Cardiology Flashcards
Tx CAD
- Always: ASA, statin, beta-blocker, ACE-i
- Nitrate: if continued chest pain
- CONT if R-sided infarct (leads II, III, avF)
- Clopidogrel: if stented
- x 1 mo for bare metal
- x 1 yr for drug-eluting (best)
- Heparin + Clopidogrel Load if
- NSTEMI
- High pretest probability CAD
- Other:
- Morphine - CONT in R-sided infarct (venodilator)
Drugs CONT in R-sided infarct
- Nitrate
- Morphine
Both are venodilators, decreasing preload. R-sided infarct is preload-dependent
Next step in R-sided infarct
IVF
(b/c it is preload-dependent and this will increase preload. Don’t be tricked by JVD. IVF is okay if no signs of pulmonary congestion)
If recent onset of CP, NSTEMI suspected, cardiac enzymes negative, what is the next step?
Repeat cardiac enzymes at 6 hours
Considered negative after 2 sets of negative enzymes
Troponins vs CK-MB
- Troponins
- rise more immediately
- declines slower
- peaks at 18 hours
- CK-MB
- Declines more quickly
- Measure to test for repeat infarct
Drugs used for Pharm Stress Testing
- Dobutamine
- Adenosine
When to use different types of stress testing?
EKG, ECHO, Nuclear
- EKG
- Test of choice, no baseline abnormality
- ECHO
- EKG abnormalities. No CABG
- Nuclear:
- CABG, Baseline wall motion defects, BBB
Tx: Chronic CHF
- Always: beta-blocker and ACE-i
- Stage II: Add Furosemide
- Stage III: 1 and 2. Add Spironolactone or Hydralazine + Isosorbide Dinitrate
- Stage IV: Inotrope: Dobutamine or Milrenone. VAD bridge to transplant
- Stage I-III and EF < 35%: AICD
- Ischemic: Add Aspirin and Statin
Dx: Possible Chronic CHF
- BNP
- ECHO
- Left Heart Cath
Dx: Acute CHF Exacerbation
- CXR: volume overload?
- BNP
- ECG and troponins: r/o ischemia/arrhythmia as cause
- ECHO: not necessary but often done
Tx: CHF Exacerbation
“LMNOP”
- L = Lasix
- M = Morphine
- O = Oxygen
- P = Position
Note: initiating a beta-blocker during acute exacerbation is CONTRA (acutely decreases EF). If already on it, may continue
Differentiating CHF vs ARDS?
CHF = cardiogenic pulm edema; PCWP > 12
ARDS = non-cardiogenic pulm edema; PCWP < 12
HTN recommendations (JNC-8)
- >/= 60 + No Dz = 150/90 goal
- Everyone else = 140/90 goal
- CCB, Thiazide, or ACE-i as first line
- (>75) or AA = No Ace-i
- CKD = ACE-i/ARB (overrules #4)
- Don’t use beta blockers alone for HTN (add for CAD/MI)
Tx Hypertensive Urgency
PO Meds (hydralazine)
Tx: Hypertensive Emergency
IV Meds (Labatalol, CCB, Nitrates)
Rule: IV meds to decrease BP by 25% in first 2-6 hours. Then switch to PO with goal to reduce to normal within 24 hours.
Side effects of CCB
Peripheral edema
Side effects of ACE-i
- Increase K
- Increase Creat
- Angioedema
- Cough
Side effects of Thiazide diuretic
- Decreased K
- Gout
- Urinary Freq
- ***Stop if GFR decreased***
Side effects of Loop Diuretic
- Decrease K
- Urinary Frequency
Side effects of Beta Blocker
Decreased HR
Side effects of Arterial Dilators (ex Hydralazine)
Reflex tachycardia
Side effects of Aldosterone Ant (ex: spironolactone)
- Increased K
- Gynecomastia (switch to eplerenone)
HTN and Hypo-K
Hyperaldosteronism
- Dx:
- Aldo:Renin > 20
- CT pelvis
- Aldo:Renin > 20
HTN, renal bruit, hypo-K
Renovascular, 2ndary HTN
- Dx
- Creatinine Clearance
- BMP
- Aldo:Renin < 10
- Renal artery U/S
HTN, palpitations, perspiration, pallor, pain
Pheochromocytoma
- Dx:
- Urinary metanephrines
- CT
HTN, diabetes, central obesity, moon facies
Cushing’s
- Dx:
- Low dose dexamethasone suppression test
- ACTH lvl
- High dose dexamethasone
Name murmur & Tx
(Apex)
Mitral stenosis
(Opening snap, diastolic decresc. murmur)
Tx: Balloon Valvotomy
Name murmur & Tx
(R sternal border)
Aortic Stenosis
(Cresc/Decresc murmur in systole)
Tx: Valve replacement + CABG