Cardio Flashcards
Angina Pectoris Path
Exertional chest pain d/t increased demand and decreased supply
Typically caused by fixed plaque
Pain lasts LESS THAN 30 minutes and is relieved by rest and/or Nitro
Classes of Angina
I: only with unusally strenuous activity, no limitations
II: with more prolonged/rigorous activity, slight limit
III: with usual daily activity, marked limts
IV: at rest, unable to do activity
Dx of Ischemic Heart Disease
EKG: ST depression
Stress test: most useful noninvasive tool
Myocardial Perfusion imaging
Coronary angiography: GOLD STANDARD
Surgical Tx of ischemic heart disease
PTCA: not involving the left main coronary artery, vent function is near normal
CABG: for left main coronary or critical stenosis
Nitro and ischemic heart disease
Increases O2 and increases collateral blood flow, reducing coronary vasospasm and increasing dilation.
If no relief with first dose give a 2nd and 3rd evert 5 minutes. If still not relief – ACS!!!
Contraindications to Nitro
SBP <90
RV infarction
PDE-5i’s
BBs
increase diastolic timing, first line drug of choice for ischemic heart disease management
CCBs
used by patients that cannot use BBs, Prinzmetal angina
Prinzmetal angina
almost ALWAYS occurs at rest, usually between midnight and early morning
ASA and ischemic heart
prevents progression of stable angina to ACS
CAUTION in pts with PUD or increased bleeding risk
Sinus Arrhythmia
Same as NS except irregular
HR increases during inspiration and decreases with expiration
Since sinus syndrome
“Brady-Tachy”
Combo of sinus arrest with alternating paroxysms of atrial tach and brady. Commonly caused by sinoatrial node disease
NEED PACER
AV block
Interuption of normla impulse from SA to AV
A Flutter
Saw tooth waves @ 250-350 BPM with no P waves.
Rate: regular
Stable: vagal, BB, CCB
Unstable: cardiovert
Cure: ablation
Afib
Rhythm: Irregular
Narrow QRS
No p wave
80-140bpm
Can lead to ischemic stroke
Ashmens Phenomenon
occasional aberrantly conducted beats and short R-R cycles
AFIB MANAGEMENT of stable patients
rate control
BB: metoprolol but be careful in pts with reactive airway disease
CCB Diltiazem
Digoxin: Preferred in pts with hypotension or CHF
Rhythm Control: cardiovert, flecinide, sotalol, amiodarone, ablation
Afib management o Unstable patients
Cardiovert
Anticoags for Afib
Warfarin w/ goal INR 2-3
Dual Antiplatelet: ASA + clopidogrel
Long QT syndrome
d/t congenital or macrolides/TCAs and electrolyte abnormalities. Can lead to sudden cardiac death
Tx: d/c offending med and correct abnormalities
Congenital: AICD
PSVT
HR>100
Regular, narrow QRS, P waves hard to see
Paroxysmal: sudden onset and termination
PSVT types
AV nodal reentry: 2 pathways both within AV node –> MC
AV reciprocating Tach: 1 pathway in AV and second outside AV
PSVT tx
Stable: vagal, adenosine 1st line, BB/CCB
Unstable: cardiovert
Cure: ablation
Wandering atrial pacemaker/ Multifocal Atrial Tach
WAP: <100 BPM >/= 3 P waves
MAT: >100 BPM >/= 3 P waves –> SEVERE COPD
Wolff Parkinson White
Bundle of Kent excites ventricles
DELTA waves
Wide QRS
Short PR
Tx: vagal, antiiarhythmics, procainamide
AVOID ABCD: adenosine, BBs, CCBs, Digoxin
Lown Ganong Levine Syndrome
