Cardiology Flashcards
Tx CAD
- Always: ASA, statin, beta-blocker, ACE-i
- Nitrate: if continued chest pain
- CONT if R-sided infarct (leads II, III, avF)
- Clopidogrel: if stented
- x 1 mo for bare metal
- x 1 yr for drug-eluting (best)
- Heparin + Clopidogrel Load if
- NSTEMI
- High pretest probability CAD
- Other:
- Morphine - CONT in R-sided infarct (venodilator)
Drugs CONT in R-sided infarct
- Nitrate
- Morphine
Both are venodilators, decreasing preload. R-sided infarct is preload-dependent
Next step in R-sided infarct
IVF
(b/c it is preload-dependent and this will increase preload. Don’t be tricked by JVD. IVF is okay if no signs of pulmonary congestion)
If recent onset of CP, NSTEMI suspected, cardiac enzymes negative, what is the next step?
Repeat cardiac enzymes at 6 hours
Considered negative after 2 sets of negative enzymes
Troponins vs CK-MB
- Troponins
- rise more immediately
- declines slower
- peaks at 18 hours
- CK-MB
- Declines more quickly
- Measure to test for repeat infarct
Drugs used for Pharm Stress Testing
- Dobutamine
- Adenosine
When to use different types of stress testing?
EKG, ECHO, Nuclear
- EKG
- Test of choice, no baseline abnormality
- ECHO
- EKG abnormalities. No CABG
- Nuclear:
- CABG, Baseline wall motion defects, BBB
Tx: Chronic CHF
- Always: beta-blocker and ACE-i
- Stage II: Add Furosemide
- Stage III: 1 and 2. Add Spironolactone or Hydralazine + Isosorbide Dinitrate
- Stage IV: Inotrope: Dobutamine or Milrenone. VAD bridge to transplant
- Stage I-III and EF < 35%: AICD
- Ischemic: Add Aspirin and Statin
Dx: Possible Chronic CHF
- BNP
- ECHO
- Left Heart Cath
Dx: Acute CHF Exacerbation
- CXR: volume overload?
- BNP
- ECG and troponins: r/o ischemia/arrhythmia as cause
- ECHO: not necessary but often done
Tx: CHF Exacerbation
“LMNOP”
- L = Lasix
- M = Morphine
- O = Oxygen
- P = Position
Note: initiating a beta-blocker during acute exacerbation is CONTRA (acutely decreases EF). If already on it, may continue
Differentiating CHF vs ARDS?
CHF = cardiogenic pulm edema; PCWP > 12
ARDS = non-cardiogenic pulm edema; PCWP < 12
HTN recommendations (JNC-8)
- >/= 60 + No Dz = 150/90 goal
- Everyone else = 140/90 goal
- CCB, Thiazide, or ACE-i as first line
- (>75) or AA = No Ace-i
- CKD = ACE-i/ARB (overrules #4)
- Don’t use beta blockers alone for HTN (add for CAD/MI)
Tx Hypertensive Urgency
PO Meds (hydralazine)
Tx: Hypertensive Emergency
IV Meds (Labatalol, CCB, Nitrates)
Rule: IV meds to decrease BP by 25% in first 2-6 hours. Then switch to PO with goal to reduce to normal within 24 hours.
Side effects of CCB
Peripheral edema
Side effects of ACE-i
- Increase K
- Increase Creat
- Angioedema
- Cough
Side effects of Thiazide diuretic
- Decreased K
- Gout
- Urinary Freq
- ***Stop if GFR decreased***
Side effects of Loop Diuretic
- Decrease K
- Urinary Frequency
Side effects of Beta Blocker
Decreased HR
Side effects of Arterial Dilators (ex Hydralazine)
Reflex tachycardia
Side effects of Aldosterone Ant (ex: spironolactone)
- Increased K
- Gynecomastia (switch to eplerenone)
HTN and Hypo-K
Hyperaldosteronism
- Dx:
- Aldo:Renin > 20
- CT pelvis
- Aldo:Renin > 20
HTN, renal bruit, hypo-K
Renovascular, 2ndary HTN
- Dx
- Creatinine Clearance
- BMP
- Aldo:Renin < 10
- Renal artery U/S
HTN, palpitations, perspiration, pallor, pain
Pheochromocytoma
- Dx:
- Urinary metanephrines
- CT
HTN, diabetes, central obesity, moon facies
Cushing’s
- Dx:
- Low dose dexamethasone suppression test
- ACTH lvl
- High dose dexamethasone
Name murmur & Tx
(Apex)
Mitral stenosis
(Opening snap, diastolic decresc. murmur)
Tx: Balloon Valvotomy
Name murmur & Tx
(R sternal border)
Aortic Stenosis
(Cresc/Decresc murmur in systole)
Tx: Valve replacement + CABG
Name Murmur & Tx
(Apex)
Mitral Valve Prolapse
(mid-systolic click)
Tx: beta blockers, avoid dehydration
Name Murmur & Tx
(Apex)
Mitral Regurg
(holosystolic)
Tx: Valve Replacement
Name murmur & Tx
(R sternal border)
Aortic Regurg (Insufficiency)
Diastolic decresc murmur
Tx: Valve Replacement + CABG
Cause of mitral stenosis?
