cardio/pulm Flashcards
What are 4 main triggers for asthma?
Weather change
Aspirin
Beta blockers
Viral URI
How many children will outgrow mild asthma ?
60%
What is the trend in asthma mortality?
Mortality of asthma is increasing!
Is asthma more common in boys or girls?
More common in boys until puberty - but later it is equal in boys and girls
What are the 3 clinical descriptions associated with mild intermittent asthma?
Symptoms less then 2x weekly
Night symptoms less then 2x monthly
No pulmonary function abnormalities
What are the 3 clinical descriptions associated with mild persistent asthma ?
Normal PFTs
Symptoms more than 2x per week
Night symptoms more than 2x per month
What is the treatment for mild persistent asthma?
Low dose inhaled steroids
2nd line - leukotriene inhibitor
What is the treatment for moderate persistent asthma?
Low to medium dose steroid + laba
When do you classify a child as having moderate persistent asthma?
When a child requires bronchodilators more than twice per week
What is the definition of mild exacerbation of asthma ?
Decreased pulmonary function but still >50% of predicted
When is levalbuterol indicated instead of albuterol?
Only in patients with tachycardia, tremors or irritability
When is chest PT and mucolytics indicated for asthma?
Never
What are 5 side effects of beta adrenergic agonists?
Tremors Tachycardia Hypokalemia Hyperglycemia Hypomagnesemia
What does high or low CO2 indicate in the setting of acute asthma?
High pCO2 indicates CO2 retention and fatigue with respiratory failure
Low pCO2 reflects tachypnea
What are 5 signs of hypercapnia?
Agitation Flushing Altered mental status Headache Tachycardia
What is the most common cause of chronic nighttime cough?
Reactive airway disease
What are 4 main causes of infant wheezing, other than asthma?
Aspiration
Bronchopulmonary dysplasia
Foreign body
Vascular rings
What is the definition of exercise induced asthma?
Coughing and wheezing 5 minutes after exercising with improvement within 15 minutes of rest
What diagnosis should you consider in a patient with a “respiratory infection that is not clearing”?
Foreign body
What are the 4 main causes of poor exercise tolerance ?
Cardiac disease
Anemia
Muscle weakness
Psychological factors
What medication may be indicated for exercise induced asthma?
Leukotriene inhibitor (montelukast)
What are the 4 risk factors for persistent asthma ?
Onset before age 3
IgE elevated
Maternal hx asthma
Eosinophilia
What diagnosis must be considered in a patient with unlabored breathing but sudden onset of intermittent productive cough and wheezing?
Foreign body aspiration
What diagnosis corresponds with blunted inspiratory loop on spirometry?
Vocal cord paralysis
What is the safest and most effective way to confirm foreign body aspiration?
Airway fluoroscopy
What is the treatment for a swallowing dysfunction ?
Thickened formula and upright feeding position
What are 3 signs of respiratory failure ?
Tachypnea
Retractions
Pulsus paradoxus
What is pulsus paradoxus?
When the difference in blood pressure during inspiration and expiration is >10mmHg
What is the first thing to do when deciding whether to intubate a patient ?
Assess respiratory effort
What is the best way to assess for the severity of respiratory distress ?
Sweating / fast heart rate
What is the proper way to administer oxygen in a patient with chronic lung disease and why?
At the lowest concentration needed to maintain sats above 90 …rapid correction of hypoxia can lead to respiratory arrest because respiratory drive is driven by hypoxia
What are 3 initial screening tests for a chronic cough?
Sweat choride test
Tb skin test
Cxr
What value indicates an abnormal sweat chloride test?
> 60
How is cystic fibrosis inherited?
Autosomal recessive (carriers show no signs of disease)
What is the most effective test for confirming cystic fibrosis?
Sweat chloride
What disease should you suspect in an infant with hypochloremic alkalosis ?
Cystic fibrosis
If a sibling of someone with CF marries someone in the general population, what are the odds of them having a child with CF?
1 in 150
If two carriers of CF are married, what is the risk they will have a child with Cf?
1 in 4
What is the carrier rate of CF in the general population ?
1 in 25
What are the odds of a healthy sibling of someone with CF being a carrier?
2/3
What vitamin may be deficient in patients with CF? What should be done about this deficiency ?
Vitamin E (supplements should be started prior to age 5)
What lab study if abnormal in patients with vitamin K malabsorption?
Prolonged PT
What are 3 common GI manifestations of CF in the neonatal period?
Meconium ileus
Meconium peritonitis
Unconjugated hyperbilirubinemia
What are the X-ray findings of meconium peritonitis?
Pseudocyst (calcified meconium)
What is the abdominal film appearance with meconium ileus?
Ground glass appearance due to decreased bowel gas
What is the antibiotic treatment of an acute exacerbation of CF?
Aminoglycoside and piperacillin (for pseudomonas coverage )
What diagnosis should you consider in a patient with lower body edema, hepatomegaly, gallop heart rhythm and clubbing of fingers?
Cor pulmonale
What causing flushing and agitation as well as headaches due to cerebral vasodilation?
Hypercarbia
How is apnea of prematurity treated?
Caffeine
What are 4 main causes of central apnea which must be ruled out before the diagnosis “apnea of prematurity” is given?
Sepsis
Medication
Anemia
Electrolyte abnormalities
What is the likely cause of a patient in acute respiratory distress who is post-op tonsillectomy due to history of obstructive apnea?
Pulmonary edema
What is the definition of apnea?
Cessation on breathing >20 seconds or <20 seconds if associated w bradycardia or cyanosis
What is the diagnosis in a patient with pleural fluid that has >110 triglycerides, high lymphocytes and protein >3?
Chylothorax
When is pleural effusion likely to be an “exudate”?
With pneumonia, Cancer, inflammation or trauma
What will the fluid LDH and protein levels be in an exudative pleural effusion?
LDH 3x the serum LDH
Protein >3 grams
What are 3 causes of transudative pleural effusion?
Cirrhosis
Nephrotic syndrome
CHF
What is the triglyceride level in transudative pleural fluid?
<50
What is the diagnosis and treatment for a patient with tachypnea, tachycardia, low BP and tracheal deviation ?
Tension PTX - needle or chest tube ASAP
What are 3 causes of respiratory deterioration in an intubated patient?
Tension PTX
Incorrect tube positioning
Equipment failure
What are 6 main risk factors for SIDS ?
Sleeping on tummy Co sleeping Low income Smoking Cold weather Young parents
What are 6 possible causes of ALTE in an infant?
Neurological abnormality Abuse/trauma Lung infection / apnea Sepsis Hypoglycemia Gerd / aspiration
When can an infant with ALTE be discharged home from the ER?
First episode that is brief and presents with an explanation (uri or reflux)
What is the initial step when presented with an infant with noisy breathing?
Birth history and observe breathing in different positions
What is the only way to correlate pulse oximetry and pulmonary lung function?
ABG (CBG is unreliable)