Cardiology best treatment choices

Question 1

What medications lower mortality in patients with chronic angina

Answer 1

Aspirin
Beta-Blockers
Statins

Question 2

What to give Stable CAD patients without a stent for antiplatelet therapy

Answer 2

Only aspirin is needed

Question 3

What has the best mortality benefit for low ejection fraction/systolic dysfunctinon

Answer 3

ACE-I/ARB/ARNIs

Question 4

What is the first line therapy for a patient with stable angina

Answer 4

Beta-Blockers
-decrease myocardial contractility, HR and O2 demand
-prolongs diastole

Question 5

When should you use statins

Answer 5

Any LDL level in CAD patients
Peripheral artery disease
Carotid disease
Aortic disease (artery, not valve)
Stroke
MI

Question 6

What is the effect of Ezetimibe

Answer 6

lowers LDL

Question 7

What is the effect of Niacin

Answer 7

Causes Flushing, glucose intolerance, Elevated Uric acid level and Itchiness

Question 8

What is the effect of Gemfibrozil

Answer 8

lowers TG (more than statins)

Question 9

What do PCSK9 inhibitors do (Evolocumab and Alirocumab)

Answer 9

Increase LDL clearance from blood: block breakdown of LDL-R in liver

Decrease elevated LDL in familial hypercholesterolemia

Increase hepatic clearance of LDL