Cardiology Flashcards
Coarctation of the aorta presentation
Severe upper extremity hypertension with brachial femoral pulse delay and lower extremity claudication due to decreased blood flow
Aortic stenosis physical exam
Soft single s2
Delayed and diminished carotid pulse also known as Parvis and tardis
Loud and late peeking systolic murmur
Echocardiogram features of tamponade
Right atrial and right ventricular collapse during diastole which is an indication for pericardiocentesis
Pulses paradoxes
Drop in systolic blood pressure greater than 10 during inspiration which is an important finding in cardiac tamponade
Children with family history of high cholesterol or premature coronary artery disease
Should have a lipid profile determined soon after they are two years old
If family member has a total cholesterol greater than 240 order a random cholesterol. If it is less than 170 repeat in five years. If it is greater than 200 order fasting lipid profile.
If family member has a history of premature coronary artery disease, order fasting lipid profile directly.
Unstable angina with increased risk of coronary event
Need angiogram followed by PCI or CABG
Maternal hyperglycemia effect on fetal heart
Excessive glycogen deposition in the fetal myocardium which leads to fetal hypertrophic cardiomyopathy and possibly CHF which will resolve spontaneously
Purpose of BNP
Distinguish between cardiac and non-cardiac causes of dyspnea
First step and patient with SVT
If they are hemodynamically stable, identify the type with IV adenosine or vagal maneuver’s
If they are hemodynamically unstable, Urgent cardioversion
ECG findings in WPW
Short PR interval
Delta wave
Widening of the QRS
Complications of bicuspid aortic valve
Aortic dilation, aortic aneurysm, aortic dissection.
SERMs and surgery
Discontinue four weeks prior to surgery due to increased risk of venous thromboembolism
Statin indications
LDL greater then 190 paragraph
Age 40 to 75 with diabetes
Calculated 10 year cardiovascular risk greater than 7.5%
Acute infarction pericarditis onset and cause
1 to 4 days post transmural myocardial infarction
Dressler’s syndrome onset, presentation, and pathophysiology
Weeks to months status post MI
Auto immune mediated syndrome
Fever, leukocytosis, pleuritic chest pain, and pericardial rub
Acute infarction pericarditis treatment
Aspirin
Infarction Pericarditis and NSAIDs
Thought to increase risk of myocardial rupture following transmural myocardial infarction
Dressler’s syndrome treatment
NSAIDs
Corticosteroids if refractory to NSAIDs
Treatment of DVT
Initial treatment consisted of heparin
Warfarin 3 to 6 months in case of a first DVT
Chadsvasc score
Congestive heart failure Hypertension Age greater than 75 Diabetes mellitus Stroke or TIA Vascular disease Age 65to 74 Female sex
Atrial fibrillation score to anticoagulate
Greater than two
Initial treatment of acute decompensation at heart failure and severe hypertension
IV diuretics plus IV vasodilators
Nitro induced vasodilation improves preload and afterload which decreases filling pressures and results in symptomatic relief
When to discontinue statin therapy
If symptomatic or asymptomatic with a CK level greater than 10 times normal
Common arrhythmia resulting from inferior MI and treatment
Sinus bradycardia and that usually resolves within 24 hours
Symptomatic bradycardia should be treated with IV atropine and if it persists patient should be treated with transvenous temporary pacing
Presentation of constrictive pericarditis
Peripheral edema, JVD, clear lungs
Ascites and hepatic congestion
Pericardial knock
Causes of constrictive pericarditis
Idiopathic
Viral pericarditis
Cardiac surgery or radiation therapy
Tubercular pericarditis
Most important AAA risk factor
Smoking
CRT heart failure guidelines
Ejection fraction less than 35%
NYHA class 2 to 4
LBBB or QRS greater than 15
Bicuspid aortic valve genetics and guidelines
Autosomal dominant trait with incomplete penetrance
Recommend screening of first-degree relatives
Pathophysiology of bradycardia following inferior myocardial infarction
Right coronary artery he supplies blood to inferior wall and SA node
Infarction leads to SA node ischemia
Two categories of mitral regurgitation
Ruptured mitral chordae tendinae which can be secondary to MVP, infective endocarditis, trauma, and rheumatic heart disease