Short PR with normal QRS
Bundle of James connects with His
PVC
Premature beat from ventricle
WIDE bizarre QRS earlier than expected with a pause
T wave is opposite direction
Ventricular Tach
> /= 3 PVCs at a rate of >100bpm
No pulse: defib/CPR
Torsades De Pointes
MC d/t Hypomagnesemia, hypokalemia, V Tach that twists around baseline
Tx: IV mag
V Fib Tx
Unsynchronized cardiovert and CPR
PEA
NSR without a pulse
CPR/Epi
Dilated Cardiomyopathy etiology (95% of cases)
Post viral, MC is enterovirus
Also: chagas, ETOH, prego, cocaine
TAKE A GOOD Hx
Dilated Cardiomyopathy Sx
Systolic heart failure sx
S3
Laterally displaced PMI
Mitral/Tricuspid Regurg
Dilated Cardiomyopathy Dx/ Tx
Echo -> LV dilation, decreased EF
Tx: ACEi, Diuretics, BBs
Restrictive Cardiomyopathy etiology
Impaired disatolic function with preserved contractility
Amyloidosis MC cause
Also: sarcoidosis and infiltrative disease
Restrictive cardiomyopathy Sx/ PE
Right sided failure sx Kussmauls sign (JVP increases with inspiration)
Restrictive Cardiomyopathy dx/ tx
CXR: atrial enlargement, pulm congestion
Tx: tx sx and underlying issue
HOCM etiology
Genetic disorder of LV and/or RV hypertrophy
Subaortic outflow obstruction
HOCM Sx
Dyspnea MC CC, angina, syncope, arrythmias, sudden cardiac death
HOCM PE
HARSH systolic Cresendo-Decresendo murmur heard at lower left sternal border, similar to AS except HOCM decreases with squatting
HOCM Dx and TX
Echo: >15mm wall thickness
Tx: BB is 1st line, the myomectomy, and alcohol septal ablation
CHF L vs R
L: MC causes CAD and HTN
R: MC causes is left sided failure
CHF systolic vs diastolic
Systolic: decreased EF S3 MC form Etiology: post MI, dilated cardiomyopathy, myocarditis
Diastolic: normal EF
S4
Stiff ventricle
Etiology: HTN, LVH, Elderly
High Output CHF
metabolic demands of hte body exceed normal cardiac fxn
Thyrotoxicosis, wet beriberi, severe anemia, AV shunting
Low output CHF
Inherent problem of myocardial contraction, ischemia, chronic HTN
NY heart CHF Classificaiton
I: no sx/ limits
II: mild sx, slight limits
III: sx cause marked limits with activity, comfy at rest
IV: sx at rest, severe limits
Sx of L CHF
Increased pulmonary pressure from fluid backup
Dyspnea, Pulm edema/congestion (rales, rhonchi)
Productive cough, Transudative pleural effusions
HTN, S3/S4, cheyne stokes breathing, dusky pale skin, diaphoresis, sinus tachy, cool extremities
Sx of R CHF
Peripheral edema, JVD, GI/Hepatic congestion
N/V, RUQ t, Anorexia
CHF Dx
Echo for EF
CXR: kerley B lines, butterfly pattern, cardiomegaly, Pulm Edema, Pleural Effusions
CEPHALIZATION: increased vascular flow to apices
Increased BNP
CAD
Inadequate perfusion d/t imbalance between decreased coronary blood supply and increased demand
MC etiology: artherosclerosis, AS,AR, Pulm HTN
Rsk: DM, Sm, HTN, HLD, Male, >45, Fam hx
CAD PE
Sx only with >70% reduction in lumen
ABI<0.9
Delayed cap refull, cool limbs, pale on elevation, lateral malleolar ulcers
CAD tx
Cilostazol, ASA
CVD
Atherosclerosis MC
DM (worst rsk factor)
Sm, HLD, HTN , Males, Age, Hx
ACS
UA, NSTEMI, STEMI
Retrosternal pressure not relieved by rest or nitro
a/w diaphoresis and n/v
UA/ NSTEMI tx
