Cardiology Flashcards
What is a “significant” family history for CAD?
MI in female relative less than 65
Male relative less than 55
How long does angina d/t ischemia typically last?
15-30 minutes
S3 gallop signifies?
Dilated left ventricle
S4 gallop signifies?
Left ventricular hypertropy
How quickly does CK-MB rise and stay elevated?
Rises in 3-6 hrs, the same as Troponin, but stays elevated only 1-2 days. That’s why CK-MB is the best test to detect reinfarction a few days after an initial infarct.
How quickly does Troponin rise and stay elevated?
Rises in 3-6 hrs, same as CK-MB, but stays elevated for 1-2 weeks.
What is “low” “intermediate” and “high” risk Framingham scores?
Low is 0-9% 10 year CAD risk
Intermediate is 10-20%
High is >20%
What are the expected annual rates of CAD death or MI for “low”, “intermediate”, and “high” risk Framingham scores?
Low - 2%
Which patient should receive pharmacologic stress test instead of exercise stress?
Those who cannot exercise to target heart rate of >85% of maximum
Which patient should receive cardiac radionuclide stress testing? (ECHO, Cardiac CT, MRI)
Patients whose EKGs are unreadable for ischemia:
- LBBB
- Digoxin use
- Pacemaker
- Left ventricular hypertrophy
- Baseline abnormality of the ST segments on EKG
What instance does an ACEi or ARB lower mortality in acute coronary syndromes?
If their is low EF or systolic dysfunction
What are examples of GPII/IIIa inhibitors?
Eptifibatide, Tirofiban, or Abciximab
When is GPII/IIIa inhibitors shown to be beneficial in ACS?
In the setting of NSTEMI, especially when combined with angioplasty and stenting.
When should thrombolytics be used in STEMI?
When PCI cannot be performed within 90 minutes of presentation AND
- chest pain has been for less than 12 hrs
- ST segment elevation in 2 or more leads or new onset LBBB
Indications for CABG?
3 coronary vessels with >70%
Left main disease with >70%
Patient with CHF and pulmonary edema, is Wedge pressure increased or decreased?
Increased, because there is increased L atrial pressure.
Drugs used to treat diastolic dysfunction CHF?
Beta blockers and diuretics
- Spironolactone and Digoxin not shown to be beneficial
- ACE-i not definite if it helps.
CHF patient with maximal medical therapy and still symptomatic, QRS duration >120 msec, what do you do next?
Place biventricular pacemaker, aka “cardiac resynchronization therapy”
Valvular disease associated with Turner syndrome?
Bicuspid aortic valve
Valsalva and standing up do what to venous return to the heart?
Decrease venous return to the heart
Squatting and lifting legs in the air do what?
Increase venous return to the heart.
Most murmurs increase with squatting and leg raise, which are the only two murmurs to decrease with that?
Mitral Valve Prolapse and HOCM
Murmur in second right intercostal space that radiates to carotids, crescendo-decrescendo?
Aortic stenosis