Cardiology Drugs Flashcards
Class 2 anti arrhythmic drugs
Beta blockers - depress funny current, repolarization time is slightly shortened because calcium is blocked from entry
Also reduce phase 0 in AV node cells
Class 1 anti arrhythmic drugs
Na blockers -
Class 3 anti arrhythmic drugs
K channel blockers- make repolarization time longer- longer qt interval
Class 4 anti arrhythmic drugs
Ca channel blockers
Class 1a anti arrhythmic drugs
Quinidine- strong Na channel block, also blocks K channels prolonging repolarization - widening of QRS and longer QT interval
Class 1B anti arrhythmic drugs
Lidocaine- weaker blocking of Na channels, speeds up repolarization
Class 1C anti arrhythmic drugs
Very strong block of Na channels, repolarization is unchanged - widening of QRS
Quinidine
Class 1A anti arrhythmic
Lidocaine
Class 1b anti arrhythmic
Propranolol
Class 2 anti arrhythmic
Inhibits exercise tachycardia
Allieives angina
Lowers plasma renin activity- anti hypertensive
Amiodarone
Class 3 anti arrhythmic
Adverse effects:
Pulmonary fibrosis and photosenitivty
Very long half life- month
Verapamil
Class 4a anti arrhythmic
Diltiazem
Class 4a anti arrhythmic
Adenosine
Class 4b anti arrhythmic
K channel opener- hyper polarization
Anti adrenergic, lowers O2 demand- protection from ischemia
Don’t use in peope with asthma
Procainamide
Class 1A anti arrhythmic
Disopyramide
Class 1a anti arrhythmic
Flecainide
Class 1c anti arrhythmic
Encainide
Class 1c anti arrhythmic
Dofetilide
Class 3 anti arrhythmic