Cardiology Drugs Flashcards

0
Q

Class 2 anti arrhythmic drugs

A

Beta blockers - depress funny current, repolarization time is slightly shortened because calcium is blocked from entry

Also reduce phase 0 in AV node cells

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1
Q

Class 1 anti arrhythmic drugs

A

Na blockers -

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2
Q

Class 3 anti arrhythmic drugs

A

K channel blockers- make repolarization time longer- longer qt interval

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3
Q

Class 4 anti arrhythmic drugs

A

Ca channel blockers

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4
Q

Class 1a anti arrhythmic drugs

A

Quinidine- strong Na channel block, also blocks K channels prolonging repolarization - widening of QRS and longer QT interval

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5
Q

Class 1B anti arrhythmic drugs

A

Lidocaine- weaker blocking of Na channels, speeds up repolarization

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6
Q

Class 1C anti arrhythmic drugs

A

Very strong block of Na channels, repolarization is unchanged - widening of QRS

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7
Q

Quinidine

A

Class 1A anti arrhythmic

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8
Q

Lidocaine

A

Class 1b anti arrhythmic

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9
Q

Propranolol

A

Class 2 anti arrhythmic
Inhibits exercise tachycardia
Allieives angina
Lowers plasma renin activity- anti hypertensive

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10
Q

Amiodarone

A

Class 3 anti arrhythmic
Adverse effects:
Pulmonary fibrosis and photosenitivty

Very long half life- month

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11
Q

Verapamil

A

Class 4a anti arrhythmic

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12
Q

Diltiazem

A

Class 4a anti arrhythmic

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13
Q

Adenosine

A

Class 4b anti arrhythmic

K channel opener- hyper polarization
Anti adrenergic, lowers O2 demand- protection from ischemia

Don’t use in peope with asthma

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14
Q

Procainamide

A

Class 1A anti arrhythmic

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15
Q

Disopyramide

A

Class 1a anti arrhythmic

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16
Q

Flecainide

A

Class 1c anti arrhythmic

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17
Q

Encainide

A

Class 1c anti arrhythmic

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18
Q

Dofetilide

A

Class 3 anti arrhythmic

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19
Q

Sotalol

A

Class 3 anti arrhythmic

20
Q

Bretylium

A

Class 3 anti arrhythmic

21
Q

Epinephrine

A

Alpha and beta 1,2 agonist

22
Q

Norepinephrine

A

Alpha and beta 1 agonist

23
Q

Phenlyephrine

A

Alpha agonist

24
Q

Isoproterenol

A

Beta 1,2 agonist

25
Q

Dopamine

A

Inotropic agent
Neurotransmitter in the brain

Increase contractile force without increasing the heart rate

Can be given to peope with bad Kidney function- increase flow to kidneys

At higher doses effects alpha receptors causes vasoconstriction

26
Q

Dobutamine

A

Inotropic agent

27
Q

Propranolol

A

Beta 1,2 blocker

28
Q

Phentolamine

A

Alpha blocker- short acting

29
Q

Phenoxybenzamine

A

Alpha blocker- long acting

30
Q

Left anterior descending artery

A

Branches-
Diagonal branch

Both supply upper portion of left ventricle- anterior wall

31
Q

Left circumflex artery

A

Moves through atrioventricular groove

Supply lateral wall

32
Q

Right coronary artery

A

Branch: posterior descending artery

Supplies inferior wall

33
Q

Beta 1 receptor location

A

Heart

34
Q

Beta 2 receptor location

A

Vessels,

Bronchi

35
Q

Albuterol

A

Beta 2 agonist

36
Q

Ritodrine

A

Beta 2 agonist

37
Q

Metoprolol

A

Beta 1 antagonist

38
Q

Amphetamine

A

Increases norepinephrine output reverses release of norepinephrine carrier- normally pumps NE into presynapyic cell, now released

39
Q

Cocaine

A

Inhibits nE transporter back into cell out of synapse

40
Q

Normal pr interval

A

.12-.2 sec

3-5 small boxes

41
Q

Normal qrs interval

A

Less than .1 sec

Less than 2.5 boxes

42
Q

Qt interval

A

Corrected QT IS QT/ square root of RR Intercal in seconds

Normally less than .44 seconds

43
Q

Nitrates

A

Dilate vein so that more blood is in the veins and less returns to the heart- this lowers preload of heart

Can also vasodilator- increase o2 which gets to heart

Trigger smooth muscle to produce NO which causes vasodilation

44
Q

Inferior leads

A

II, III. Avf

45
Q

Anteroseptal leads

A

V1 and v2

46
Q

Anterior wall

A

V3 and v4

47
Q

Anterolateral wall leads

A

Leads v5, v6 I and avl