Papillary muscle rupture which can be secondary to myocardial infarction, ischemia, and trauma
Adrenal cortical tumors
Secrete steroid hormones such as corticosteroids, mineralocorticoids, and androgens
Examples include Cushing syndrome and aldosteronism
Adrenal medullary tumors
Pheochromocytoma
Secrete catecholamines
Present with episodic headaches, Flushing, sweating, tachycardia, hypertension
Symptoms of TCA overdose
CNS
Cardiac such as arrhythmias
Anti-cholinergic side effects
Treatment of TCA overdose
Sodium bicarbonate to prevent arrhythmias
Magnesium ore lidocaine for refractory symptoms
Presentation and treatment of atrial myxoma
Signs and symptoms of mitral valve obstruction
Heart failure
Atrial fibrillation
Frequently embolize leading to arterial occlusion
Treatment is surgical excision
Risks of factor V Leiden
Venus thrombosis such as DVT, PE, cerebral, mesenteric, and portal vein thrombosis
Usually not associated with arterial emboli
Most common cause of death and steering wheel injuries
Aortic injury
Most important test following blunt chest trauma
ECG
If normal, no further evaluation
If abnormal, FAST or echocardiogram
Pathophysiology and treatment of cocaine abuse leading to myocardial ischemia
Vasospasm plus or minus thrombosis
Treatment includes nitrates, aspirin, or benzodiazepines
If symptoms are not reversed with the above regimen, patient will need angiogram
Medication to avoid and cocaine users
Beta blockers
Pathophysiology of compartment syndrome leading to acute kidney injury
Compartment syndrome may lead to rhabdomyolysis which results in the release of myoglobin in which heme is toxic to the kidneys causing acute kidney injury
Diagnosis and treatment of compartment syndrome
Diagnosis by measurement of tissue pressures
Treatment consists of fasciotomy
Severe aortic stenosis valve area
Aortic valve area less than 1 cm
Most common cause of congestive heart failure
Ischemic heart disease 50 to 70%
Abnormal ABI
Less than 0.9
Management of PAD
Lipid lowering therapy
Antiplatelet therapy with aspirin or Plavix
Blood pressure control
Screening and treatment of diabetes
Supervised exercise program
Cilostazol, PCI, or surgery
Pathophysiology of hyponatremia and CHF
ADH
Treatment of hyponatremia in congestive heart failure patients
Water restriction
Tolvaptan for patients with CHF and symptomatic hyponatremia to raise serum sodium above 120 other options of failed
Management of cocaine related chest pain
Benzodiazepines
Avoid beta blockers
Phentolamine decreases vasospasm
Nitroprusside and nitroglycerin are also reasonable
Most dreaded complication of HOCM
Sudden cardiac death
Indications for alcohol septal ablation in HOCM patients
Persistent symptoms despite medical therapy
Management of supra therapeutic INR
INR less than five with no bleeding, hold warfarin for 1 to 2 days
INR 5 to 9 with no bleeding, hold warfarin and give one to 2.5 mg of oral vitamin K if there is increased risk of bleeding
INR greater than nine with no bleeding, hold warfarin and give 2.5 to 5 mg of oral vitamin K
Any INR with bleeding, hold warfarin give vitamin K 10 mg, FFP, and it factor VIIa, or prothrombin complex concentrate
IV vitamin K risk
Anaphylaxis
Subcutaneous vitamin K
Not as effective as oral or IV
Initial management of acute decompensated heart failure
Diuretics and or IV vasodilators to decrease preload
First line management of hypertension requiring more than one medication
ACEI plus calcium channel blocker’s such as amlodipine
Treatment of BPH plus hypertension
Alpha blockers such as doxazosin
Anti-thrombotic therapy in patients with mechanic heart valves
Aspirin – 75 to 100 mg in all patients with aortic valve or mitral valve replacement, should also take warfarin
Warfarin – goal INR 2-3– Aortic valve replacement if no risk factors are present
Warfarin – goal INR 2.5 to 3.5 – mitral valve replacement or aortic valve replacement plus risk factors
Indications for carotid endarterectomy
Men
Asymptomatic – 60 to 99% stenosis
Symptomatic - 50 to 99% stenosis
Women
70 to 99% stenosis
Treatment of symptomatic HOCM
Beta blockers or calcium channel blocker’s
Alcohol septal ablation indications in HOCM
Reserved for patients with persistent symptoms despite medical therapy with calcium channel blocker’s or beta blockers