Rheumatic fever
(Past strep infxn)
Murmurs that increase with squatting/leg lift
- Mitral Stenosis
- Aortic Stenosis
- Mitral Regurg
- Aortic Regurg
(Squatting/Leg lift = Causes increased preload)
Murmurs that Increase with Valsalva
- Mitral Valve Prolapse
- Hypertrophic Obstructive Cardiomyopathy
(Valsalva increases Preload)
Dx in any murmur
ECHO
Dx Cardiomyopathy
ECHO
Possible Bx (Restrictive)
Tx: Syncope on exertion in young athlete w/ family hx of sudden cardiac death
Hypertrophic Obstructive Cardiomyopathy
Tx:
- Beta-blocker = CCB (diltiazem/virapamil)
- EtOH ablation
- Myectomy
- All 1st degree relatives should be screened
Tx Hypertrophic Cardiomyopathy
(NOT HOCM)
- Beta-blocker = CCB
- BP control
Note; Concentric hypertrophy on ECHO. HOCM has assymetric hypertrophy
Tx: Restrictive Cardiomyopathy
Beta-blocker = CCB
Gentle Diuresis (Diastolic HF, so be careful)
Dx: CHF + Peripheral Neuropathy
Restrictive Cardiomyopathy 2ndary to Amyloidosis
- Dx:
- Fat Pad/Gingival Bx
- if (-), Myocardial Bx
Note: Assoc. w/ MM
Dx: CHF + Lung Dz
Restrictive Cardiomyopathy 2ndary to Sarcoidosis
- Dx:
- Cardiac MRI
- Endomyocardial Bx
Dx: CHF + Cirrhosis
Restrictive Cardiomyopathy
- Dx:
- Ferritin
- Cardiac MRI
- Endomyocardial Bx
Dx: CHF + MM
Restrictive Cardiomyopathy 2ndary to Amyloidosis
- Dx:
- Fat Pad/Gingival Bx
- if (-), myocardial bx
Dx: CHF + Bronze DM
Restrictive Cardiomyopathy 2ndary to Sarcoidosis
- Dx:
- Cardiac MRI
- Myocardial biopsy
Pt w/ positional CP that is Pleuritic and a Multiphasic Friction Rub. Dx and Tx?
Pericarditis
- Dx:
- EKG (first test)
- PR segment depression (pathog)
- Diffuse ST segment elevation
- Best: MRI
- EKG (first test)
- Tx:
- Best: NSAIDS + Colchicine
- Colchicine only in CKD, Thrombocytopenia, PUD (anything that can’t have NSAID)
- NSAID only if diarrhea with colchicine
- Steroids if all else fails (High rate relapse). BAD in viral.
Pt w/ positional CP + SOB. Dx and Tx?
Pericardial Effusion
- Dx
- ECHO
- Tx:
- Treat pericarditis (NSAIDS +/- Colchicine) b/c this is most likely etiology
- Refractory: Pericardial window (allows to drain to thoracic cavity)
Pt w/ JVD, Muffled Heart Sounds, Clear Lungs. Dx and Tx?
Pericardial Tamponade
- Dx:
- DON’T TAKE TIME FOR THIS
- Tx:
- Emergency Pericardiocentesis
Pt w/ knocking on cardiac auscultation
Constrictive Pericarditis
(Pericardial Knock)
- Dx: ECHO
- Tx: Pericardiectomy
Pt. w/ Syncope of sudden onset (no prodrome)
Arrhythmia
- Dx:
- EKG
Pt w/ Syncope of sudden onset and Focal Neuro Deficit
Neurogenic: Vertebrobasilar Insufficiency
- Dx:
- CT angiogram
- Tx:
- Medical Management
- Stenting
Pt. w/ Sycope on Exertion
Mechanical Cardiac
- Etiology
- Aortic Stenosis
- HOCM
- LA Myxoma
- Saddle Embolus
- Dx:
- ECHO
- Tx:
- Tx underlying dz
Tx: Vasovagal Syncope
Beta-blockers
Tx: Orthostatic Syncope
Rehydrate/Transfuse
Steroids if that fails
Who needs a Statin?
- Vascular Dz = MI, CVA, PVD, CS
- LDL >/= 190
- LDL 70-189
- Age 40-75
- DM
- LDL 70-189
- Age 40-75
- Calculated Risk = 2 or more Risk Factors
- Smoking
- HTN
- Obesity
- Age >55 for women, >45 for men
- DM
- Dyslipidemia
- Calculated Risk = 2 or more Risk Factors
***Start High-Intensity Statin (Atorvastatin, Rosuvastatin)
Baseline Labs to Start Statins
- HbA1c = q3mo
- Lipids = annually
- CK = at beginning and if symptoms
- LFTs = at beginning and if symptoms
Dx: Pt on statins and begins having muscle pain
Statin-Myositis?
- Dx:
- CK
- U/A
Who should get a moderate-intensity statin?
- Liver Dz
- Kidney Dz
- Age > 75
- Statin-Intolerance
2nd Line Tx if can’t use Statin?
Fibrates
(Same side effect profile, same labs)
SVT
distinguished from Sinus Tachy by HR > 150 and no p-waves
Tx: Adenosine
V-tach
Tx: Amiodarone / Lidocaine
Afib
Tx: beta-blocker = CCB (verapamil/diltiazem)
Sinus Brady
Tx: Atropine
1st Degree AV Block
Tx: Atropine
2nd Degree AV Block Type 1
Tx: Atropine
2nd Degree AV Block Type 2
Tx: Shock! (pace) (Atropine no longer works)
3rd Degree AV Block
Tx: SHOCK (pace)
Idioventricular Rhythm
Tx: SHOCK (pace)

Torsades de pointes
Tx: Mg
Tx: Valvular Afib
Warfarin + LMWH bridge
Tx: Non-valvular Afib
Warfarin or NOAC, No LMWH bridge