ASA, GPIIb/IIa i’s, BBs, Nitrates, CCBs
STEMI Tx
PCI within 3 hours of onset. Alteplase if no PCI
Exceptions to STEMI Tx
Cocaine: NO BBs
R vent infarct: give IVF, no nitrates or morphine
Viagra: no nitrates
Lateral leads
I, aVL, V5-V6
Inferior Leads
II, III, aVF
Anterior/Septal leads
V1-V4
Endocarditis
Mitral valve MC
IVDA –> tricuspid MC
Types of endocarditis
Acute bacterial (S. Aureus)
Subacute Bacterial (S. Viridans)
IVDA: MRSA
Prosthetic: S. Epidermis
HACEK
Haemophlius, Actinobacillus, Cardiobacterium, Eikenella, Klingella
Gram Neg organisms a/w large vegetations and hard to culture
Endocarditis
FROM JANE
Fever Roth Spots Osler Nodes Murmur Janeway Lesions Anemia Nailbed Hem Emboli
Duke Criteria
Blood Cx: 3 sets at least 1 hour apart
EKG: arrythmias
Echo: TTE first, consider TEE
Labs: Leukocytosis, anemia, increased EST/rheumatoid factor
Tx of Endocarditis
Surgery indication
Refractory CHF, persistent infection, invasive, prosthetic valve, fungal
Tx of endocarditis acute/subacute
Native valve: Naficillin and Gentamicin 4-6 weeks
Subacute: PCN or Ampicillin and Gentamicin OR Vanc in IVDA
Tx of Endocarditis Prosthetic Valve
Vanc and Genta micin and Rifampin
PPX abx for endocarditis
Prosthetic valves, heart repairs with prosthetic material, prior hx of endocarditis, congenital heart disease
Procedures: dental, respiratory, infected skin
PPX regimen
Amoxicillin 2g 30-60 minutes prior to procedure
Hyperlipidemia Etiology
Hypercholesterolemia: hypothyroidism, pregnancy, kid failure
Hypertriglyceridemia: DM, ETOH, Obesity, Estrogen, Steroids
HLD Sx
Xanthomas, Xanthelasma, usually asx
Statin therapy guidelines
DM 40-75 y/o
CVD 40-75 y/o w/ >7.5% risk
>21 y/o w/ LDL >190
ANY ASVCD
Lipid medications
Lower LDL: statins
Lower Triglycerides: Fibrates
Increase HDL: Niacin
Type II DM: Fibrates/Statins
HTN
> 2 readings on >2 visits of >140 SBP and/or >90 DBP
Primary vs Secondary HTN
Primary: d/t idiopathic cause, onset 25-55, Fam hx
Secondary: d/t an outside cause
HTN sx
Papilledema, renal artery bruits, decreased femoral pulses, presence of S4
Goal BP
<140/90 for general population
<150/90 if > 60yo
Chlorthialidone
Prevents Kidney NA/H2O reabsorption
SE: hyponatremia, hypokalemia, hypercalcemia, hyperglycemia
Furosemide Loop Diuretic
Ihibits H2O transport
SE: Water depletion, hypokalemia/calcemia, hyperglycemia, acidosis, ototoxicity
Spirnolactone, amiloride
K sparing
Inhibits aldosterone mediated H2O and NA absorption
SE: hyperkalemia, gynecomastia
ARB
Contraindicated in Pregnancy
ACEi
Decreases preload/afterload
Good for DM, nephropathy, CHF, post MI
SE: azotemia, hyperkalemia, cough
CCB: Nifedipine, Amlodipine, Verapamil, Diltiazem
DHP> non DHP
SE: HA, flushing
Contraindicated in CHF 2/3 heart block
BBB Atenolol, metoprolol, esmolol, propanolol
SE: Fatigue, depression, impotence
Contraindicated in Heart block, CHF, Asthma, COPD, Raynauds, Hypotension
Prazosin/Terazosin
Good for HTN w/ benign prostatic hypertrophy
SE: Syncope, HA, Dizziness
Myocarditis
Inflamm of heart muscle MC d/t viral infection or post viral immune mediated cardiac damage
Myocarditis Sx
Viral prodrome: fever, malaise, myalgias, heart failure
Dyspnea at rest, exercise intolerance, syncope, tachy, AMS
