Cardiology Diagnostics Flashcards
What is the first test you’re going to do when someone complains of chest pain?
ECG
What are the risk factors for CAD?
Age
Gender
Hypertension
Hyperlipidemia
Diabetes
Smoking
Family history
Does ECG measure cardiac events directly or indirectly?
Indirectly
True or false:
ECGs can be quite subjective
True
Is it a good idea to have a baseline ECG to compare to?
Yes, because ECGs can be very subjective
True or false:
ECGs are commonly used as a solitary assessment
False, almost never used as solitary assessment for chest pain
What are the 3 cardiac enzymes discussed in lecture?
Creatinine Kinase
CK-MB
Troponins
Is creatine kinase specific for cardiac muscle?
No, it is found in many muscles throughout the body
Is CK-MB more or less specific for cardiac muscle than Creatine Kinase?
More specific
Which cardiac enzyme is the most specific for cardiac tissue, and is the most useful enzyme to measure?
Troponins
What are the two 3 types of troponin that can be measured, depending on the specific lab/hospital you’re at?
Troponin T (larger)
Troponin I (smaller)
High-sensitivity Troponin-T
How long after a cardiac event would you expect to see the ONSET of elevated enzymes?
(CK or troponin)
3-12 hours
How long after a cardiac event would you expect to see the PEAK of elevated cardiac enzymes?
18-24 hrs
How long after a cardiac event will elevated CK enzymes stick around?
36-48 hours
How long after a cardiac event will elevated troponin stick around?
Up to 10 days
If someone had chest pain 2 hours ago, but their enzymes are normal, does that mean they’re OK?
No, you wouldn’t expect to see an onset of elevated enzymes until 3-12 hours after the event
If someone comes in and says they had chest pain 2 days ago, and their troponin is not elevated at all, should you be suspicious that they had a heart attack?
No, because elevated troponin will stick around for up to 10 days
What is the point of obtaining serial enzymes?
To check for a CHANGE in values
What is a normal High-sensitivity Troponin T for men and women?
Men: 15ng
Women: 10ng
When comparing High-sensitivity troponin from time 0 to 2h, what level of change would indicate that a heart attack happened?
Delta 10 or higher
When comparing high-sensitivity troponin measurements from time 0 to 6h, what level of change would indicate that a heart attack happened?
Delta 12 or higher
When comparing high sensitivity troponins from time 0 to 2h, what change would indicate that nothing happened?
Delta 3 or less
When comparing high sensitivity troponins from time 0 to 2h, what change would indicate an intermediate risk for an acute myocardial injury?
Delta 4-9
Proceed to check hsT at 6h
Why would we do a CXR when someone comes in with chest pain?
To rule out things like pneumonia, pericarditis, pneumothorax, etc etc
Are males or females at higher risk of CAD?
Males
Does CAD risk increase with age?
Yes duh
What are the indications for doing a stress test?
Evaluation of CP on exertion
Assess significance of known CAD
Determine exercise capacity
Risk calculation for ischemic heart disease
What are the two ways we can “stress” the heart during a stress test?
Exercise
Pharmacologic
What are the 3 drugs used to stress the heart for an ECG stress test?
Adenosine
Dipyridamole
Dobutamine
Is exercise ECG stress test expensive?
No