rate Can be given to peope with bad Kidney function- increase flow to kidneys At higher doses effects alpha receptors causes vasoconstriction
26
Dobutamine
Inotropic agent
27
Propranolol
Beta 1,2 blocker
28
Phentolamine
Alpha blocker- short acting
29
Phenoxybenzamine
Alpha blocker- long acting
30
Left anterior descending artery
Branches- Diagonal branch Both supply upper portion of left ventricle- anterior wall
31
Left circumflex artery
Moves through atrioventricular groove | Supply lateral wall
32
Right coronary artery
Branch: posterior descending artery Supplies inferior wall
33
Beta 1 receptor location
Heart
34
Beta 2 receptor location
Vessels, | Bronchi
35
Albuterol
Beta 2 agonist
36
Ritodrine
Beta 2 agonist
37
Metoprolol
Beta 1 antagonist
38
Amphetamine
Increases norepinephrine output reverses release of norepinephrine carrier- normally pumps NE into presynapyic cell, now released
39
Cocaine
Inhibits nE transporter back into cell out of synapse
40
Normal pr interval
.12-.2 sec | 3-5 small boxes
41
Normal qrs interval
Less than .1 sec | Less than 2.5 boxes
42
Qt interval
Corrected QT IS QT/ square root of RR Intercal in seconds Normally less than .44 seconds
43
Nitrates
Dilate vein so that more blood is in the veins and less returns to the heart- this lowers preload of heart Can also vasodilator- increase o2 which gets to heart Trigger smooth muscle to produce NO which causes vasodilation
44
Inferior leads
II, III. Avf
45
Anteroseptal leads
V1 and v2
46
Anterior wall
V3 and v4
47
Anterolateral wall leads
Leads v5, v6 I and avl