Myocarditis Dx
CXR: cardiomegaly
Cardiac Enzymes: elevated CK-MB and troponin, and ESR
GOLD STANDARD: endomyocardial biopsy
Myocarditis Tx
Supportive mainstay of T, standard systolic heart failure
tx: diuretics, ACEi, IVIG, no BBs in peds
Acute pericarditis
Fibrinous inflammation of the pericardium
Enterovirus
Pericarditis Sx
Chest pain pleuritic persistent and postural
Fever
Pericardial friction rub at end of expieration whilte upright
Pericarditis Dx
EKG: ST elevations in precordial leads with PR depressions
Echo: assess for complications of pericarditis like effusion or tamponade
Pericarditis tx
NSAIDS/ASA for 7-14 days
Colchicine is 2nd line
PVD
Superficial
Deep
Perforating
Superficial Thrombophlebitis
Thrombus in superficial vein, d/t IV cath, trauma, preg, varicose veins
Superficial thrombophlebitis Dx/ Tx
Dx: venous duplex US
Tx: Supportive, elevation, warm compress, NSAIDS, stockings
Trousseau’s Malignancy
Migratory Thrombophelbitis associated with malignancy (Pancreatic CA)
DVT
U/L swelling of lower extremity >3cm is most specific sign
Dx: Venous Duplex is 1st line, VENOGRAPHY gold standard
Tx: Antigoag –> Heparin, IVC filter
Rheumatic fever
Autoimmine inflammatory multi systemic illness found in 5-15 y/o
MC: mitral complications
Rheumatic Fever PE
JONES criteria
- Joint pain
- Oh my heart
- Nodules
- Erythema Marginatm
- Sydenhams Chorea
Also: fever, elevated ESR/CRP, Positive throat culture of Group A strep
Rheumatic Fever Tx
ASA 2-6 weeks with taper, steroids
Pen G abx of choice
Aortic Stenosis Etiology
1: Degenerative heart disease
2: Congenital heart disease
3: Rheumatic heart disease
Aortic stenosis sx
Angina
Syncope
Congestive Herat Failure
SYSTOLIC CRES-DECRESEND MURMUR
RAD TO CAROTID
Narrow pulse pressure
Aortic stenosis tx
AoV replacement, balloon pump
Aortic Regurg Etiology
1: Rheumatic heart disease
2: Endocarditis
3: Aortic root dilation
Aortic Regurg sx
CHF, Bounding pulses, Wide pulse pressure
DIASTOLIC DECRESENDO BLOWING MURMUR
Aortic regurg tx
ACEi/ARB/Nifedipine, surg is definitive
Mitral Stenosis etiology
Rheumatic Heart Disease MC
Mitral Stenosis sx
Dyspnea, hemoptysis, cough, pulm HTN, Afib, R sided HF, Flushed cheeks
PROMINENT S1 OPENING SNAP, MID DIASTOLIC
Mitral stenosis tx
Surgery
can use diuretics for congestion or BB for afib
Mitral regurg etiology
Prolapse MC
2: Ischemia/infarct
3: Ruptured chordae tendinae
Mitral regurg sx
Acute pulm edema, hypotension, dyspnea, chronic afib, CHF
BLOWING HOLOSYSTOLIC
Mitral regurg tx
Surgery (repair>replacement)
OR
ACEi, hydralazine, nitrates
Mitral valve prolapse
Palpitations, syncope, fatigue, dyspnea, mostly ASX
MID-LATE SYSTOLIC EJECTION CLICK
Tx: none
Pulm Stenosis etiology
congenital
Pulm Stenosis sx
harsh misystolic ejection crescendo decrescendo murmur radiates to neck
Pulm Regurg etiology
pulm htn, TOF, endocarditis, rheumatic heart disease
Pulm Regurg Sx
brief decrescendo early diastolic murmur with inspiration
TX: none
Tricuspid stenosis sx
mid diastolic murmur
Tx: diuretics/ Na restriction
Tricuspid regurg sx
holosystolic blowing high pitched murmur
CARVALLOs SIGN: increased with inspiration
Tx: diuretics, HF therapy