Cardio Vascular System: Blood Chapter 19 Flashcards
3 Components of the circulatory system
heart, blood, and blood vessels
The cardiovascular system is the first system developed by week ___ of gestation
3
The heart serves as a pump and has to have a form of _________.
transportation
5 Purposes of blood
- Transportation
- Regulation of pH
- Maintenance of Body temp
- Protection Against Foreign Substances
- Clot Formation
Blood transports which gases and what else?
oxygen, carbon dioxide, and waste, nutrients, and vitamins, and regulatory molecules and hormones/enzymes
pH is regulated by
hydrogen
______ buffer system
bicarbonate
acid indicates _____ hydrogen
high
base indicates ______ hydrogen
low
bicarbonate buffers concentrations of _________
hydrogen
the bicarbonate buffers concentrations of hydrogen by ________ concentrations in acids and __________ concentrations in bases.
absorbing, providing
warm blood shunts to the surface to release heat when hot, thus ______.
sweating
blood will stay inside of deeper tissue to maintain heat loss when ______
cold
Blood has access to parts of your body that could be invaded by _____
pathogens
2 Cells in the blood that fight against pathogens
WBC and antibodies
Clot formation _____ blood loss
seals
______ monitor blood loss
platelets
a collection of _____ form a clot at damage
cells
blood clots prevent blood ___
loss
blood is _______ tissue
connective
Blood has an extensive ________ ______ thus meaning fewer cells
extracellular matrix
extracellular matrix is ______
fluid
55% of blood is
plasma
45% of blood is
hematocrit
hematocrit Is the percentage of _______ components
cellular
a ________ is a solution that contains a substance that doesn’t settle out (plasma)
colloid
____% of blood is water
91
3 Proteins found in blood consist of
Albumins, globulins, and fibrinogen
Antibodies are types of
globulins
_______ regulate osmotic pressure and osmosis and transportation
albumins
________ transport and work with immunity
globulins
_________ are blood clotting fibers
fibrinogen
plasma without the clotting factor is called
serum
______ are made of ions, nutrients, waste, gases, and regulatory substances
hormones
3 Cell fragments in blood are
Erethrocytes, leukocytes, and thrombocytes
__________/_________ is the formation of RED blood cells
Hematopoiesis/Hemopoiesis
ALL blood cells are derived from __________ (a stem cell)
Hemocytoblasts
All cells come from _______ cells (hemocytoblasts)
myeloid cells
Lymphocytes come from ______ cells (hemocytoblasts)
lymphoid cells
_________ have a biconcave disc
erythrocytes
biconcave disc allows for flexibility and to pass through ______ _______
blood vessels
Erythrocytes are _______ and lose their nucleus during maturity
anucleate
Because erythrocytes are anucleate they are incapable of ______ and cannot repair damage
mitosis
Erythrocyte life span is
120 days
Blood is full of what oxygen carrying protein
hemoglobin
Oxygen is transported by attaching to ______
hemoglobin
Carbon dioxide is primarily transported by ______.
bicarbonate
Globin is the ______ and heme is the _______
protein, iron
There are _ global and _ heme per HEMOGLOBIN
2, 2
_______ hemoglobin is the first globin to activate in your genes
embryonic
_______ hemoglobin replaces at the 3rd month of development
fetal
_______ hemoglobin replaces 60-90% at birth and has a weaker affinity for ocygen
adult
______ means it is bound to oxygen
oxyhemoglobin
______ means it is not bound to oxygen
deoxyhemoglobin
__________ means it is transporting carbon dioxide
Carbaminohemoglobin
When transporting carbon dioxide, the carbon dioxide attaches to the protein ______ instead of the heme
globin
________ means transporting carbon monoxide
carboxyhemoglobin
When transporting carboxyhemoglobin, there is no room for ______ which leads to death
oxygen
_______ gives blood its red pigment
iron
__________ is the process of producing new red blood cells
Erythropoiesis
After coming from a myeloid cell, and before becoming an erythrocyte, a call must become a ___________ first.
reticulocyte
___________: the stage before becoming an erythrocyte
reticulocyte
___________ happens when there is too any reticulocytes in the blood because the blood is losing red blood cells and is trying to make more.
Reticulocytosis
_____ ________ levels sense and stimulate RBC production
Low oxygen
the hormone _______ stimulates erythropoiesis
erythropoietin
________ is an abnormal break down of blood
hemolysis
________ anemia is anemia from hemolysis
hemolytic
_______cell anemia is a mutation in hemoglobin, sickle cell in shape and has less room for oxygen transport
sickle
_________ _____ cells possess nucleus, no hemoglobin, and protect against micro organisms and remove dead cells and debris
white blood
__________ movement is how WBC move, and it is directed movement using pseudopods
ambeoid
_________ is the process of cells morphing to fit into the endothelial of cell capilaries
Diapedesis
_______ is the attraction toward foreign material and dead cells
chemotaxis
Granulocytes mean granules lack in cytoplasm (T/F)
False
_______ are most prevalent WBC and fight inflammatory responses and are FIRST responders at sight of injury. They are phagocytic and secrete lysosomes
Neutrophils
________ fight parasites, are less common, and most prevalent in calming an allergic reaction
eosinophils
_______ are inflammatory responses to allergies
basophils
_______ include T and B Calls and fight bacteria and viral infections in the body
Lymphocytes
_______ are macrophages that eat bacteria
monocytes
________ is the cessation of blood loss
Hemostasis
The three steps in Hemostasis
- Vascular Spasm
- Platelet Plug formation
- Coagulation
Vascular spam includes _______ of damaged blood vessels
vasoconstriction
Platelet Plug formation is a temporary plug that involves 3 steps…
- Platelet Adhesion
- Platelet Release Reaction (chemically activated/positive feedback)
- Platelet aggregation (where fibrinogen turns to fibrin)
Clot formation/Coagulation includes two pathways that merge into one, what are they?
Extrinsic and Intrinsic pathways merge to be one common pathway
Extrinsic pathways are on the outside of the blood stream and begin at _________ tissue
damaged
Intrinsic Pathways are chemical pathways that begin _______ of the blood stream
Inside
_________ is the enzyme that activates the change of prothrombin to thrombin
Prothombinase
_________ is the breaking of fibrin, the dissolving of a blood clot
Fibrinolysis
actin and myosin act in _________
contraction
______ is a blood clot in the bloodvessels
thrombus
A free floating blood clot is an ________
embolus
Clot formation can be controlled by _________ that prevents clotting factors
anticoagulants
______ is the name tag for the blood
antigen
positive Rh if Rh is absent (T/F)
False
the _______ are opposite of your receiving blood type
antibodies
________ is the binding of red blood cells to antibodies
agglutination
______ is binding of fiber and platelets
Clotting
Antibodies attack the ______ that the blood type does not have
antigen
________ disease of a new born is when the RBC’s rupture when mother and baby have a different Rh and then the mother’s RBC antibodies produce antigens against the baby’s Rh.
Hemolytic
(rhoGam injection stops this)
Where there is clumping, there are ________
antigens
What is hematocrit measurement
RBCs/total blood volume (%)